Synthesis and Biological Evaluation of 4-Arylcoumarin Analogues of Combretastatins

Journal of Medicinal Chemistry

Volumn 46, Issue 25, 2003, Pages 5437-5444

  Bailly, Christian ^a   Bal, Christine ^a   Barbier, Pascale ^b   Combes, Sébastien ^b   Finet, Jean Pierre ^b   Hildebrand, Marie Paule ^a   Peyrot, Vincent ^b   Wattez, Nicole ^a  

^a Institut de Recherche sur le Cancer de Lille   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; COMBRETASTATIN; COMBRETASTATIN A4; COUMARIN DERIVATIVE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); GENISTEIN; HYDROXYL GROUP; PARA COUMARIN DERIVATIVE; PODOPHYLLOTOXIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CELL STRAIN; CELL STRAIN CEM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL LINE; MICROTUBULE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOPOLYMERS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 0344550356     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030903d     Document Type: Article

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