-
1
-
-
0028589416
-
Experimental and clinical studies of cytokine gene modified tumor cells
-
Tepper, R. I., and J. J. Mule. 1994. Experimental and clinical studies of cytokine gene modified tumor cells. Hum. Gene Ther. 5:153.
-
(1994)
Hum. Gene Ther.
, vol.5
, pp. 153
-
-
Tepper, R.I.1
Mule, J.J.2
-
3
-
-
0029117106
-
Gene therapy for the medical oncologist
-
Blaese, M., Th. Blankenstein, M. Brenner, O. Cohen-Haguenauer, B. Gansbacher, B. Sorrentino, and T. Velu. 1995. Gene therapy for the medical oncologist. Eur. J. Cancer 31A:1531.
-
(1995)
Eur. J. Cancer
, vol.31 A
, pp. 1531
-
-
Blaese, M.1
Blankenstein, Th.2
Brenner, M.3
Cohen-Haguenauer, O.4
Gansbacher, B.5
Sorrentino, B.6
Velu, T.7
-
4
-
-
0027407938
-
Mechanisms of rejection induced by tumor cell targeted gene transfer of interleukin-2, interleukin-4, interleukin-7, tumor necrosis factor or interferon-gamma
-
Hock, H., M. Dorsch, U. Kunzendorf, Z. Qin, T. Diamantstein, and T. Blankenstein. 1993. Mechanisms of rejection induced by tumor cell targeted gene transfer of interleukin-2, interleukin-4, interleukin-7, tumor necrosis factor or interferon-gamma. Proc. Natl. Acad. Sci. USA 90:2774.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2774
-
-
Hock, H.1
Dorsch, M.2
Kunzendorf, U.3
Qin, Z.4
Diamantstein, T.5
Blankenstein, T.6
-
5
-
-
0027394642
-
Vaccinations with tumor cells genetically engineered to produce different cytokines: Effectivity not superior to a classical adjuvant
-
Hock, H., M. Dorsch, U. Kunzendorf, K. Überla, Z. Qin, T. Diamantstein, and T. Blankenstein. 1993. Vaccinations with tumor cells genetically engineered to produce different cytokines: effectivity not superior to a classical adjuvant. Cancer Res. 53:714.
-
(1993)
Cancer Res.
, vol.53
, pp. 714
-
-
Hock, H.1
Dorsch, M.2
Kunzendorf, U.3
Überla, K.4
Qin, Z.5
Diamantstein, T.6
Blankenstein, T.7
-
6
-
-
0027078670
-
Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
-
Chen, L., S. Ashe, W. A. Brady, I. Hellström, K. E. Hellström, J. A. Ledbetter, P. McGowan, and P. S. Linsley. 1992. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 71:1093.
-
(1992)
Cell
, vol.71
, pp. 1093
-
-
Chen, L.1
Ashe, S.2
Brady, W.A.3
Hellström, I.4
Hellström, K.E.5
Ledbetter, J.A.6
McGowan, P.7
Linsley, P.S.8
-
7
-
-
0027392843
-
+ T cells by B7-transfected melanoma cells
-
+ T cells by B7-transfected melanoma cells. Science 259:368.
-
(1993)
Science
, vol.259
, pp. 368
-
-
Townsend, S.E.1
Allison, J.P.2
-
8
-
-
0029914307
-
Coexpression of interleukin 4 and B7.1 in murine tumor cells leads to improved tumor rejection and vaccine effect compared to single gene transfectants and a classical adjuvant
-
Cayeux, S., C. Beck, B. Dörken, and T. Blankenstein. 1996. Coexpression of interleukin 4 and B7.1 in murine tumor cells leads to improved tumor rejection and vaccine effect compared to single gene transfectants and a classical adjuvant. Hum. Gene Ther. 7:525.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 525
-
-
Cayeux, S.1
Beck, C.2
Dörken, B.3
Blankenstein, T.4
-
9
-
-
0029101821
-
Tumor cells cotransfected with interleukin 7 and B7.1 genes induce CD25 and CD28 on tumor infiltrating lymphocytes and are strong vaccines
-
Cayeux, S., C. Beck, A. Aicher, B. Dörken, and Th. Blankenstein. 1995. Tumor cells cotransfected with interleukin 7 and B7.1 genes induce CD25 and CD28 on tumor infiltrating lymphocytes and are strong vaccines. Eur. J. Immunol. 25: 2325.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 2325
-
-
Cayeux, S.1
Beck, C.2
Aicher, A.3
Dörken, B.4
Blankenstein, Th.5
-
10
-
-
0028867445
-
B7.1 amplifies the response to interleukin-2-secreting tumor vaccines in vivo, but fails to induce a response by naive cells in vitro
-
Salvadori, S., B. Gansbacher, I. Wernick, S. Tirelli, and K. Zier. 1995. B7.1 amplifies the response to interleukin-2-secreting tumor vaccines in vivo, but fails to induce a response by naive cells in vitro. Hum. Gene Ther. 6:1299.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1299
-
-
Salvadori, S.1
Gansbacher, B.2
Wernick, I.3
Tirelli, S.4
Zier, K.5
-
11
-
-
0028877304
-
B7.1 and interleukin 12 synergistically induce effective antitumor immunity
-
Coughlin, C. M., M. Wysocka, H. L. Kurzawa, W. M. F. Lee, G. Trinchieri, and S. L. Eck. 1995. B7.1 and interleukin 12 synergistically induce effective antitumor immunity. Cancer Res. 55:4980.
-
(1995)
Cancer Res.
, vol.55
, pp. 4980
-
-
Coughlin, C.M.1
Wysocka, M.2
Kurzawa, H.L.3
Lee, W.M.F.4
Trinchieri, G.5
Eck, S.L.6
-
12
-
-
0017126775
-
Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
-
Bevan, M. J. 1976. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143:1283.
-
(1976)
J. Exp. Med.
, vol.143
, pp. 1283
-
-
Bevan, M.J.1
-
13
-
-
0028179056
-
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
-
Huang, A. Y. C., P. Golumbek, M. Ahmadzadeh, E. Jaffee, D. Pardoll, and H. Levitsky. 1994. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science 264:961.
-
(1994)
Science
, vol.264
, pp. 961
-
-
Huang, A.Y.C.1
Golumbek, P.2
Ahmadzadeh, M.3
Jaffee, E.4
Pardoll, D.5
Levitsky, H.6
-
14
-
-
0029864363
-
Does B7.1 expression confer antigen-presenting cell capacity to tumors in vivo?
-
Huang, A. Y. C., A. T. Brace, D. Pardoll, and H. Levitsky. 1996. Does B7.1 expression confer antigen-presenting cell capacity to tumors in vivo? J. Exp. Med. 183:769.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 769
-
-
Huang, A.Y.C.1
Brace, A.T.2
Pardoll, D.3
Levitsky, H.4
-
15
-
-
0029867486
-
Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogeneous antigen by tumor-infiltrating antigen-presenting cells
-
Pulaski, B. A., K.-Y. Yeh, N. Shastri, K. M. Maltby, D. P. Penney, E. M. Lord, and J. G. Frelinger. 1996. Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogeneous antigen by tumor-infiltrating antigen-presenting cells. Proc. Natl. Acad. Sci. USA 93:3669.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3669
-
-
Pulaski, B.A.1
Yeh, K.-Y.2
Shastri, N.3
Maltby, K.M.4
Penney, D.P.5
Lord, E.M.6
Frelinger, J.G.7
-
16
-
-
0029920908
-
+ cytolytic T lymphocytes
-
+ cytolytic T lymphocytes. J. Exp. Med. 183:791.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 791
-
-
Johnston, J.V.1
Malacko, A.R.2
Mizuno, M.T.3
McGowan, P.4
Hellström, I.5
Hellström, K.E.6
Marquardt, H.7
Chen, L.8
-
17
-
-
0027433264
-
Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I MHC-restricted CTL epitopes
-
Gavin, M. A., M. J. Gilbert, S. R. Riddell, P. D. Greenberg, and M. J. Bevan. 1993. Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I MHC-restricted CTL epitopes. J. Immunol. 151:3971.
-
(1993)
J. Immunol.
, vol.151
, pp. 3971
-
-
Gavin, M.A.1
Gilbert, M.J.2
Riddell, S.R.3
Greenberg, P.D.4
Bevan, M.J.5
-
18
-
-
0030064031
-
Medullary thymic epithelial cells induce tolerance to intracellular proteins
-
Oukka, M., M. Cohen-Tannoudji, Y. Tanaka, C. Babinet, and K. Kosmatopoulos. 1996. Medullary thymic epithelial cells induce tolerance to intracellular proteins. J. Immunol. 156:968.
-
(1996)
J. Immunol.
, vol.156
, pp. 968
-
-
Oukka, M.1
Cohen-Tannoudji, M.2
Tanaka, Y.3
Babinet, C.4
Kosmatopoulos, K.5
-
19
-
-
0025602333
-
Lack of tumorigenicity of interleukin 4 autocrine growing cells seems related to the anti-tumor function of interleukin 4
-
Li, W., T. Diamantstein, and T. Blankenstein. 1990. Lack of tumorigenicity of interleukin 4 autocrine growing cells seems related to the anti-tumor function of interleukin 4. Mol. Immunol. 27:1331.
-
(1990)
Mol. Immunol.
, vol.27
, pp. 1331
-
-
Li, W.1
Diamantstein, T.2
Blankenstein, T.3
-
20
-
-
0000276084
-
Autocrine stimulation after transfer of the granulocyte-macrophage-colony-stimulating-factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway
-
Laker, C., C. Stocking, U. Bergholz, N. Hess, J. F. De-Lamarter, and W. Ostertag. 1987. Autocrine stimulation after transfer of the granulocyte-macrophage-colony-stimulating-factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway. Proc. Natl. Acad. Sci. USA 84:8458.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8458
-
-
Laker, C.1
Stocking, C.2
Bergholz, U.3
Hess, N.4
De-Lamarter, J.F.5
Ostertag, W.6
-
21
-
-
0025361098
-
Murine interleukin 7 (IL-7) receptor: Characterization on an IL-7-dependent cell line
-
Park, L. S., D. J. Friend, A. E. Schmierer, S. K. Dower, and A. E. Namen. 1990. Murine interleukin 7 (IL-7) receptor: characterization on an IL-7-dependent cell line. J. Exp. Med. 171:1073.
-
(1990)
J. Exp. Med.
, vol.171
, pp. 1073
-
-
Park, L.S.1
Friend, D.J.2
Schmierer, A.E.3
Dower, S.K.4
Namen, A.E.5
-
22
-
-
0027087331
-
Costimulation of T lymphocytes: The role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy
-
Schwartz, R. H. 1992. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71: 1065.
-
(1992)
Cell
, vol.71
, pp. 1065
-
-
Schwartz, R.H.1
-
23
-
-
0025095664
-
Interleukin 2 production by tumor cells bypasses T helper function in the generation of an antitumor response
-
Fearon, E. R., D. M. Pardoll, T. Itaya, P. Golumbek, H. I. Levitsky, J. W. Simons, H. Karasuyama, B. Vogelstein, and P. Frost. 1990. Interleukin 2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell 60:397.
-
(1990)
Cell
, vol.60
, pp. 397
-
-
Fearon, E.R.1
Pardoll, D.M.2
Itaya, T.3
Golumbek, P.4
Levitsky, H.I.5
Simons, J.W.6
Karasuyama, H.7
Vogelstein, B.8
Frost, P.9
-
24
-
-
0028861977
-
A reassessment of the role of B7-1 expression in tumor rejection
-
Wu, L. C., A. Y. C. Huang, E. M. Jaffee, H. I. Levitsky, and D. M. Pardoll. 1995. A reassessment of the role of B7-1 expression in tumor rejection. J. Exp. Med. 182:1415.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1415
-
-
Wu, L.C.1
Huang, A.Y.C.2
Jaffee, E.M.3
Levitsky, H.I.4
Pardoll, D.M.5
-
26
-
-
0030057218
-
T cell activation determined by T cell receptor number and tunable thresholds
-
Viola, A., and A. Lanzavecchia. 1996. T cell activation determined by T cell receptor number and tunable thresholds. Science 273:104.
-
(1996)
Science
, vol.273
, pp. 104
-
-
Viola, A.1
Lanzavecchia, A.2
-
27
-
-
0028809507
-
Expression of costimulatory molecules B7.1 (CD80), B7.2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
-
Windhagen, A., J. Newcombe, F. Dangond, C. Strand, M. N. Woodroofe, M. L. Cuzner, and D. A. Hafler. 1995. Expression of costimulatory molecules B7.1 (CD80), B7.2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J. Exp. Med. 182:1985.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1985
-
-
Windhagen, A.1
Newcombe, J.2
Dangond, F.3
Strand, C.4
Woodroofe, M.N.5
Cuzner, M.L.6
Hafler, D.A.7
-
28
-
-
0027258119
-
Deficient antigen presentation by Langerhans cells from athymic (nu/nu) mice
-
Grabbe, S., R. L. Gallo, A. Lindgren, and R. D. Granstein. 1993. Deficient antigen presentation by Langerhans cells from athymic (nu/nu) mice. J. Immunol. 151:3430.
-
(1993)
J. Immunol.
, vol.151
, pp. 3430
-
-
Grabbe, S.1
Gallo, R.L.2
Lindgren, A.3
Granstein, R.D.4
-
29
-
-
0027517856
-
Interleukin-7 is a potent co-stimulus of the adhesion pathway involving CD2 and CD28 molecules
-
Costello, R., H. Brailly, F. Mallet, C. Mawas, and D. Olive. 1993. Interleukin-7 is a potent co-stimulus of the adhesion pathway involving CD2 and CD28 molecules. Immunology 80:451.
-
(1993)
Immunology
, vol.80
, pp. 451
-
-
Costello, R.1
Brailly, H.2
Mallet, F.3
Mawas, C.4
Olive, D.5
-
30
-
-
0027500568
-
Granulocytes, macrophages, and dendritic cells arise from a common major histocompalibility complex class II-negative progenitor in mouse bone marrow
-
Inaba, K., M. Inaba, M. Deguchi, K. Hagi, R. Yasumizu, S. Ikehara, and S. Muramatsu. 1993. Granulocytes, macrophages, and dendritic cells arise from a common major histocompalibility complex class II-negative progenitor in mouse bone marrow. Proc. Natl. Acad. Sci. USA 90:3038.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3038
-
-
Inaba, K.1
Inaba, M.2
Deguchi, M.3
Hagi, K.4
Yasumizu, R.5
Ikehara, S.6
Muramatsu, S.7
-
31
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
-
Dranoff, G., E. Jaffee, A. Lazenby, P. Golumbek, H. Levitsky, K. Brose, V. Jackson, H. Hamada, D. Pardoll, and R. C. Mulligan. 1993. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad Sci. USA 90:3539.
-
(1993)
Proc. Natl. Acad Sci. USA
, vol.90
, pp. 3539
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Levitsky, H.5
Brose, K.6
Jackson, V.7
Hamada, H.8
Pardoll, D.9
Mulligan, R.C.10
-
32
-
-
0028646191
-
Specificity and longetivity of antitumor immune responses induced by B7-transfected tumors
-
Townsend, S. E., F. W. Su, J. M. Atherton, and J. P. Allison. 1994. Specificity and longetivity of antitumor immune responses induced by B7-transfected tumors. Cancer Res. 54:6477.
-
(1994)
Cancer Res.
, vol.54
, pp. 6477
-
-
Townsend, S.E.1
Su, F.W.2
Atherton, J.M.3
Allison, J.P.4
-
33
-
-
0028036933
-
Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor α, granulocyte-macrophage colony-stimulating factor, and γ-interferon gene or admixed with conventional adjuvants
-
Allione, A., M. Consalvo, P. Nanni, P. L. Lollini, F. Cavallo, M. Giovarelli, M. Forni, A. Gulino, M. P. Colombo, P. Dellabona, H. Hock, Th. Blankenstein, F. M. Rosenthal, B. Gansbacher, M. C. Bosco, T. Musso, L. Gusella, and G. Forni. 1994. Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor α, granulocyte-macrophage colony-stimulating factor, and γ-interferon gene or admixed with conventional adjuvants. Cancer Res. 54:6022.
-
(1994)
Cancer Res.
, vol.54
, pp. 6022
-
-
Allione, A.1
Consalvo, M.2
Nanni, P.3
Lollini, P.L.4
Cavallo, F.5
Giovarelli, M.6
Forni, M.7
Gulino, A.8
Colombo, M.P.9
Dellabona, P.10
Hock, H.11
Blankenstein, Th.12
Rosenthal, F.M.13
Gansbacher, B.14
Bosco, M.C.15
Musso, T.16
Gusella, L.17
Forni, G.18
|