Identification of Novel Recognition Motifs and Regulatory Targets for the Yeast Actin-regulating Kinase Prk1p

Molecular Biology of the Cell

Volumn 14, Issue 12, 2003, Pages 4871-4884

  Huang, Bo ^a   Zeng, Guisheng ^a   Ng, Alvin Y J ^a   Cai, Mingjie ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CONTROLLED STUDY; CYTOSKELETON; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENOTYPE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; YEAST;

ACTINS; CELL POLARITY; CYTOSKELETON; FUNGAL PROTEINS; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0345306591     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E03-06-0362     Document Type: Article

References (41)

1. Adams, A.E., and Pringle, J.R. (1984). Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae. J. Cell Biol. 98, 934-945.
2. Adams, A.E., and Pringle, J.R. (1991). Staining of actin with fluorochrome-conjugated phalloidin. Methods Enzymol. 194, 729-731.
3. Aguilar, R.C., Watson, H.A., and Wendland, B. (2003). The yeast Epsin Ent1 is recruited to membranes through multiple independent interactions. J. Biol. Chem. 278, 10737-10743.
4. Chang, F., and Peter, M. (2003). Yeasts make their mark. Nat. Cell Biol. 5, 294-299.
5. Chang, J.S., Henry, K., Wolf, B.L., Geli, M., and Lemmon, S.K. (2002). Protein phosphatase-1 binding to scd5p is important for regulation of actin organization and endocytosis in yeast. J. Biol. Chem. 277, 48002-48008.
6. Conner, S.D., and Schmid, S.L. (2002). Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis. J. Cell Biol. 156, 921-929.
7. Cope, M.J., Yang, S., Shang, C., and Drubin, D.G. (1999). Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast. J. Cell Biol. 144, 1203-1218.
8. Cormack, B. (1997). Directed mutagenesis using the polymerase chain reaction. In: Current Protocols in Molecular Biology, vol. 1, ed. F.M. Ausubel, R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, and K. Struhl, New York: John Wiley & Sons, 8.5.1-8.5.10.
9. Davis, N.G., Horecka, J.L., and Sprague, G.F., Jr. (1993). Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J. Cell Biol. 122, 53-65.
10. Dulic, V., Egerton, M., Elguindi, I., Raths, S., Singer, B., and Riezman, H. (1991). Yeast endocytosis assays. Methods Enzymol. 194, 697-710.
11. Duncan, M.C., Cope, M.J., Goode, B.L., Wendland, B., and Drubin, D.G. (2001). Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex. Nat. Cell Biol. 3, 687-690.
12. Fujiwara, T., Tanaka, K., Mino, A., Kikyo, M., Takahashi, K., Shimizu, K., and Takai, Y. (1998). Rho1p-Bni1p-Spa2p interactions: implication in localization of Bni1p at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae. Mol. Biol. Cell 9, 1221-1233.
13. Geli, M.I., and Riezman, H. (1998). Endocytic internalization in yeast and animal cells: similar and different. J. Cell Sci. 111, 1031-1037.
14. Gourlay, C.W., Dewar, H., Warren, D.T., Costa, R., Satish, N., and Ayscough, K.R. (2003). An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast. J. Cell Sci. 116, 2551-2564.
15. Guex, N., and Peitsch, M.C. (1997). SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18, 2714-2723.
16. Henry, K.R., D'Hondt, K., Chang, J., Newpher, T., Huang, K., Hudson, R.T., Riezman, H., and Lemmon, S.K. (2002). Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast. Mol. Biol. Cell 13, 2607-2625.
17. Huxley, C., Green, E.D., and Dunham, I. (1990). Rapid assessment of S. cerevisiae mating type by PCR. Trends Genet. 6, 236.
18. Imamura, H., Tanaka, K., Hihara, T., Umikawa, M., Kamei, T., Takahashi, K., Sasaki, T., and Takai, Y. (1997). Bni1p and Brtr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO J. 16, 2745-2755.
19. Kilmartin, J.V., and Adams, A.E. (1984). Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J. Cell Biol. 98, 922-933.
20. Kohno, H., et al. (1996). Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J. 15, 6060-6068.
21. Krebs, E.G. (1985). The phosphorylation of proteins: a major mechanism for biological regulation. Fourteenth Sir Frederick Gowland Hopkins memorial lecture. Biochem. Soc. Trans. 13, 813-820.
22. Lew, D.J., and Reed, S.I. (1993). Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins. J. Cell Biol. 120, 1305-1320.
23. Madhusudan, Trafny, E.A., Xuong, N.H., Adams, J.A., Ten Eyck, L.F., Taylor, S.S., and Sowadski, J.M. (1994). cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer. Protein Sci. 3, 176-187.
24. Nelson, K.K., and Lemmon, S.K. (1993). Suppressors of clathrin deficiency: overexpression of ubiquitin rescues lethal strains of clathrin-deficient Saccharomyces cerevisiae. Mol. Cell Biol. 13, 521-532.
25. Nelson, K.K., Holmer, M., and Lemmon, S.K. (1996). SCD5, a suppressor of clathrin deficiency, encodes a novel protein with a late secretory function in yeast. Mol. Biol. Cell 7, 245-260,
26. Pruyne, D., and Bretscher, A. (2000). Polarization of cell growth in yeast. J. Cell Sci. 113, 571-585.
27. Ricotta, D., Conner, S.D., Schmid, S.L., von Figura, K., and Honing, S. (2002). Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals. J. Cell Biol. 156, 791-795.
28. Rose, M.D., Winston, F., and Hieter, P. (1990). Methods in Yeast Genetics: A Laboratory Course Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
29. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
30. Smythe, E., and Ayscough, K.R. (2003). The Ark1/Prk1 family of protein kinases. EMBO Rep. 4, 246-251.
31. Tang, H.Y., and Cai, M. (1996). The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae. Mol. Cell Biol. 16, 4897-4914.
32. Tang, H.Y., Munn, A., and Cai, M. (1997). EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae. Mol. Cell Biol. 17, 4294-4304.
33. Tang, H.Y., Xu, J., and Cai, M. (2000). Pan1p, End3p, and S1a1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis. Mol. Cell Biol. 20, 12-25.
34. Vulliet, P.R., Hall, F.L., Mitchell, J.P., and Hardie, D.G. (1989). Identification of a novel proline-directed serine/threonine protein kinase in rat pheochromocytoma. J. Biol. Chem. 264, 16292-16298.
35. Watson, H.A., Cope, M.J., Groen, A.C., Drubin, D.G., and Wendland, B. (2001). In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation. Mol. Biol. Cell 12, 3668-3679.
36. Wendland, B., McCaffery, J.M., Xiao, Q., and Emr, S.D. (1996). A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15. J. Cell Biol. 135, 1485-1500.
37. Wendland, B., and Emr, S.D. (1998). Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis. J. Cell Biol, 141, 71-84.
38. Wendland, B., Steece, K.E., and Emr, S.D. (1999). Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 28, 4383-4393.
39. Winter, D., Lechler, T., and Li, R. (1999). Activation of the yeast Arp2/3 complex by Bee1p, a WASP-family protein. Curr. Biol. 9, 501-504.
40. Zeng, G., and Cai, M. (1999). Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p. J. Cell Biol. 144, 71-82.
41. Zeng, G., Yu, X., and Cai, M. (2001). Regulation of yeast actin cytoskeletonregulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p. Mol. Biol. Cell 12, 3759-3772.