High Resolution X-ray Structure of dTDP-Glucose 4,6-Dehydratase from Streptomyces venezuelae

Journal of Biological Chemistry

Volumn 279, Issue 3, 2004, Pages 2211-2220

  Allard, Simon T M ^a   Cleland, W W ^a   Holden, Hazel M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BIOSYNTHESIS; CRYSTALLIZATION; CRYSTALLOGRAPHY; GENES; SUBSTRATES; SUGARS;

HIGH RESOLUTION X-RAY STRUCTURES; PROTON ABSTRACTION;

BIOCHEMISTRY;

3 (DIMETHYLAMINO) 3,4,6 TRIDEOXYHEXOSE; ASPARTIC ACID; BACTERIAL ENZYME; DESOSAMINE; GLUTAMIC ACID; HEXOSE; HYDROLYASE; HYDROXYL GROUP; MACROLIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUGAR; THREONINE; THYMIDINE DIPHOSPHATE; THYMIDINE DIPHOSPHATE 4,6 DEHYDRATASE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; CRYSTALLIZATION; DESIV GENE; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS; STREPTOMYCES VENEZUELAE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLIZATION; GLUCOSE; HYDRO-LYASES; HYDROGEN BONDING; STREPTOMYCES; THYMINE NUCLEOTIDES;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOMYCES; STREPTOMYCES VENEZUELAE;

EID: 0345826027     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310134200     Document Type: Article

References (39)

1. Xue, Y., Zhao, L., Liu, H. W., and Sherman, D. H. (1998) Proc. Natl. Acad. Sci. U. S. A 95, 12111-12116
2. Weymouth-Wilson, A. C. (1997) Nat. Prod. Rep. 14, 99-110
3. Tang, L., and McDaniel, R. (2001) Chem. Biol. 8, 547-555
4. Schlünzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., and Franceschi, F. (2001) Nature 415, 814-821
5. Hansen, J. L., Ippolito, J. A., Ban, N., Nissen, P., Moore, P. B., and Steitz, T. A. (2002) Mol. Cell. 10, 117-128
6. Khosla, C., and Zawada, R. J. (1996) Trends Biotechnol. 14, 335-341
7. Mendez, C., and Salas, J. A. (2001) Trends Biotechnol. 19, 449-456
8. Chen, S., Roberts, J. B., Xue, Y., Sherman, D. H., and Reynolds, K. A. (2001) Gene (Amst.) 263, 255-264
9. Kallberg, Y., Oppermann, U., Jörnvall, H., and Persson, B. (2002) Eur. J. Biochem. 269, 4409-4417
10. Jörnvall, H., Persson, B., Krook M., Atrian, S., González-Duarte, R., Jeffery, J., and Ghosh, D. (1995) Biochemistry 34, 6003-6013
11. Duax, W. L., Griffin, J. F., and Ghosh, D. (1996) Curr. Opin. Struct. Biol. 6, 813-823
12. Duax, W. L., Ghosh, D., and Pletnev, V. (2000) Vitam. Horm. 58, 121-148
13. Allard, S. T. M., Giraud, M. F., Whitfield, C., Graninger, M., Messner, P., and Naismith, J. H. (2001) J. Mol. Biol. 307, 283-295
14. Allard, S. T. M., Beis, K., Giraud, M. F., Hegeman, A. D., Gross, J. W., Wilmouth, R. C., Whitfield, C., Graininger, M., Messner, P., Allen, A. G., Maskell, D. J., and Naismith, J. H. (2002) Structure 10, 81-92
15. Beis, K., Allard, S. T. M., Hegeman, A. D., Murshudov, G., Philp, D., and Naismith, J. H. (2003) J. Am. Chem. Soc. 125, 11872-11878
16. Sambrook, J., and Russell, D. W. (2001) Molecular Cloning: a Laboratory Manual, 3rd Ed., Cold Spring Harbor Laboratory Press, New York
17. Okazaki, R., Okazaki, T., Strominger, J. L., and Michelson, A. M. (1962) J. Biol. Chem., 237, 3014-3026
18. Gross, J. W., Hegeman, A. D., Vestling, M. M., and Frey, P. A. (2000) Biochemistry 39, 13633-13640
19. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
20. Navaza, J. (1994) Acta Crystallogr. A50, 157-163
21. Roussel, A., Fontecilla-Camps, J. C., and Cambillau, C. (1990) Acta Cryst. A4, C66-C67
22. Tronrud, D. E., Ten Eyck, L. F., and Matthews, B. W. (1987) Acta Crystallogr. Sect. A 43, 489-501
23. Kabsch, W. (1988) J. Appl. Crystallogr. 21, 67-71
24. Kabsch, W. (1988) J. Appl. Crystallogr. 21, 916-924
25. Lee, B., and Richards, F. M. (1971) J. Mol. Biol. 55, 379-400
26. Hegeman, A. D., Gross, J. W., and Frey, P. A. (2001) Biochemistry 40, 6598-6610
27. Gross, J. W., Hegeman, A. D., Gerratana, B., and Frey, P. A. (2001) Biochemistry 40, 12497-12504
28. Hegeman, A. D., Gross, J. W., and Frey, P. A. (2002) Biochemistry 41, 2797-2804
29. Thoden, J. B., and Holden, H. M. (1998) Biochemistry 37, 11469-11477
30. Melo, A., Elliott, W. H., and Glaser, L. (1968) J. Biol. Chem. 243, 1467-1474
31. Gabriel, O., and Lindquist, L. C. (1968) J. Biol. Chem. 243, 1479-1484
32. Kleywegt, G. J., and Jones, T. A. (1993) Newsl. Prot. Crystallogr. 29, 26-28
33. Kleywegt, G. J., and Jones, T. A. (1994) Acta Crystallogr. Sect. D. 50, 178-185
34. Gerratana, B., Cleland, W. W., and Frey, P. A. (2001) Biochemistry 40, 9187-9195
35. March, J. (1985) Advanced Organic Chemistry, 3rd Ed., pp. 218-236, John Wiley and Sons, New York
36. Snipes, C. E., Brillinger, G. U., Sellers, L., Mascaro, L., and Floss, H. G. (1977) J. Biol. Chem. 252, 8113-8117
37. Charnock, S. J., Brown, I. E., Turkenburg, J. P., Black, G. W., and Davies, G. J. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 12067-12072
38. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
39. Thoden, J. B., Frey, P. A., and Holden, H. M. (1996) Biochemistry 35, 5137-5144