Insulin-like growth factor-1 (IGF-1)-induced inhibition of growth hormone secretion is associated with sleep suppression

Brain Research

Volumn 818, Issue 2, 1999, Pages 267-274

  Obal Jr F ^a,b   Kapas L ^c   Gardi, J ^b   Taishi, P ^b   Bodosi, B ^a   Krueger, J M ^b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b Pharmacology   (United States)

^c FORDHAM UNIVERSITY   (United States)

Author keywords

EEG; GHRH; Growth hormone; IGF 1; Rabbits; Rats; Sleep; Somatostatin

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; SOMATOMEDIN C; SOMATOSTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE RELEASE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NEGATIVE FEEDBACK; NONHUMAN; NONREM SLEEP; PRIORITY JOURNAL; RABBIT; RAT; REM SLEEP; SLEEP; SLEEP DEPRIVATION; SLEEP WAKING CYCLE;

ANALYSIS OF VARIANCE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ELECTROENCEPHALOGRAPHY; FEEDBACK; HUMAN GROWTH HORMONE; INJECTIONS, INTRAVENTRICULAR; INSULIN-LIKE GROWTH FACTOR I; MALE; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SECRETORY RATE; SLEEP;

EID: 0344780706     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01286-4     Document Type: Article

References (49)

1. Abe H., Molitch M.E., Van Wyk J.J., Underwood J.J. Human growth hormone and somatomedine C suppress the spontaneous release of growth hormone in unanesthetized rats. Endocrinology. 113:1983;1319-1324.
2. Aguila M.C., Boggaram V., McCann S.M. Insulin-like growth factor I modulates hypothalamic somatostatin through a growth hormone releasing factor increased somatostatin release and messenger ribonucleic acid levels. Brain Res. 625:1993;213-218.
3. Åström C., Jochumsen P.L. Decrease in delta sleep in growth hormone deficiency assessed by a new power spectrum analysis. Sleep. 12:1989;508-515.
4. Åström C., Trojaborg W. Effect of growth hormone on human sleep energy. Clin. Endocrinol. 36:1992;241-245.
5. Becker K., Stegenga S., Conway S. Role of insulin-like growth factor I in regulating growth hormone release and feedback in the male rat. Neuroendocrinology. 61:1995;573-583.
6. Beranek L., Obál F. Jr., Taishi P., Bodosi B., Laczi F., Krueger J.M. Changes in rat sleep after single and repeated injections of the long-acting somatostatin analog octreotide. Am. J. Physiol. 273:1996;R1484-R1491.
7. Berelowitz M., Szabo M., Frohman L.A., Firestone S., Chu L. Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary. Science. 212:1981;1279-1281.
8. Bermann M., Jaffe C.A., Tsai W., DeMott-Friberg R., Barkan A.L. Negative feedback regulation of pulsatile growth hormone secretion by insulin-like growth factor I. J. Clin. Invest. 94:1994;138-145.
9. Brazeau P., Guillemin R., Ling N., Van Wyk J., Humbel R. Inhibition par les somatomédines de la sécrétion de l'hormone de croissance stimulée par le facteur hypothalamique somatocrinine (GRF) ou le peptide de synthèse hpGRF. C.R. Acad. Sci. Paris. 295:1982;651-654.
10. Bredow S., Taishi P., Obál F. Jr., Guha-Thakurta N., Krueger J.M. Hypothalamic growth hormone-releasing hormone mRNA varies across the day in rats. NeuroReport. 7:1996;2501-2505.
11. Danguir J., Nicolaidis S. Chronic intracerebroventricular infusion of insulin causes selective increase of slow wave sleep in rats. Brain Res. 306:1984;97-103.
12. Drucker-Colin R.R., Spanis C.W., Hunyadi J., Sassin J.F., McGaugh J.L. Growth hormone effects on sleep and wakefulness in the rat. Neuroendocrinology. 18:1975;1-8.
13. Ehlers C., Reed T.K., Henriksen S.J. Effects of corticotropin-releasing factor and growth hormone-releasing factor on sleep and activity in rats. Neuroendocrinology. 42:1986;467-474.
14. Frieboes R.-M., Murck H., Schier T., Holsboer F., Steiger A. Somatostatin impairs sleep in elderly human subjects. Neuropsychopharmacology. 16:1997;339-345.
15. Gardi J., Obál F. Jr., Zhang J., Fang J., Krueger J.M. Diurnal and sleep deprivation-induced changes in the GHRH contents of the rat hypothalamus (Abstract). J. Sleep Res. 7:1998;S2-S97.
16. Ghigo M.C., Torsello A., Grilli R., Luoni M., Guidi M., Cella S.G., Locatelli V., Müller E.E. Effects of GH and IGF-I administration on GHRH and somatostatin mRNA levels: I. A study on ad libitum fed and starved adult male rats. J. Endocrinol. Invest. 20:1997;144-150.
17. Gil Ad I., Weizman A., Silbergeld A., Dickerman Z., Kaplan B., Laron Z., Koch Y. Differential effect of insulin-like growth factor-I and growth hormone on hypothalamic regulation of growth hormone secretion in the rat. J. Endocrinol. Invest. 19:1996;542-547.
18. Harel Z., Tannenbaum S. Synergistic interaction between insulin-like growth factor-I and -II in central regulation of pulsatile growth hormone secretion. Endocrinology. 131:1992;758-764.
19. Kerkhofs M., Van Cauter E., Van Onderbergen A., Caufriez A., Thorner M.O., Copinschi G. Sleep-promoting effect of growth hormone-releasing hormone in normal men. Am. J. Physiol. 264:1993;E594-E598.
20. Lacmansingh E., Rollo C.D. Evidence for a trade-off between growth and behavioural activity in giant 'Supermice' genetically engineered with extra growth hormone genes. Can. J. Zool. 72:1994;2158-2168.
21. Marshall L., Molle M., Boschen G., Steiger A., Fehm H.L., Born J. Greater efficiacy of episodic than continuous growth hormone-releasing hormone (GHRH) administration in promoting slow-wave sleep (SWS). J. Clin. Endocrinol. Metab. 81:1996;1009-1013.
22. Mendelson W.B., Slater S., Gold P., Gillin J.C. The effect of growth hormone administration on human sleep: a dose-response study. Biol. Psychiatry. 15:1980;613-618.
23. Mitsugi N., Kimura F. Simultaneous determination of blood levels of corticosterone and growth hormone in the male rat: relation to sleep-wakefulness cycle. Neuroendocrinology. 41:1985;125-130.
24. Nistico G., DeSarro G.B., Bagetta G., Müller E.E. Behavioural and electrocortical spectrum power effects of growth hormone releasing factor in rats. Neuropharmacology. 26:1987;75-78.
25. Obál F. Jr., Alföldi P., Cady A.B., Johannsen L., Sáry G., Krueger J.M. Growth hormone-releasing factor enhances sleep in rats and rabbits. Am. J. Physiol. 255:1988;R310-R316.
26. Obál F. Jr., Bodosi B., Szilágyi A., Kacsóh B., Krueger J.M. Antiserum to growth hormone suppresses sleep in the rat. Neuroendocrinology. 66:1997;9-16.
27. Obál F. Jr., Floyd R., Kapás L., Bodosi B., Krueger J.M. Effects of systemic GHRH on sleep in intact and hypophysectiomized rats. Am. J. Physiol. 270:1996;E230-E237.
28. Obál F. Jr., Kapás L., Bodosi B., Krueger J.M. Changes in sleep in response to intracerebral injection of insulin-like growth factor-1 (IGF-1) in the rat. Sleep Res. Online. 1:1998;87-91.
29. Obál F. Jr., Payne L., Kapás L., Opp M., Krueger J.M. Inhibition of growth hormone-releasing factor suppresses both sleep and growth hormone secretion in the rat. Brain Res. 557:1991;149-153.
30. Obál F. Jr., Payne L., Opp M., Alföldi P., Kapás L., Krueger J.M. Growth hormone-releasing hormone antibodies suppress sleep and prevent enhancement of sleep after sleep deprivation. Am. J. Physiol. 263:1992;R1078-R1085.
31. Oscarsson J., Johannsson G., Johansson J.-O., Lundberg P.-A., Lindstedt G., Bengtsson B.-A. Diurnal variation in serum insulin-like growth factor (IGF)-I and IGF binding protein-3 concentrations during daily subcutaneous injections of recombinant human growth hormone in GH-deficient adults. Clin. Endocrinology. 46:1997;63-68.
32. Prinz P.N., Moe K.E., Dulberg E.M., Larsen L.H., Vitiello M.V., Toivola B., Merriam G.R. Higher plasma IGF-1 levels are associated with increased delta sleep in healthy older men. J. Gerontol. 50A:1995;M222-226.
33. Sara V.R., Clayton K., Cooke P., Craven C.J., Garcia-Aragon J., Harmon B., Harvey M., Haase H., Plenderleith M., Richardson N., Sherrard R., Stahlbom P.-A., Walker G., Walsh T.P. The brain IGF system: implications for Down syndrome. Dev. Brain Dysfunct. 9:1996;85-92.
34. Sato M., Frohman L.A. Differential effects of central and peripheral administration of growth hormone (GH) and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats. Endocrinology. 133:1993;793-799.
35. Shibasaki T., Yamauchi N., Hotta M., Masuda A., Imaki T., Demura H., Ling N., Shizume K. In vitro release of growth hormone-releasing factor from rat hypothalamus: effect of insulin-like growth factor-I. Regul. Pept. 15:1986;47-53.
36. Spencer G.S., Bass J.J., Hodgkinson S.C., Edgley W.H., Moore L.G. Effect of intracerebroventricular injection of IGF-I on circulating growth hormone concentrations in the sheep. Domest. Anim. Endocrinol. 8:1991;155-160.
37. Spencer G.S.G., Macdonald A.A., Buttle H.L., Moore L.G., Carlyle S.S. Intracerebral administration of insulin-like growth factor 1 decreases circulating hormone levels in the fetal pig. Acta Endocrinologica (Copenhagen). 124:1991;563-568.
38. Steiger A., Guldner J., Hemmeter U., Rothe B., Wiedemann K., Holsboer F. Effects of growth hormone-releasing hormone and somatostatin on sleep EEG and nocturnal hormone secretion in male controls. Neuroendocrinology. 56:1992;566-573.
39. Stern W.C., Jalowiec J.E., Shabshelowitz H., Morgane P. Effects of growth hormone on sleep-waking patterns in cats. Horm. Behav. 6:1975;189-196.
40. Stewart C.E.H., Rotwein P. Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors. Physiol. Rev. 76:1996;1005-1026.
41. Tannenbaum G.S., Guyda H.J., Posner B.I. Insulin-like growth factors: a role in growth hormone negative feedback and body weight regulation via brain. Science. 220:1983;77-79.
42. Tannenbaum G.S., Martin J.B. Evidence for an endogenous rhythm governing growth hormone secretion in the rat. Endocrinology. 98:1976;562-570.
43. Toppila J., Alanko L., Asikainen M., Tobler I., Stenberg D., Porkka-Heiskanen T. Sleep deprivation increases somatostatin and growth hormone-releasing hormone messenger RNA in the rat hypothalamus. J. Sleep Res. 6:1997;171-178.
44. Uchiyama T., Kaji H., Abe H., Chihara K. Negative regulation of hypothalamic growth hormone-releasing factor messenger ribonucleic acid by growth hormone and insulin-like growth factor I. Neuroendocrinology. 59:1994;441-450.
45. Van Cauter E., Plat L. Physiology of growth hormone secretion during sleep. J. Pediatr. 128:1996;S32-S37.
46. Willoughby J.O., Martin J.B. The suprachiasmatic nucleus synchronizes growth hormone secretory rhythms with the light-dark cycle. Brain Res. 151:1978;413-417.
47. Wood T.L., Berelowitz M., Gelato M.C., Roberts C.T. Jr., LeRoith D., Millard W.J., McKelvy J.F. Hormonal regulation of rat hypothalamic neuropeptide mRNAs: effect of hypophysectomy and hormone replacement on growth hormone-releasing factor, somatostatin and the insulin-like growth factors. Neuroendocrinology. 53:1991;298-305.
48. Zhang J., Chen Z., Taishi P., Obál F. Jr., Krueger J.M. Sleep deprivation increases rat hypothalamic growth hormone-releasing mRNA. Am. J. Physiol. 44:1998;R1755-1761.
49. Zhang J., Obál F. Jr., Fang J., Krueger J.M. Non-rapid eye movement sleep (NREMS) is enhanced by microinjection of growth hormone-releasing hormone (GHRH) into the preoptic area in rats (Abstract). Soc. Neurosci. Abstr. 23:1997;1067.