Blockade of tetrahydrobiopterin synthesis protects neurons after transient forebrain ischemia in rat: A novel role for the cofactor

Journal of Neuroscience

Volumn 19, Issue 3, 1999, Pages 878-889

  Sunghee, Cho ^a   Volpe, Bruce T ^a   Youngmee, Bae ^a   Hwang, Onyou ^b   Choi, Hyun J ^b   Judit, Gal ^a   Park, Larry C H ^a   Chung K, Chu ^c   Jinfa, Du ^c   Tong H, Joh ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b University of Ulsan College of Medicine   (South Korea)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

CA1 hippocampus; N acetyl 3 O methyldopamine; Neuroprotection; Selective neuronal injury; Tetrahydrobiopterin (BH4); Transient forebrain ischemia

Indexed keywords

ARGININE; BIOPTERIN; FREE RADICAL; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CATALYSIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; HIPPOCAMPUS; HISTOCHEMISTRY; NERVE CELL DEGENERATION; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SYNTHESIS;

EID: 0345059268     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-03-00878.1999     Document Type: Article

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