Phosphodiesterase inhibitors suppress IL-12 production with microglia and T helper I development

Multiple Sclerosis

Volumn 9, Issue 6, 2003, Pages 574-578

  Suzumura, Akio ^a   Ito, Atsushi ^a   Mizuno, Tetsuya ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Antigen presentation; IL 12; Microglia; Phosphodiesterase inhibitor; T helper I

Indexed keywords

BETA INTERFERON; BUCLADESINE; FORSKOLIN; GAMMA INTERFERON; IBUDILAST; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; LOPRINONE; MESSENGER RNA; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PHOSPHODIESTERASE INHIBITOR; PROTEIN P35; PROTEIN P40; PROTEIN P70;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CELL MATURATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; LYMPHOCYTE DIFFERENTIATION; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGEN-PRESENTING CELLS; BUCLADESINE; CELL DIFFERENTIATION; CELLS, CULTURED; DRUG SYNERGISM; GENE EXPRESSION; INTERFERON-BETA; INTERLEUKIN-12; MICE; MICE, INBRED C57BL; MICROGLIA; PHOSPHODIESTERASE INHIBITORS; PYRIDINES; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0345392549     PISSN: 13524585     EISSN: None     Source Type: Journal    
DOI: 10.1191/1352458503ms970oa     Document Type: Article

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