An oxocarbenium-ion intermediate of a ribozyme reaction indicated by kinetic isotope effects

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 26, 2003, Pages 15393-15397

  Unrau, Peter J ^a   Bartel, David P ^b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBENOID; CARBON 13; HYDROLASE; ION; ISOTOPE; OXOCARBENIUM ION; PYRIMIDINE NUCLEOTIDE; PYROPHOSPHATE; RIBOZYME; UNCLASSIFIED DRUG; URACIL DNA GLYCOSYLTRANSFERASE;

ARTICLE; CATALYSIS; CHEMICAL BINDING; CHEMICAL BOND; CHEMICAL REACTION KINETICS; ENZYME ACTIVE SITE; HYBRIDIZATION; HYDROLYSIS; MOLECULAR STABILITY; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL;

BASE SEQUENCE; BINDING SITES; CATALYSIS; GLYCOSIDES; KINETICS; MOLECULAR SEQUENCE DATA; PYRIMIDINE NUCLEOTIDES; RNA, CATALYTIC;

EID: 0346103678     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2433147100     Document Type: Article

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