Greater efficacy of episodic than continuous growth hormone-releasing hormone (GHRH) administration in promoting slow-wave sleep (SWS)

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 3, 1996, Pages 1009-1013

  Marshall, Lisa ^a,c   Mölle, Matthias ^a   Böschen, Gerhard ^a   Steiger, Axel ^b   Fehm, Horst L ^a   Born, Jan ^a,c  

^a UNIVERSITY OF LÜBECK   (Germany)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^c UNIVERSITY OF BAMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RELEASING FACTOR; HYDROCORTISONE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; GROWTH HORMONE BLOOD LEVEL; HORMONAL REGULATION; HORMONAL THERAPY; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; MALE; NORMAL HUMAN; PRIORITY JOURNAL; REM SLEEP; SLEEP INDUCTION; SLOW WAVE SLEEP; WAKEFULNESS;

ADULT; GROWTH HORMONE; GROWTH HORMONE-RELEASING HORMONE; HUMANS; HYDROCORTISONE; MALE; OSMOLAR CONCENTRATION; PULSATILE FLOW; SLEEP; SLEEP STAGES;

EID: 0029989311     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.3.1009     Document Type: Article

References (29)

1. Ehlers CL, Reed TK, Henriksen SJ. 1986 Effects of corticotropin-releasing factor and growth hormone-releasing factor on sleep and activity in rats. Neuroendocrinology. 42:467-474.
2. Nistico G, De Sarro GB, Bagetta G, Müller EE. 1987 Behavioral and electrocortical spectrum power effects of growth hormone-releasing factors in rats. Neuropharmacology. 26:75-78.
3. Obal F Jr, Alföldi P, Cady AB, Johannsen L, Sary G, Krueger JM. 1988 Growth hormone-releasing factor enhances sleep in rats and rabbits. Am J Physiol. 255:R310-316.
4. Kupfer DJ, Jarrett DB, Ehlers CL. 1991 The effect of GRF on the EEG sleep of normal males. Sleep. 14:87-88.
5. Obál F Jr, Payne L, Kapás L, Opp M, Krueger JM. 1991 Inhibition of growth hormone-releasing factor suppresses both sleep and growth hormone secretion in the rat. Brain Res. 557:149-153.
6. Kapás L, Obál F Jr, Krueger JM. 1993 Humoral regulation of sleep. Int Rev Neurobiol. 35:131-159.
7. Steiger A. 1995 Schlafendokrinologie. Nervenarzt. 66:15-27.
8. Born J, Muth S, Fehm HL. 1988 The significance of sleep onset and slow wave sleep for nocturnal release of growth hormone (GH) and cortisol. Psychoneuroendocrinol. 13:233-243.
9. Holl RW, Hartman ML, Veldhuis JD, Taylor WM, Thorner MO. 1991 Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages. J Clin Endocrinol Metab; 72:854-861.
10. Garry P, Roussel B, Cohen R, et al. 1985 Diurnal administration of human growth hormone-releasing factor does not modify sleep and sleep-related growth hormone secretion in normal young men. Acta Endocrinol (Copenh). 110:158-163.
11. Sassolas G, Garry J, Cohen R, et al. 1986 Nocturnal continuous infusion of growth hormone (GH)-releasing hormone results in a dose-dependent accentuation of episodic GH secretion in normal men. J Clin Endocrinol Metab. 63:1016-1022.
12. Kern W, Halder R, Al-Reda S, Späth-Schwalbe E, Fehm HL, Born J. 1993 Systemic growth hormone does not affect human sleep. J Clin Endocrinol Metab. 63:1428-1432.
13. Kerkhofs M, Van Cauter E, Van Onderbergen A, Gaufriez A, Thorner MO, Copinschi G. 1993 Sleep-promoting effects of growth hormone-releasing hormone in normal men. Am J Physiol. 264:E594-98.
14. Steiger A, Guldner J, Hemmeter U, Rothe B, Wiedemann K, Holsboer F. 1992 Effects of growth hormone-releasing and somatostatin on sleep EEG and nocturnal hormone secretion in male controls. Neuroendocrinology. 56:566-573.
15. Borges JLC, Uskavitch DR, Kaiser DL, Cronin MJ, Evans WS, Thorner MO. 1983 Human pancreatic growth hormone-releasing factor-40 (hpGRF-40) allows stimulation of GH release by TRH. Endocrinology. 113:1519-1521.
16. Badger TM, Loughlin JS, Naddaff PG. 1983 The luteinizing hormone-releasing hormone (LHRH)-desensitized rat pituitary: luteinizing hormone responsiveness to LHRH in vitro. Endocrinology. 112:793-799.
17. Tannenbaum GS, Ling N. 1984 The interrelationship of growth hormone (GH)-releasing factor and somatostatin in generation of the ultradian rhythm of GH secretion. Endocrinology. 115:1952-1957.
18. Plotsky PM, Vale W. 1986 Patterns of growth hormone-releasing factor and somatostatin secretion into the hypophyseal-portal circulation of the rat. Science. 230:461-465.
19. Van Cauter E, Caufriez A, Kerkhofs M, Onderbergen AE, Thorner MO, Copinschi G. 1992 Sleep, awakenings, and insulin-like growth factor-I modulate the growth (GH) secretory response to GH-releasing hormone. J Clin Endocrinol Metab. 74:1451-1459.
20. Rechtschaffen A, Kales A. 1968 A manual of standardized terminology, techniques, and scoring system for sleep stages of human subjects. NIH Publ 204, US Government Printing Office, Washington, DC.
21. Gelato MC, Rittmaster RS, Pescovitz OH, et al. 1985 Growth hormone response to continuous infusions of growth hormone-releasing hormone. J Clin Endocrinol Metab. 61:223-228.
22. Schier T, Holsboer F, Guldner J, Colla-Müller M, Steiger A. 1994 Changes of sleep-endocrine activity after growth hormone-releasing hormone (GHRH) depend on time of application. Naunyn-Schmiedebergs Arch Pharmacol. 349: R146.
23. Belchetz PE, Plant TM, Nakai Y, Keogh EJ, Knobil E. 1978 Hypophysial responses to continuous and intermittent delivery of hypothalamic gonadotropin-releasing hormone. Science. 202:631-633.
24. Webb CB, Vance ML, Thorner MO, et al. 1984 Plasma growth hormone responses to constant infusions of human pancreatic growth hormone releasing factor. J Clin Invest. 74:96-103.
25. Frohman LA, Downs TR, Williams TC, Heimer EP, Pan YCE, Felix AM. 1986 Rapid enzymatic degradation of growth hormone-releasing hormone by plasma in vitro and in vivo to a biologically inactive product cleaved at the NH2 terminus. J Clin Invest. 78:906-913.
26. Edwardson JA, Gilbert D. 1976 Application of an in vitro perifusion technique to studies of luteinizing hormone released by rat anterior hemi-pituitaries: self-potentiation by luteinizing hormone releasing hormone. J Endocrinol. 68:197-207.
27. Lumpkin ML, McDonald JK. 1989 Blockade of growth hormone-releasing factor (GRF) activity in the pituitary and hypothalamus of the conscious rat with a peptide GRF antagonist. Endocrinology. 124:1522-1531.
28. Sawchenko PE, Swanson LW, River J, Vale WW. 1985 The distribution of growth hormone-releasing factor (GRF) immunoreactivity in the central nervous system of the rat: an immunohistochemical study using antisera directed against rat hypothalamic GRF. J Comp Neurol. 237:100-115.
29. Krueger JM, Obál Jr F. 1993 Growth hormone-releasing hormone, and interleukin-1 in sleep regulation. FASEB J. 7:645-652.