Presynaptic adenosine A2A receptors enhance GABAergic synaptic transmission via a cyclic AMP dependent mechanism in the rat globus pallidus

British Journal of Pharmacology

Volumn 136, Issue 2, 2002, Pages 296-302

  Shindou, Tomomi ^a   Nonaka, Hiromi ^a   Richardson, Peter J ^b   Mori, Akihisa ^a   Kase, Hiroshi ^a   Ichimura, Michio ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Basal ganglia; Brain slices; CGS21680; Globus pallidus; KF17837

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 8 (3,4 DIMETHOXYSTYRYL) 7 METHYL 1,3 DIPROPYLXANTHINE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENYLATE CYCLASE ACTIVATOR; ADENYLATE CYCLASE INHIBITOR; CALCIUM CHANNEL BLOCKING AGENT; CYCLIC AMP; ENZYME INHIBITOR; FORSKOLIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; ADENOSINE RECEPTOR; PRESYNAPTIC RECEPTOR;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; GABAERGIC SYSTEM; GLOBUS PALLIDUS; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; ACTION POTENTIAL; ANIMAL; DRUG EFFECT; DRUG POTENTIATION; IN VITRO STUDY; MALE; METABOLISM; PHYSIOLOGY; SECRETION; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANIMALS; CYCLIC AMP; GAMMA-AMINOBUTYRIC ACID; GLOBUS PALLIDUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A2A; RECEPTORS, PRESYNAPTIC; RECEPTORS, PURINERGIC P1; SYNAPTIC TRANSMISSION;

EID: 0036015186     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704702     Document Type: Article

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