Use of YFP to study amyloid-β associated neurite alterations in live brain slices

Neurobiology of Aging

Volumn 24, Issue 8, 2003, Pages 1071-1077

  Brendza, Robert P ^a   Simmons, Kelly ^a   Bales, Kelly R ^b   Paul, Steven M ^b,c   Goldberg, Mark P ^a   Holtzman, David M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute slice preparation; Alzheimer's disease; Amyloid; Confocal microscopy; Fluorescent protein; Neurite; Neuritic dystrophy; Transgenic mice

Indexed keywords

AMYLOID BETA PROTEIN; BACTERIAL PROTEIN; PHOTOPROTEIN; YELLOW FLUORESCENT PROTEIN; YELLOW FLUORESCENT PROTEIN, BACTERIA;

ALZHEIMER DISEASE; ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BIOSYNTHESIS; BRAIN; BRAIN SLICE; CONFERENCE PAPER; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; DIFFUSION CHAMBER; DISEASE ASSOCIATION; GENETICS; INSTRUMENTATION; LASER MICROSCOPY; METABOLISM; METHODOLOGY; MODEL; MOUSE; NERVE CELL; NERVE DEGENERATION; NERVE FIBER; NERVE FIBER DEGENERATION; NEURITE; NONHUMAN; PATHOLOGY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENILE PLAQUE; SYNAPSE; TISSUE CULTURE; TRANSGENIC MOUSE;

EID: 0345708205     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2003.04.008     Document Type: Conference Paper

References (25)

1. Bales K.R., Verina T., Dodel R.C., Du Y., Altstiel L., Bender M.et al. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nat. Genet. 17(3):1997;263-264.
2. Borst J.G., Helmchen F., Sakmann B. Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapezoid body of the rat. J. Physiol. 489(Pt 3):1995;825-840.
3. Brendza R.P., O'brien C., Simmons K., McKeel D.W., Bales K.R., Paul S.M.et al. PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. J. Comp. Neurol. 456(4):2003;375-383.
4. Denk W., Svoboda K. Photon upmanship: why multiphoton imaging is more than a gimmick. Neuron. 18(3):1997;351-357.
5. Feng G., Mellor R.H., Bernstein M., Keller-Peck C., Nguyen Q.T., Wallace M.et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron. 28(1):2000;41-51.
6. Forsythe I.D. Direct patch recording from identified presynaptic terminals mediating glutamatergic EPSCs in the rat CNS, in vitro. J. Physiol. 479(Pt 3):1994;381-387.
7. Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C.et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature. 373(6514):1995;523-527.
8. Geiger J.R., Bischofberger J., Vida I., Frobe U., Pfitzinger S., Weber H.J.et al. Patch-clamp recording in brain slices with improved slicer technology. Pflugers Arch. 443(3):2002;491-501.
9. Geiger J.R., Jonas P. Dynamic control of presynaptic Ca(2+) inflow by fast-inactivating K(+) channels in hippocampal mossy fiber boutons. Neuron. 28(3):2000;927-939.
10. Golde T.E., Eckman C.B., Younkin S.G. Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease. Biochim. Biophys. Acta. 1502(1):2000;172-187.
11. Hartley D.M., Walsh D.M., Ye C.P., Diehl T., Vasquez S., Vassilev P.M.et al. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J. Neurosci. 19(20):1999;8876-8884.
12. Holtzman D.M., Bales K.R., Tenkova T., Fagan A.M., Parsadanian M., Sartorius L.J.et al. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 97(6):2000;2892-2897.
13. Irizarry M.C., Soriano F., McNamara M., Page K.J., Schenk D., Games D.et al. Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J. Neurosci. 17(18):1997;7053-7059.
14. Knowles R.B., Wyart C., Buldyrev S.V., Cruz L., Urbanc B., Hasselmo M.E.et al. Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 96(9):1999;5274-5279.
15. Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M.et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U.S.A. 95(11):1998;6448-6453.
16. Le R., Cruz L., Urbanc B., Knowles R.B., Hsiao-Ashe K., Duff K.et al. Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption. J. Neuropathol. Exp. Neurol. 60(8):2001;753-758.
17. Lorenzo A., Yankner B.A. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc. Natl. Acad. Sci. U.S.A. 91(25):1994;12243-12247.
18. Mainen ZF, Maletic-Savatic M, Shi SH, Hayashi Y, Malinow R, Svoboda K. Two-photon imaging in living brain slices. Methods 1999;18(2):231-9, 181.
19. Masliah E., Sisk A., Mallory M., Mucke L., Schenk D., Games D. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease. J. Neurosci. 16(18):1996;5795-5811.
20. Pike C.J., Burdick D., Walencewicz A.J., Glabe C.G., Cotman C.W. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13(4):1993;1676-1687.
21. Pike C.J., Walencewicz A.J., Glabe C.G., Cotman C.W. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563(1-2):1991;311-314.
22. Rice M.E. Use of ascorbate in the preparation and maintenance of brain slices. Methods. 18(2):1999;144-149.
23. Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81(2):2001;741-766.
24. Tekkok S.B., Goldberg M.P. Ampa/kainate receptor activation mediates hypoxic oligodendrocyte death and axonal injury in cerebral white matter. J. Neurosci. 21(12):2001;4237-4248.
25. Vickers J.C., Dickson T.C., Adlard P.A., Saunders H.L., King C.E., McCormack G. The cause of neuronal degeneration in Alzheimer's disease. Prog. Neurobiol. 60(2):2000;139-165.