A PDZ-containing scaffold related to the dystrophin complex at the basolateral membrane of epithelial cells

Journal of Cell Biology

Volumn 145, Issue 2, 2000, Pages 391-402

  Kachinsky, Amy M ^a   Froehner, Stanley C ^a   Milgram, Sharon L ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Dystrobrevin; Green fluorescent protein; Madin Darby canine kidney; Syntrophin; Utrophin

Indexed keywords

DYSTROPHIN; GREEN FLUORESCENT PROTEIN; NITRIC OXIDE SYNTHASE; UTROPHIN;

ANIMAL CELL; ARTICLE; BASOLATERAL MEMBRANE; CARBOXY TERMINAL SEQUENCE; CELL POLARITY; EPITHELIUM CELL; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; CELL MEMBRANE; CELL POLARITY; CYTOSKELETAL PROTEINS; DOGS; DYSTROPHIN-ASSOCIATED PROTEINS; EPITHELIAL CELLS; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; MUSCLE PROTEINS; NEUROPEPTIDES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TRANSFECTION; UTROPHIN;

ANIMALIA;

EID: 0345593814     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.145.2.391     Document Type: Article

References (118)

1. Adams, M.E., M.H. Butler, T.M. Dwyer, M.F. Peters, A.A. Murnane, and S.C. Froehner. 1993. Two forms of mouse syntrophin, a 58-kD dystrophin-associated protein, differ in primary structure and tissue distribution. Neuron. 11: 531-540.
2. Adams, M.E., T.M. Dwyer, L.L. Dowler, R.A. White, and S.C. Froehner. 1995. Mouse al-and β2-syntrophin gene structure, chromosome localization, and homology with a discs large domain. J. Biol. Chem. 270:25859-25865.
3. Ahn, A.H., and L.M. Kunkel. 1993. The structural and functional diversity of dystrophin. Nat. Genet. 3:81-93.
4. Ahn, A.H., and L.M. Kunkel. 1995. Syntrophin binds to an alternatively spliced exon of dystrophin. J. Cell Biol. 128:363-371.
5. Ahn, A.H., M. Yoshida, M.S. Anderson, CA. Feener, S. Selig, Y. Hagiwara, E. Ozawa, and L.M. Kunkel. 1994. Cloning of human basic Al, a distinct 59-kD dystrophin-associated protein encoded on chromosome 8q23-24. Proc. Nail. Acad. Sci. USA. 91:4446-4450.
6. Ahn, A., H.C.A. Feener, E. Gussoni, M. Yoshida, E. Ozawa, and L.M. Kunkel. 1996. The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives. J. Biol. Chem. 271:2724-2730.
7. Balasubramian, S., E.T. Fung, and R.L. Huganir. 1998. Characterization of the tyrosine phosphorylation and distribution of dystrobrevin isoforms. FEBS Lett. 432:133-140.
8. Beatch, M., L.A. Jesaitis, W.J. Gallin, D.A. Goodenough, and B.R. Stevenson. 1996. The tight junction protein ZO-2 contains three PDZ (PSD-95/Discs-Large/ZO-1) domains and an alternatively spliced region. J. Biol. Chem. 271: 25723-25726.
9. Bewick, G.S., L.B.V. Nicholson, C. Young, E. O'Donnell, and C.R. Slater. 1992. Different distributions of dystrophin and related proteins at nerve muscle junctions. Neuroreport. 3:857-860.
10. Blake, D.J., R. Nawrotzki, M.F. Peters, S.C. Froehner, and K.E. Davies. 1996. Isoform diversity of dystrobrevin, the murine 87-kD postsynaptic protein. J. Biol. Chem. 271:7802-7810.
11. Blake, D.J., R. Nawrotzki, N.Y. Loh, D.C. Górecki, and K.E. Davies. 1998. β-dystrobrevin, a member of the dystrophin-related protein family. Proc. Natl. Acad. Sci. USA. 95:241-246.
12. Brenman, J.E., D.S. Chao, S.H. Gee, A.W. McGee, S.E. Craven, D.R. Santillano, Z. Wu, F. Huang, H. Xia, M.F. Peters, et al. 1996. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and α1-syntrophin mediated by PDZ domains. Cell. 84:757-767.
13. Campanelli, J.T., S.L. Roberds, K.P. Campbell, and R.H. Scheller. 1994. A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering. Cell. 77:663-674.
14. Caplan, M.J. 1997. Membrane polarity in epithelial cell: protein sorting and establishment of polarized domains. Am. J. Physiol. 272:F425-F429.
15. r protein associated with acetytcholine receptors in Torpedo electric organ and vertebrate skeletal muscle. J. Cell Biol. 109:1753-1764.
16. Cho, K., C.A. Hunt, and M.B. Kennedy. 1992. The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein. Neuron. 9:929-942.
17. Cohen, A.R., D.F. Wood, S.M. Marfatia, Z. Walther, A.H. Chrishti, and J.M. Anderson. 1998. Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells. J. Cell Biol. 142: 129-138.
18. Colledge, M., and S.C. Froehner. 1998. Signals mediating ion channel clustering at the neuromuscular junction. Curr. Opin. Neurobiol. 8:357-363.
19. Dong, H., R.J. O'Brien, E.T. Fung, A.A. Lanahan, P.F. Worley, and R.L. Huganir. 1997. GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature. 386:279-284.
20. Drubin, D.G., and W.J. Nelson. 1996. Origins of cell polarity. Cell. 84:335-344.
21. Durbeej, M., E. Larsson, O. Ibraghimov-Beskrovnaya, S.L. Roberds, K.P. Campbell, and P. Ekblom. 1995. Nonmuscle α-dystroglycan is involved in epithelial development. J. Cell Biol. 130:79-91.
22. Durbeej, M., D. Jung, T. Hjalt, K.P. Campbell, and P. Ekblom. 1997. Transient expression of Dp140, a product of the Duchenne muscular dystrophy locus, during kidney tubulogenesis. Dev. Biol. 181:156-167.
23. Durbeej, M., M.D. Henry, M. Ferletta, K.P. Campbell, and P. Ekblom. 1998. Distribution of dystroglycan in normal adult mouse tissues. J. Histochem. Cytochem. 46:449-457.
24. Dwyer, T.M., and S.C. Froehner. 1995. Direct binding of Torpedo syntrophin to dystrophin and the 87-kD dystrophin homologue. FEBS Lett. 375:91-94.
25. Ekblom, M., G. Klein, G. Mugrauer, L. Fecker, R. Deutzmann, R. Timpl, and P. Ekblom. 1990. Transient and locally restricted expression of laminin A chain mRNA by developing epithelial cells during kidney organogenesis. Cell. 60:337-346.
26. Ervasti, J.M., and K.P. Campbell. 1991. Membrane specialization of the dystrophin-glycoprotein complex. Cell. 66:1121-1131.
27. Ervasti, J.M., and K.P. Campbell. 1993. A role for the dystrophin-glycoprotein complex as a transmembrane link between laminin and actin. J. Cell Biol. 122:809-823.
28. Fanning, A.S., B.J. Jameson, L.A. Jesaitis, and J.M. Anderson. 1998. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J. Biol. Chem. 273:29745-29753.
29. 125I-labeled α-bungarotoxin binding in mouse motor endplates. Proc. Natl. Acad. Sci. USA. 71:1376-1378.
30. + channels and ankyrin in neuromuscular junctions is complementary to that of acetylcholine receptors and the 43-kD protein. Neuron. 3:163-175.
31. Froehner, S.C., A.A. Murnane, M. Tobler, H.B. Peng, and R. Sealock. 1987. A postsynaptic M, 58,000 (58K) protein concentrated at acetylcholine receptor-rich sites in Torpedo electroplaques and skeletal muscle. J. Cell Biol. 104: 1633-1646.
32. Furuse, M., M. Itoh, T. Hirase, A. Nagafuchi, S. Yonemura, S. Tsukita, and S. Tsukita. 1994. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol. 127: 1617-1626.
33. Gee, S.H., R.W. Blacher, P.J. Douville, P.R. Provost, P.D. Yurchenco, and S. Carbonetto. 1993. Laminin-binding protein 120 from brain is closely related to the dystrophin-associated glycoprotein, dystroglycan, and binds with high affinity to the major heparan binding domain of laminin. J. Biol. Chem. 268: 14972-14978.
34. Gee, S.H., F. Montanaro, M.H. Lindenbaum, and S. Carbonetto. 1994. Dystroglycan-α, a dystrophin-associated glycoprotein, is a functional agrin receptor. Cell. 77:675-686.
35. Gee, S.H., R. Madhavan, S.R. Levinson, J.H. Caldwell, R. Sealock, and S.C. Froehner. 1998. Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins. J. Neurosci. 18:128-137.
36. Gesemann, M., A. Brancacio, B. Schumacher, and M.A. Ruegg. 1998. Agrin is a high-affinity binding protein of dystroglycan in non-muscle tissue. J. Biol. Chem. 273:600-605.
37. Giloh, H., and J.W. Sedat. 1982. Fluorescence microscopy: reduced photobleaching of rhodamine and fluorescein protein conjugates by n-propyl gallate. Science. 217:1252-1255.
38. Grindstaff, K.K., C. Yeaman, N. Anandasabapathy, S. Hsu, E. Rodriguez-Boulan, R.H. Scheller, and W.J. Nelson. 1998. Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells. Cell. 93:731-740.
39. Gumbiner, B. 1987. Structure, biochemistry, and assembly of epithelial tight junctions. Am. J. Physiol. 253:C749-C758.
40. Gumbiner, B. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:345-357.
41. Haskins, J., L. Gu, E.S. Wittchen, J. Hibbard, and B.R. Stevenson. 1998. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J. Cell Biol. 141:199-208.
42. Hinck, L., I.S. Nathke, J. Papkoff, and W.J. Nelson. 1994. Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J. Cell Biol. 125:1327-1340.
43. Hough, C.D., D.F. Woods, S. Park, and P.J. Bryant. 1997. Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK discs large. Genes Dev. 11:3242-3253.
44. Hunziker, W., and C. Fumey. 1994. A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells. EMBO (Eur. Mol. Biol. Organ.) J. 13:2963-2967.
45. Ibraghimov-Beskrovnaya, O., J.M. Ervasti, C.J. Leveille, C.A. Slaughter, S.W. Sernett, and K.P. Campbell. 1992. Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix. Nature. 355:696-702,
46. Izumi, Y., T. Hirose, Y. Tamai, S. Hirai, Y. Nagashima, T. Fujimoto, Y. Tabuse, K.J. Kemphues, and S. Ohno. 1998. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J. Cell Biol. 143: 95-106.
47. Jordan, C., B. Puschel, R. Koob, and D. Drenckhahn. 1995. Identification of a binding motif for ankyrin on the alpha-subunit of Na+,K(+) ATPase. J. Biol. Chem. 270:29971-29975.
48. Jung, D., B. Yang, J. Meyer, J.S. Chamberlain, and K.P. Campbell. 1995. Identification and characterization of the dystrophin anchoring site on β-dystroglycan. J. Biol. Chem. 270:27305-27310.
49. Khurana, T.S., E.P. Hoffman, and L.M. Kunkel. 1990. Identification of a chromosome 6-encoded dystrophin-related protein. J. Biol. Chem. 265:16717-16720.
50. Kim, E., K.O. Cho, A. Rothschild, and M. Sheng. 1996. Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins. Neuron. 17:103-113.
51. Kim, S.K. 1997. Polarized signaling: basolateral receptor localization in epithelial cells by PDZ-containing proteins. Curr. Opin. Cell Biol. 9:853-859.
52. Kim, T.W., K. Wu, J.L. Xu, and I.B. Black. 1992. Detection of dystrophin in the postsynaptic density of rat brain and deficiency in a mouse model of Duchenne muscular dystrophy. Proc. Natl. Acad. Sci. USA. 89:11642-11644.
53. Klein, G., M. Langegger, R. Timpl, and P. Ekblom. 1988. Role of laminin A chain in the development of epithelial cell polarity. Cell. 55:331-341.
54. Koenig, M., and L.M. Kunkel. 1990. Detailed analysis of the repeat domain of dystrophin reveals four potential hinge segments that may confer flexibility. J. Biol. Chem. 265:4560-4566.
55. Koenig, M., A.P. Monaco, and L.M. Kunkel. 1988. The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein. Cell. 53:219-228.
56. Kornau, H., L.T. Schenker, M.B. Kennedy, and P.H. Seeburg. 1995. Domain interaction between NMDA receptor subunits and the postsynaptic protein PSD-95. Science. 269:1737-1739.
57. Kornau, H., P.H. Seeburg, and M.B. Kennedy. 1997. Interaction of ion channel and receptors with PDZ domain proteins. Curr Opin. Neurobiol. 7:368-373.
58. r 58,000 dystrophin-associated protein (syntrophin). J. Biol. Chem. 269:2870-2876.
59. Ktistakis, N.T., D. Thomas, and M.G. Roth. 1990. Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins. J. Cell Biol. 111:1393-1407.
60. Li, Z., M.W. Chapleau, J.N. Bates, K. Bielefeldt, H.-C. Lee, and A.F. Abboud. 1998. Nitric oxide as an autocrine regulator of sodium currents in baroreceptor neurons. Neuron. 20:1039-1049.
61. Lidov, H.G., and L.M. Kunkel. 1998. Dystrophin and Dp140 in the adult rodent kidney. Lab. Invest. 78:1543-1551.
62. Lidov, H.G., T.J. Beyers, S.C. Watkins, and L.M. Kunkel. 1990. Association of dystrophin to postsynaptic regions of the central nervous system cortical neurons. Nature. 348:725-728.
63. Love, D.R., G.E. Morris, J.M. Ellis, U. Fairbrother, R.F. Marsden, J.F. Bloomfield, Y.H. Edwards, C.P. Slater, D.J. Parry, and K.E. Davies. 1991. Tissue distribution of the dystrophin-related gene product and expression in the mdx and dy mouse. Proc. Natl. Acad. Sci. USA. 88:3243-3247.
64. Lue, R.A., E. Brandin, E.P. Chan, and D. Branton. 1996. Two independent domains of hDLG are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain. J. Cell Biol. 135:1125-1137.
65. Madhavan, R., and H.W. Jarrett. 1995. Interactions between dystrophin glycoprotein complex proteins. Biochemistry. 34:12204-12209.
66. Mandai, K., H. Nakanishi, A. Satoh, K. Takahashi, H. Nishioka, A. Mizoguchi, and Y. Takai. 1999. Ponsin/SH3P12: an 1-afadin-and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions. J. Cell Biol. 144:1001-1018.
67. Matter, K., E.M. Yamamoto, and I. Mellman. 1994. Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells. J. Cell Biol. 126:991-1004.
68. Montanaro, F., S. Carbonetlo, K.P. Campbell, and M. Lindenbaum. 1995. Dystroglycan expression in the wild type and mdx mouse neural retina: synaptic colocalization with dystrophin, dystrophin-related protein, but not laminin. J. Neurosci. Res 45:528-538.
69. Montell, C. 1998. TRP trapped in fly signaling web. Curr. Opin. Neurobiol. 8:389-397.
70. Morris, G.E., S.G. Sedgwick, J.M. Ellis, J.S. Chamberlain, and N.T. Man. 1998. An epitope structure for the C-terminal domain of dystrophin and utrophin. Biochemistry. 37:11117-11127.
71. Mover, B.D., J. Loffing, E.M. Schwiebert, D. Loffing-Cueni, P.A. Halpin, K.H. Karlson, I.I. Ismailov, W.B. Guggino, G.M. Langford, and B.A. Stanton. 1998. Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in Madin-Darby canine kidney cells. J. Biol. Chem. 273:21759-21768.
72. Nagel, W., P. Schilcher, L. Zeitlmann, and W. Kolanus. 1998. The PH domain and the polybasic c domain of cytohesin-1 cooperate specifically in plasma membrane association and cellular function. Mol. Biol. Cell. 9:1981-1994.
73. Nathke, I.S., L. Hinck, J.R. Swedlow, J. Papkoff, and W.J. Nelson. 1994. Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells. J. Cell Biol. 125:1341-1352.
74. +)ATPase and implications for the organization of membrane domains in polarized cells. Nature. 328:533-536.
75. Nguyen, T.M., J.M. Ellis, D.R. Love, K.E. Davies, K.C. Gatter, G. Dickson, and G.E. Morris, 1991. Localization of the DMDL gene-encoded dystrophin-related protein using a panel of nineteen monoclonal antibodies: presence at neuromuscular junctions, in the sarcolemma of dystrophic muscle, in vascular and other smooth muscles, and in proliferating brain cell lines. J. Cell Biol. 115:1695-1700.
76. Ohlendieck, K., J.M. Ervasti, J.B. Snook, and K.P. Campbell. 1991a. Dystrophin-glycoprotein complex is highly enriched in isolated skeletal muscle sarcolemma. J. Cell Biol. 112:135-148.
77. Ohlendieck, K., J.M. Ervasti, K. Matsumura, S.D. Kahl, C.J. Leveille, and K.P. Campbell. 1991b. Dystrophin-related protein is localized to the neuromuscular junctions of adult skeletal muscle. Neuron. 7:499-508.
78. Pasternak, C., S. Wong, and E.L. Elson. 1995. Mechanical function of dystrophin in muscle cells. J. Cell Biol. 128:355-361.
79. Peters, M.F., N.R. Kramarcy, R. Sealock, and S.C. Froehner. 1994. β2-syntrophin: localization at the neuromuscular junction in skeletal muscle. Neuroreport. 5:1577-1580.
80. Peters, M.F., M.A. Adams, and S.C. Froehner. 1997a. Differential association of syntrophin pairs with the dystrophin complex. J. Cell Biol. 138:81-93.
81. Peters, M.F., K.F. O'Brien, H.M. Sadoulet-Puccio, L.M. Kunkel, M.A. Adams, and S.C. Froehner. 1997b. β-Dystrobrevin, a new member of the dystrophin family. Identification, cloning and protein associations. J. Biol. Chem 272: 31561-31569.
82. Peters, M.F., H.M. Sadoulet-Puccio, R.M. Grady, N.R. Kramarcy, L.M. Kunkel, J.R. Sanes, R. Sealock, and S.C. Froehner. 1998. Differential membrane localization and intermolecular associations of α-dystrobrevin isoforms in skeletal muscle. J. Cell Biol. 142:1269-1278.
83. Petrof, B.J., J.B. Shrager, H.H. Stedman, A.M. Kelly, and H.L. Sweeney. 1993. Dystrophin protects the sarcolemma from stresses developed during muscle contraction. Proc. Nail. Acad. Sci. USA. 90:3710-3714.
84. Puca, A.A., V. Nigro, G. Piluso, A. Belsito, S. Sampaplo, N. Quaderi, E. Rossi, G. Di Iorio, A. Ballabio, and B. Franco. 1998. Identification and characterization of a novel member of the dystrobrevin gene family. FEBS Lett. 425: 7-13.
85. Raats, C.J., M.A. Bakker, W. Hoch, W.P. Tamboer, A.J. Groffen, L.P. van der Heuvel, J.H. Berden, and J. van den Born. 1998. Differential expression of agrin in renal basement membranes as revealed by domain-specific antibodies. J. Biol. Chem. 273:17832-17838.
86. Roberts, R.G., T.C. Freeman, E. Kendall, D.L. Vetrie, A.K. Dixon, C. Shaw-Smith, Q. Bone, and M. Bobrow. 1996. Characterization of DRP2, a novel human dystrophin homologue. Nat. Genet. 13:223-226.
87. Rodriguez-Boulan, E., and W.J. Nelson. 1989. Morphogenesis of the polarized epithelial cell phenotype. Science. 245:718-725.
88. Rybakaova, I.N., K.J. Amann, and J.M. Ervasti. 1996. A new model for the interaction of dystrophin with F-actin. J. Cell Biol. 135:661-671.
89. Sadoulet-Puccio, H.M., T.S. Khurana, J.B. Cohen, and L.M. Kunkel. 1996. Cloning and characterization of the human homologue of a dystrophin associated phosphoprotein found at the Torpedo electric postsynaptic membrane. Hum. Mol. Genet. 5:489-496.
90. Sadoulet-Puccio, H.M., M. Rajala, and L.M. Kunkel. 1997. Dystrobrevin and dystrophin: an interaction through coiled-coil motifs. Proc. Natl. Acad. Sci. USA 94:12413-12418.
91. Satoh, A., H. Nakanishi, H. Obaishi, M. Wada, K. Takahashi, K. Satoh, K. Hirao, H. Nishioka, Y. Hata, A. Mizoguchi, et al. 1998. Neurabin-II/spinophilin. An actin filament-binding protein with one PDZ domain localized at cadherin-based cell-cell adhesion sites. J. Biol. Chem. 273:3470-3475.
92. Schmitz, F., M. Hooenbach, and D. Drenckhahn. 1993. Colocalization of retinal dystrophin and actin in postsynaptic dendrites of rod and cone photoreceptor synapses. Histochemistry. 100:473-479.
93. Schultz, J., U. Hoffmuller, G. Krause, J. Ashurst, M.J. Macias, P. Schmieder, J. Schneideer-Mergener, and H. Oshkinat. 1998. Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels. Nature Struct. Biol. 5:19-24.
94. r 43,000 protein and the acetylcholine receptor in Torpedo postsynaptic membranes using monoclonal antibodies. J. Cell Biol. 98:2239-2244.
95. Sealock, R., M.H. Butler, N.R. Kramarcy, K.-X. Gao, A.A. Murnane, K. Douville, and S.C. Froehner. 1991. Localization of dystrophin relative to acetylcholine receptor domains in electric tissue and adult and cultured skeletal muscle. J. Cell Biol. 113:1133-1144.
96. Shaw, G. 1996. The pleckstrin homology domain: an intriguing multifunctional protein module. Bioessays. 18:35-45.
97. Sheikh, H., and C.M. Isacke. 1996. A di-hydrophobic Leu-Val motif regulates the basolateral localization of CD44 in polarized Madin-Darby canine kidney epithelial cells. J. Biol. Chem. 271:12185-12190.
98. Sheng, M. 1996. PDZs and receptor/channel clustering: rounding up the latest suspects. Neuron. 17:575-578.
99. Short, D.B., K.W. Trotter, S.M. Reczek, A. Bretscher, R.C. Boucher, M.J. Stutts, and S.L. Milgram. 1998. An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton. J. Biol. Chem. 273:19797-19801.
100. Simons, K., and S.D. Fuller. 1985. Cell surface polarity in epithelia. Ann. Rev. Biochem. 1:243-288.
101. Simons, K., and A. Wandinger-Ness. 1990. Polarized sorting in epithelia. Cell. 62:207-210.
102. Simonsen, A., B. Bremnes, T.W. Nordeng, and O. Bakke. 1998. The leucinebased motif DDQxxLI is recognized both for internalization and basolateral sorting of invariant chain in MDCK cells. Eur. J. Cell Biol. 76:25-32.
103. Srivastava, S., P. Osten, F.S. Vilim, L. Khatri, G. Inman, B. States, C. Daly, S. DeSouza, R. Abagyan, J.G. Valtschanoff, et al. 1998. Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP. Neuron. 21:581-591.
104. Stevenson, B.R., J.D. Siliciano, M.S. Mooseker, and D.A. Goodenough. 1986. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a wide variety of epithelia. J. Cell Biol. 103:755-766.
105. Straub, V., and K.P. Campbell. 1997. Muscular dystrophies and the dystrophin-glycoprotein complex. Curr. Opin. Neurol. 10:168-175.
106. Suzuki, A., M. Yoshida, and E. Ozawa. 1995. Mammalian α1-and β1-syntrophin bind to the alternatively splice-prone region of the dystrophin COOH terminus. J. Cell Biol. 128:373-381.
107. Thevananther, S., A.H. Kolli, and P. Devarajan. 1997. Identification of a novel ankyrin isoform (AnkG190) in kidney and lung that associates with the plasma membrane and binds alpha-Na, K-ATPase. J. Biol. Chem. 273: 23952-23958.
108. Thomas, D.C., C.B. Brewer, and M.G. Roth. 1993. Vesicular stomatitis virus glycoprotein contains a dominant cytoplasmic basolateral sorting signal critically dependent upon a tyrosine. J. Biol. Chem. 268:3313-3320.
109. Tinsley, J.M., D.J. Blake, A. Roche, U. Fairbrother, J. Riss, B.C. Byth, A.E. Knight, J. Kendrick-Jones, G.K. Suthers, D.R. Love, et al. 1992. Primary structure of a dystrophin-related protein. Nature. 360:591-593.
110. Touhara, K., J. Inglese, J.A. Pritcher, G. Shaw, and R.J. Lefkowitz. 1994. Binding of G protein beta gamma-subunits to pleckstrin homology domains. J. Biol. Chem. 269:10217-10220.
111. Ullmer, C., K. Schmuck, A. Figge, and H. Lubbert. 1998. Cloning and characterization of MUPP1, a novel PDZ domain protein. FEBS Lett. 424:63-68.
112. Wandinger-Ness, A., M.K. Bennett, C. Antony, and K. Simons. 1990. Distinct transport vesicles mediate the delivery of the plasma membrane proteins to the apical and basolateral domains of MDCK cells. J. Cell Biol. 111:987-1000.
113. Wu, H., S.M. Reuver, S. Kuhlendahl, W.J. Chung, and C.C. Garner. 1998. Subcellular targeting and cytoskeletal attachment of SAP97 to the epithelial lateral membrane. J. Cell Sci. 111:2365-2376.
114. Xu, X.S., A. Choudhury, X. Li, and C. Montell. 1998. Coordination of an array of signaling proteins through homo-and heteromeric interactions between PDZ domains and target proteins. J. Cell Biol. 142:545-555.
115. Yang, B., D. Jung, J.A. Rafael, J.S. Chamberlain, and K.P. Campbell. 1994. Identification of α-syntrophin binding to syntrophin triplet, dystrophin, and utrophin. J. Biol. Chem. 270:4975-4978.
116. Yao, L., Y. Kawakami, and T. Kawakami. 1994. The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C. Proc. Natl. Acad. Sci. USA. 91:9175-9179.
117. Yap, A.S., W.M. Brieher, and B.M. Gumbiner. 1997. Molecular and functional analysis of cadherin-based adherens junctions. Annu. Rev. Cell Dev. Biol. 13: 119-146.
118. Yoshida, M., and E. Ozawa. 1990. Glycoprotein complex anchoring dystrophin to the sarcolemma. J. Biochem. 108:748-752.