메뉴 건너뛰기




Volumn 134, Issue 2-3, 1999, Pages 197-207

Cytokines, growth factors, and oxidative stress in HepG2 cells treated with ethanol, acetaldehyde, and LPS

Author keywords

Acetaldehyde; Cytokines; Ethanol; Growth factors; HepG2 cells; LPS; Oxidative stress

Indexed keywords

ACETALDEHYDE; ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; CYTOKINE; FREE RADICAL; GLUTATHIONE; GLUTATHIONE REDUCTASE; GROWTH FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; MALONALDEHYDE; NEUTRAL RED; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 0344603603     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(99)00044-X     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 0018718742 scopus 로고
    • Controlled synthesis of HBsAg in a differentiated human liver carcinoma derived cell line
    • Aden D.P., Fogel A., Plotkin S., Damjanov I., Knowles B. Controlled synthesis of HBsAg in a differentiated human liver carcinoma derived cell line. Nature. 282:1979;615-616.
    • (1979) Nature , vol.282 , pp. 615-616
    • Aden, D.P.1    Fogel, A.2    Plotkin, S.3    Damjanov, I.4    Knowles, B.5
  • 2
    • 0019743482 scopus 로고
    • Effects of ethanol on hepatic protein secretion and microtubules: Possible mediation by acetaldehyde
    • M. Galanter. New York: Grune and Stratton
    • Baraona E., Matsuda Y., Pikkarainen P., Finkelman F., Lieber C.S. Effects of ethanol on hepatic protein secretion and microtubules: possible mediation by acetaldehyde. Galanter M. Currents in Alcoholism, vol. 8. 1981;421-434 Grune and Stratton, New York.
    • (1981) Currents in Alcoholism, Vol. 8 , pp. 421-434
    • Baraona, E.1    Matsuda, Y.2    Pikkarainen, P.3    Finkelman, F.4    Lieber, C.S.5
  • 3
    • 0029026662 scopus 로고
    • Transforming growth factor-β: A key-role in liver fibrogenesis
    • Bedossa P., Paradis V. Transforming growth factor-β: a key-role in liver fibrogenesis. J. Hepatol. 22:1995;37-42.
    • (1995) J. Hepatol. , vol.22 , pp. 37-42
    • Bedossa, P.1    Paradis, V.2
  • 5
    • 0029159792 scopus 로고
    • Cell-specific expression of TGF-β1 in rat liver - Evidence for autocrine regulation of hepatocytes proliferation
    • Bissell D.M., Wang S.S., Jarnagin W.R., Roll F.J. Cell-specific expression of TGF-β1 in rat liver - evidence for autocrine regulation of hepatocytes proliferation. J. Clin. Invest. 96:1995;447-455.
    • (1995) J. Clin. Invest. , vol.96 , pp. 447-455
    • Bissell, D.M.1    Wang, S.S.2    Jarnagin, W.R.3    Roll, F.J.4
  • 6
    • 0027467834 scopus 로고
    • Hidden endotoxin in plasma of patients with alcoholic liver disease
    • Bode C., Fukin H., Bode J.C. Hidden endotoxin in plasma of patients with alcoholic liver disease. Eur. J. Gastroenterol. Hepatol. 5:1993;257-262.
    • (1993) Eur. J. Gastroenterol. Hepatol. , vol.5 , pp. 257-262
    • Bode, C.1    Fukin, H.2    Bode, J.C.3
  • 7
    • 0028109801 scopus 로고
    • Mechanisms of disease: Transforming growth factor beta in tissue fibrosis
    • Border W.A., Noble N.A. Mechanisms of disease: transforming growth factor beta in tissue fibrosis. N. Engl. J. Med. 331:1994;1286-1292.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 8
    • 0022651314 scopus 로고
    • Cytotoxicity of metals, metal-metal and metal-quelator combinations in vitro
    • Borenfreund E., Puerner J.A. Cytotoxicity of metals, metal-metal and metal-quelator combinations in vitro. Toxicology. 39:1985;121-134.
    • (1985) Toxicology , vol.39 , pp. 121-134
    • Borenfreund, E.1    Puerner, J.A.2
  • 9
    • 0026786405 scopus 로고
    • Standarization of mRNA titration using a polymerase chain reaction method involving co-amplification with multispecific internal control
    • Bouaboula M., Legoux P., Pessegue B. et al. Standarization of mRNA titration using a polymerase chain reaction method involving co-amplification with multispecific internal control. J. Biol. Chem. 267:1994;21830-21836.
    • (1994) J. Biol. Chem. , vol.267 , pp. 21830-21836
    • Bouaboula, M.1    Legoux, P.2    Pessegue, B.3
  • 10
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege J.A., Aust S.D. Microsomal lipid peroxidation. Methods Enzymol. 52:1978;302-310.
    • (1978) Methods Enzymol. , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 11
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 13
    • 0032137199 scopus 로고    scopus 로고
    • Toxic metals stimulate inflammatory cytokines in hepatocytes through oxidative stress mechanisms
    • Dong W., Simeonova P.P., Gallucci R. et al. Toxic metals stimulate inflammatory cytokines in hepatocytes through oxidative stress mechanisms. Tox. Appl. Pharmacol. 151:1998;359-366.
    • (1998) Tox. Appl. Pharmacol. , vol.151 , pp. 359-366
    • Dong, W.1    Simeonova, P.P.2    Gallucci, R.3
  • 14
    • 0031869568 scopus 로고    scopus 로고
    • Cytokine expression in hepatocytes: Role of oxidant stress
    • Dong W., Simeonova P.P., Gallucci R. et al. Cytokine expression in hepatocytes: role of oxidant stress. J. Interf. Cytokine Res. 18:1998;629-638.
    • (1998) J. Interf. Cytokine Res. , vol.18 , pp. 629-638
    • Dong, W.1    Simeonova, P.P.2    Gallucci, R.3
  • 15
    • 0025278936 scopus 로고
    • Plasma tumor necrosis factor alpha predicts long-term survival in severe alcoholic hepatitis
    • Felver M.E., Mezey E., McGire M., Nathan C. Plasma tumor necrosis factor alpha predicts long-term survival in severe alcoholic hepatitis. Alcohol Clin. Exp. Res. 114:1990;255-259.
    • (1990) Alcohol Clin. Exp. Res. , vol.114 , pp. 255-259
    • Felver, M.E.1    Mezey, E.2    McGire, M.3    Nathan, C.4
  • 17
    • 0029887145 scopus 로고    scopus 로고
    • Transforming growth factor β expression in isolated and cultured rat hepatocyte
    • Gao C., Gressner G., Zoremba M., Gressner A.M. Transforming growth factor β expression in isolated and cultured rat hepatocyte. J. Cell Physiol. 167:1996;394-405.
    • (1996) J. Cell Physiol. , vol.167 , pp. 394-405
    • Gao, C.1    Gressner, G.2    Zoremba, M.3    Gressner, A.M.4
  • 18
    • 0028868238 scopus 로고
    • S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes
    • García-Ruiz C., Colell A., Morales A., Kaplowitz N., Fernández-Checa J.C. S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes. Hepatology. 21:1995;207-214.
    • (1995) Hepatology , vol.21 , pp. 207-214
    • García-Ruiz, C.1    Colell, A.2    Morales, A.3    Kaplowitz, N.4    Fernández-Checa, J.C.5
  • 19
    • 0033534717 scopus 로고    scopus 로고
    • Interleukin 1 induced nuclear factor-kappaB-IkappaBalpha autoregulatory feedback loop in hepatocytes. A role for protein kinase calpha in post-transcriptional regulatory of ikappabalpha resynthesis
    • Han Y., Meng T., Murray N.R., Fields A.P., Brasier A.R. Interleukin 1 induced nuclear factor-kappaB-IkappaBalpha autoregulatory feedback loop in hepatocytes. A role for protein kinase calpha in post-transcriptional regulatory of ikappabalpha resynthesis. J. Biol. Chem. 274:1999;939-947.
    • (1999) J. Biol. Chem. , vol.274 , pp. 939-947
    • Han, Y.1    Meng, T.2    Murray, N.R.3    Fields, A.P.4    Brasier, A.R.5
  • 20
    • 0026655214 scopus 로고
    • Increased plasma interleukin-6 concentrations in alcoholic hepatitis
    • Hill D.B., Marsano L., Cohen D., McClain C.J. Increased plasma interleukin-6 concentrations in alcoholic hepatitis. J. Lab. Clin. Med. 119:1992;547-552.
    • (1992) J. Lab. Clin. Med. , vol.119 , pp. 547-552
    • Hill, D.B.1    Marsano, L.2    Cohen, D.3    McClain, C.J.4
  • 22
    • 0027978109 scopus 로고
    • Regulation of mannose 6-phosphate/insulin-like factor-II receptors and transforming growth factor beta during tumor promotion with phenobarbital
    • Jirtle R.L., Hankins G.R., Reisenbichler H., Boyer J.J. Regulation of mannose 6-phosphate/insulin-like factor-II receptors and transforming growth factor beta during tumor promotion with phenobarbital. Carcinogenesis. 15:1994;1473-1478.
    • (1994) Carcinogenesis , vol.15 , pp. 1473-1478
    • Jirtle, R.L.1    Hankins, G.R.2    Reisenbichler, H.3    Boyer, J.J.4
  • 23
    • 0029121402 scopus 로고
    • Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease
    • Kanimura S., Tsukamoto H. Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease. Hepatology. 21:1995;1304-1309.
    • (1995) Hepatology , vol.21 , pp. 1304-1309
    • Kanimura, S.1    Tsukamoto, H.2
  • 25
    • 0032466411 scopus 로고    scopus 로고
    • Suppresive effect of ethanol on the expression of hepatic asialoglycoprotein receptors augmented by interleukin 1 beta, interleukin 6 and tumor necrosis factor-alpha
    • Kato J., Mogi Y., Kohgo Y., Takimoto R., Kobune M., Hisai H., Nakamura T., Takada K., Niitsu Y. Suppresive effect of ethanol on the expression of hepatic asialoglycoprotein receptors augmented by interleukin 1 beta, interleukin 6 and tumor necrosis factor-alpha. J. Gastroenterol. 36:1998;855-859.
    • (1998) J. Gastroenterol. , vol.36 , pp. 855-859
    • Kato, J.1    Mogi, Y.2    Kohgo, Y.3    Takimoto, R.4    Kobune, M.5    Hisai, H.6    Nakamura, T.7    Takada, K.8    Niitsu, Y.9
  • 26
    • 0026026639 scopus 로고
    • Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients
    • Khoruts A., Stanke L., McClain C.F., Logan G., Allen J.I. Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients. Hepatology. 13:1991;267-276.
    • (1991) Hepatology , vol.13 , pp. 267-276
    • Khoruts, A.1    Stanke, L.2    McClain, C.F.3    Logan, G.4    Allen, J.I.5
  • 27
    • 0002982414 scopus 로고
    • Kupffer and sinusoidal endothelial cells
    • I.M. Arias, J.L. Boyer, N. Fausto, W.B. Jakoby, D.A. Schachter, & D.A. Shafritz. New York: Raven Press
    • Kuiper J., Brouwer A., Knnok D.L., van Berkel T.J.C. Kupffer and sinusoidal endothelial cells. Arias I.M., Boyer J.L., Fausto N., Jakoby W.B., Schachter D.A., Shafritz D.A. The Liver: Biology and Pathobiology. 4th ed:1994;791-818 Raven Press, New York.
    • (1994) The Liver: Biology and Pathobiology 4th Ed , pp. 791-818
    • Kuiper, J.1    Brouwer, A.2    Knnok, D.L.3    Van Berkel, T.J.C.4
  • 28
    • 0029123422 scopus 로고
    • Cellular signals in alcohol induced liver injury. A review
    • Lands W.E.M. Cellular signals in alcohol induced liver injury. A review. Alcohol. Clin. Exp. Res. 19:1995;928-938.
    • (1995) Alcohol. Clin. Exp. Res. , vol.19 , pp. 928-938
    • Lands, W.E.M.1
  • 29
    • 0026953017 scopus 로고
    • Simultaneous quantitation of cytokine mRNAs in interleukin-β stimulated U373 human astrocytoma cells by a polymerization chain reaction method involving co-amplification with an internal multispecific control
    • Legoux P., Minty C., Delpech B., Minty A.J., Shire D. Simultaneous quantitation of cytokine mRNAs in interleukin-β stimulated U373 human astrocytoma cells by a polymerization chain reaction method involving co-amplification with an internal multispecific control. Eur. Cytokine Netw. 3:1992;553-563.
    • (1992) Eur. Cytokine Netw. , vol.3 , pp. 553-563
    • Legoux, P.1    Minty, C.2    Delpech, B.3    Minty, A.J.4    Shire, D.5
  • 31
    • 0028014478 scopus 로고
    • Endotoxin-induced cytokine gene expression and excretion in the liver
    • Luster M.I., Germolec D.R., Yoshida I., Kayama F., Thompson M. Endotoxin-induced cytokine gene expression and excretion in the liver. Hepatology. 19:1994;480-488.
    • (1994) Hepatology , vol.19 , pp. 480-488
    • Luster, M.I.1    Germolec, D.R.2    Yoshida, I.3    Kayama, F.4    Thompson, M.5
  • 35
    • 0031802169 scopus 로고    scopus 로고
    • Role of cytokines in ethanol-induced cytotoxicity in vitro in HepG2 cells
    • Neuman M.G., Shear N.H., Bellentani S., Tiribelli C. Role of cytokines in ethanol-induced cytotoxicity in vitro in HepG2 cells. Gastroenterology. 115:1998;157-166.
    • (1998) Gastroenterology , vol.115 , pp. 157-166
    • Neuman, M.G.1    Shear, N.H.2    Bellentani, S.3    Tiribelli, C.4
  • 36
    • 85072189100 scopus 로고
    • Molecular mechanisms of toxic cell death: an overview
    • In: Tyson C.A., Frazier J.M. (Eds.), Academic Press, USA
    • Nicotera, P., Orrenius, S., 1994. Molecular mechanisms of toxic cell death: an overview. In: Tyson C.A., Frazier J.M. (Eds.), In Vitro Toxicity Indicators. Academic Press, USA, pp. 23-32.
    • (1994) In Vitro Toxicity Indicators , pp. 23-32
    • Nicotera, P.1    Orrenius, S.2
  • 37
    • 0030067146 scopus 로고    scopus 로고
    • The antiandrogen cyproterone acetate induces synthesis of TGF in the parenchymal cells of the liver accompanied by and enhanced sensitivity to undergo apoptosis and necrosis without inflammation
    • Oberhammer F., Nagy P., Tiefenbacher R., Fröschl G., Bouzahzah B., Thorgeirsson S.S., Carr B. The antiandrogen cyproterone acetate induces synthesis of TGF in the parenchymal cells of the liver accompanied by and enhanced sensitivity to undergo apoptosis and necrosis without inflammation. Hepatology. 23:1996;329-337.
    • (1996) Hepatology , vol.23 , pp. 329-337
    • Oberhammer, F.1    Nagy, P.2    Tiefenbacher, R.3    Fröschl, G.4    Bouzahzah, B.5    Thorgeirsson, S.S.6    Carr, B.7
  • 39
    • 0030918232 scopus 로고    scopus 로고
    • Comparative study of the damage produced by acute ethanol and acetaldehyde treatment in a human fetal hepatic cell line
    • Olivares I.P., Bucio L., Souza V., Cárabez A., Gutiérrez-Ruiz M.C. Comparative study of the damage produced by acute ethanol and acetaldehyde treatment in a human fetal hepatic cell line. Toxicology. 120:1997;133-144.
    • (1997) Toxicology , vol.120 , pp. 133-144
    • Olivares, I.P.1    Bucio, L.2    Souza, V.3    Cárabez, A.4    Gutiérrez-Ruiz, M.C.5
  • 41
    • 66349129125 scopus 로고
    • A colorimetric method for the determination of serum oxaloacetic and glutamic pyruvic transaminases
    • Reitman S., Frankel S. A colorimetric method for the determination of serum oxaloacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 28:1957;56-63.
    • (1957) Am. J. Clin. Pathol. , vol.28 , pp. 56-63
    • Reitman, S.1    Frankel, S.2
  • 42
    • 0028085132 scopus 로고
    • Bacterial endotoxin molecular relationships of structure to activity and function
    • Rietschel E.I., Kinkae I., Schode F.U. et al. Bacterial endotoxin molecular relationships of structure to activity and function. FASEB J. 8:1994;217-225.
    • (1994) FASEB J. , vol.8 , pp. 217-225
    • Rietschel, E.I.1    Kinkae, I.2    Schode, F.U.3
  • 43
    • 0030979376 scopus 로고    scopus 로고
    • Expression and release of the latent transforming growth factor β binding protein by hepatocytes from rat liver
    • Roth S., Schurekk J., Gressner A.M. Expression and release of the latent transforming growth factor β binding protein by hepatocytes from rat liver. Hepatology. 25:1997;1398-1405.
    • (1997) Hepatology , vol.25 , pp. 1398-1405
    • Roth, S.1    Schurekk, J.2    Gressner, A.M.3
  • 44
    • 0028927057 scopus 로고
    • Hepatocyte-derived interleukin-6 and tumor-necrosis factor α mediate the lipopolysaccharide-induced acute-phase response and nitric oxide release by cultured rat hepatocytes
    • Saad B., Frei K., Scholl F.A., Fontana A., Maier P. Hepatocyte-derived interleukin-6 and tumor-necrosis factor α mediate the lipopolysaccharide-induced acute-phase response and nitric oxide release by cultured rat hepatocytes. Eur. J. Biochem. 229:1995;349-355.
    • (1995) Eur. J. Biochem. , vol.229 , pp. 349-355
    • Saad, B.1    Frei, K.2    Scholl, F.A.3    Fontana, A.4    Maier, P.5
  • 45
    • 0027427964 scopus 로고
    • The mechanism for the activation of latent TGF-β During co-culture of endothelial cells and smooth muscle cells-cell type. Specific targeting of latent TGF-β1 to smooth muscle cells
    • Sato Y., Okada F., Abe M., Seguchi T., Kuwano M., Sato S., Furuya A. The mechanism for the activation of latent TGF-β during co-culture of endothelial cells and smooth muscle cells-cell type. Specific targeting of latent TGF-β1 to smooth muscle cells. J. Cell Biol. 123:1993;1249-1254.
    • (1993) J. Cell Biol. , vol.123 , pp. 1249-1254
    • Sato, Y.1    Okada, F.2    Abe, M.3    Seguchi, T.4    Kuwano, M.5    Sato, S.6    Furuya, A.7
  • 47
    • 0029984062 scopus 로고    scopus 로고
    • Antioxidant and redox regulation of gene transcription
    • Sen C.K., Packer L. Antioxidant and redox regulation of gene transcription. FASEB J. 10:1996;709-720.
    • (1996) FASEB J. , vol.10 , pp. 709-720
    • Sen, C.K.1    Packer, L.2
  • 48
    • 0014481378 scopus 로고
    • Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27:1969;502-522.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 49
    • 0027954759 scopus 로고
    • Structure-activity studies of human tumor necrosis factor
    • Van Ostade X., Tavernien J., Fiers W. Structure-activity studies of human tumor necrosis factor. Protein Eng. 7:1994;5-22.
    • (1994) Protein Eng. , vol.7 , pp. 5-22
    • Van Ostade, X.1    Tavernien, J.2    Fiers, W.3
  • 50
    • 0029997368 scopus 로고    scopus 로고
    • Hepatic silicosis, cirrhosis and liver tumors in mice and hamsters: Studies of transforming growth factor beta expression
    • Williams A.U., Knapton A.V. Hepatic silicosis, cirrhosis and liver tumors in mice and hamsters: studies of transforming growth factor beta expression. Hepatology. 23:1996;1268-1275.
    • (1996) Hepatology , vol.23 , pp. 1268-1275
    • Williams, A.U.1    Knapton, A.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.