메뉴 건너뛰기




Volumn 10, Issue 3, 2003, Pages 328-336

Glass needle-mediated microinjection of macromolecules and transgenes into primary human mesenchymal stem cells

Author keywords

Gene delivery methods; Gene therapy; Mesenchymal stem cells; Microinjection

Indexed keywords

DEXTRAN; PLASMID DNA; PYA 721; UNCLASSIFIED DRUG;

EID: 0344511615     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1159/000070098     Document Type: Article
Times cited : (40)

References (56)
  • 1
    • 0028362018 scopus 로고
    • Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts
    • Alberts A, Montminy M, Shenolikar S, Feramisco J. Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. Mol Cell Biol 14:4398-4407;1994.
    • (1994) Mol Cell Biol , vol.14 , pp. 4398-4407
    • Alberts, A.1    Montminy, M.2    Shenolikar, S.3    Feramisco, J.4
  • 2
    • 0020436088 scopus 로고
    • Improved system for capillary microinjection into living cells
    • Ansorge W. Improved system for capillary microinjection into living cells. Exp Cell Res 140:31-37;1982.
    • (1982) Exp Cell Res , vol.140 , pp. 31-37
    • Ansorge, W.1
  • 3
    • 0023715174 scopus 로고
    • Performance of an automated system for capillary microinjection into living cells
    • Ansorge W, Pepperkok R. Performance of an automated system for capillary microinjection into living cells. J Biochem Biophys Methods 16:283-292;1988.
    • (1988) J Biochem Biophys Methods , vol.16 , pp. 283-292
    • Ansorge, W.1    Pepperkok, R.2
  • 4
    • 0022409403 scopus 로고
    • Characterization of cells with high alkaline phosphatase activity derived from human bone and marrow: Preliminary assessment of their osteogenicity
    • Ashton BA, Abdullah F, Cave J, Williamson M, Sykes BC, Couch M, Poser JW. Characterization of cells with high alkaline phosphatase activity derived from human bone and marrow: Preliminary assessment of their osteogenicity. Bone 6:313-319;1985.
    • (1985) Bone , vol.6 , pp. 313-319
    • Ashton, B.A.1    Abdullah, F.2    Cave, J.3    Williamson, M.4    Sykes, B.C.5    Couch, M.6    Poser, J.W.7
  • 5
    • 0030826763 scopus 로고    scopus 로고
    • Monoclonal antibodies selective for human osteogenic cell surface antigens
    • Bruder SP, Horowitz MC, Haynesworth SE. Monoclonal antibodies selective for human osteogenic cell surface antigens. Bone 21:225-235;1997.
    • (1997) Bone , vol.21 , pp. 225-235
    • Bruder, S.P.1    Horowitz, M.C.2    Haynesworth, S.E.3
  • 6
    • 0031012465 scopus 로고    scopus 로고
    • Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following criopreservation
    • Bruder SP, Jaiswal N, Haynesworth SE. Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following criopreservation. J Cell Biochem 64: 278-294;1997.
    • (1997) J Cell Biochem , vol.64 , pp. 278-294
    • Bruder, S.P.1    Jaiswal, N.2    Haynesworth, S.E.3
  • 7
    • 0026228558 scopus 로고
    • Mesenchymal stem cells
    • Caplan AI. Mesenchymal stem cells. J Orthop Res 9:641-650;1991.
    • (1991) J Orthop Res , vol.9 , pp. 641-650
    • Caplan, A.I.1
  • 8
    • 0033770819 scopus 로고    scopus 로고
    • Mesenchymal stem cells and gene therapy
    • Caplan AI. Mesenchymal stem cells and gene therapy. Clin Orthop Res (379 suppl):S67-S70;2000.
    • (2000) Clin Orthop Res , Issue.379 SUPPL.
    • Caplan, A.I.1
  • 9
    • 0019191911 scopus 로고
    • High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
    • Capecchi M. High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22:479-488;1980.
    • (1980) Cell , vol.22 , pp. 479-488
    • Capecchi, M.1
  • 12
    • 0034743705 scopus 로고    scopus 로고
    • Targeted correction of defective selectable marker gene in human epithelial cells by small DNA fragments
    • Colosimo A, Gonecz KK, Novelli G, Dallapiccola B, Gruenert DC. Targeted correction of defective selectable marker gene in human epithelial cells by small DNA fragments. Mol Ther 3:178-185;2001.
    • (2001) Mol Ther , vol.3 , pp. 178-185
    • Colosimo, A.1    Gonecz, K.K.2    Novelli, G.3    Dallapiccola, B.4    Gruenert, D.C.5
  • 14
    • 0034651038 scopus 로고    scopus 로고
    • Microinjection-mediated delivery of macromolecules and transgenes to primary human blood stem/progenitor cells
    • Davis BR, Yannariello-Brown J, Prokopishyn NL, Wang J, Smith M, Lou ZJ, Brown DB. Microinjection-mediated delivery of macromolecules and transgenes to primary human blood stem/progenitor cells. Blood 95:437-444;2000.
    • (2000) Blood , vol.95 , pp. 437-444
    • Davis, B.R.1    Yannariello-Brown, J.2    Prokopishyn, N.L.3    Wang, J.4    Smith, M.5    Lou, Z.J.6    Brown, D.B.7
  • 16
    • 0030868484 scopus 로고    scopus 로고
    • Potent and selective gene inhibition using antisense oligodeoxynucleotides
    • Flanagan WM, Wagner RW. Potent and selective gene inhibition using antisense oligodeoxynucleotides. Mol Cell Biochem 172:213-225;1997.
    • (1997) Mol Cell Biochem , vol.172 , pp. 213-225
    • Flanagan, W.M.1    Wagner, R.W.2
  • 17
    • 0030839589 scopus 로고    scopus 로고
    • Capture and expansion of bone marrow-derived mesenchymal progenitor cells with a transforming growth factor-β1-von Willebrand's factor fusion protein for retrovirus-mediated delivery of coagulation factor IX
    • Gordon EM, Skotzko M, Kundu RK, Han B, Andrades J, Nimni M, Anderson F, Hall FL. Capture and expansion of bone marrow-derived mesenchymal progenitor cells with a transforming growth factor-β1-von Willebrand's factor fusion protein for retrovirus-mediated delivery of coagulation factor IX. Hum Gene Ther 8:1385-1394;1997.
    • (1997) Hum Gene Ther , vol.8 , pp. 1385-1394
    • Gordon, E.M.1    Skotzko, M.2    Kundu, R.K.3    Han, B.4    Andrades, J.5    Nimni, M.6    Anderson, F.7    Hall, F.L.8
  • 18
    • 84990622726 scopus 로고
    • Bone marrow osteogenic stem cells: In vitro cultivation and transplantation in diffusion chambers
    • Friedenstein AJ, Chailakhyan RK, Gerasimov UV. Bone marrow osteogenic stem cells: In vitro cultivation and transplantation in diffusion chambers. Cell Tissue Kinet 20:263-272;1987.
    • (1987) Cell Tissue Kinet , vol.20 , pp. 263-272
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Gerasimov, U.V.3
  • 20
    • 0033987325 scopus 로고    scopus 로고
    • Site-directed alteration of genomic DNA by small-fragment homologous replacement
    • Goncz KK, Gruenert DC. Site-directed alteration of genomic DNA by small-fragment homologous replacement. Methods Mol Biol 133:85-99;2000.
    • (2000) Methods Mol Biol , vol.133 , pp. 85-99
    • Goncz, K.K.1    Gruenert, D.C.2
  • 21
    • 0032844859 scopus 로고    scopus 로고
    • Opportunities and challenges in targeting genes for therapy
    • Gruenert DC. Opportunities and challenges in targeting genes for therapy. Gene Ther 6:1347-1348;1999.
    • (1999) Gene Ther , vol.6 , pp. 1347-1348
    • Gruenert, D.C.1
  • 22
    • 0026578530 scopus 로고
    • Characterization of cells with osteogenic potential from human marrow
    • Haynesworth SE, Goshima J, Goldberg VM, Caplan AI. Characterization of cells with osteogenic potential from human marrow. Bone 13:81-88;1992.
    • (1992) Bone , vol.13 , pp. 81-88
    • Haynesworth, S.E.1    Goshima, J.2    Goldberg, V.M.3    Caplan, A.I.4
  • 23
    • 0010241877 scopus 로고
    • Characterization of the unique mesenchymal stem cell phenotype in vitro
    • Haynesworth SE, Baber MA, Caplan AI. Characterization of the unique mesenchymal stem cell phenotype in vitro. Trans Orthop Res Soc 29:641-649;1995.
    • (1995) Trans Orthop Res Soc , vol.29 , pp. 641-649
    • Haynesworth, S.E.1    Baber, M.A.2    Caplan, A.I.3
  • 25
    • 0022372890 scopus 로고
    • Microinjected ras family oncogenes stimulate DNA synthesis in quiescent mammalian cells
    • Hyland JK, Rogers CM, Scolnick EM, Stein RB, Ellis R, Baserga R. Microinjected ras family oncogenes stimulate DNA synthesis in quiescent mammalian cells. Virology 141:333-336;1985.
    • (1985) Virology , vol.141 , pp. 333-336
    • Hyland, J.K.1    Rogers, C.M.2    Scolnick, E.M.3    Stein, R.B.4    Ellis, R.5    Baserga, R.6
  • 26
    • 0031012411 scopus 로고    scopus 로고
    • Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro
    • Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP. Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem 64:295-312;1997.
    • (1997) J Cell Biochem , vol.64 , pp. 295-312
    • Jaiswal, N.1    Haynesworth, S.E.2    Caplan, A.I.3    Bruder, S.P.4
  • 27
    • 0031817577 scopus 로고    scopus 로고
    • In vitro chondrogenesis of bone marrow-derived mesenchymal cells
    • Johnstone B, Yoo JU, Barry F. In vitro chondrogenesis of bone marrow-derived mesenchymal cells. Exp Cell Res 238:265-272;1998.
    • (1998) Exp Cell Res , vol.238 , pp. 265-272
    • Johnstone, B.1    Yoo, J.U.2    Barry, F.3
  • 28
    • 0034577858 scopus 로고    scopus 로고
    • Targeted gene repair in mammalian cells using chimeric oligonucleotides
    • Kmiec EB, Ye S, Peng L. Targeted gene repair in mammalian cells using chimeric oligonucleotides. Genet Eng 22:23-31;2000.
    • (2000) Genet Eng , vol.22 , pp. 23-31
    • Kmiec, E.B.1    Ye, S.2    Peng, L.3
  • 29
    • 0020413467 scopus 로고
    • Tissues and stem cells
    • Lajtha LG. Tissues and stem cells. Biomed Pharmacother 36:231-233;1982.
    • (1982) Biomed Pharmacother , vol.36 , pp. 231-233
    • Lajtha, L.G.1
  • 30
    • 0030842531 scopus 로고    scopus 로고
    • Microinjection of antibodies into mammalian cells
    • Lamb NJC, Fernandez A. Microinjection of antibodies into mammalian cells. Methods Enzymol 283:72-83;1997.
    • (1997) Methods Enzymol , vol.283 , pp. 72-83
    • Lamb, N.J.C.1    Fernandez, A.2
  • 31
    • 0028881201 scopus 로고
    • Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): Implication for therapeutic use
    • Lazarus H, Haynesworth SE, Gerson S, Rosenthal N, Caplan AI. Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): Implication for therapeutic use. Bone Marrow Transplant 16:557-564;1995.
    • (1995) Bone Marrow Transplant , vol.16 , pp. 557-564
    • Lazarus, H.1    Haynesworth, S.E.2    Gerson, S.3    Rosenthal, N.4    Caplan, A.I.5
  • 32
    • 0021182442 scopus 로고
    • Transient complementation of Xeroderma pigmentosum cells by microinjection of poly (A)+RNA
    • Legerski RJ, Brown DB, Peterson CA, Robberson DL. Transient complementation of Xeroderma pigmentosum cells by microinjection of poly (A)+RNA. Proc Natl Acad Sci USA 81: 5676-5679;1984.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5676-5679
    • Legerski, R.J.1    Brown, D.B.2    Peterson, C.A.3    Robberson, D.L.4
  • 33
    • 0030459866 scopus 로고    scopus 로고
    • Human and animal mesenchymal progenitor cells from bone marrow: Identification of serum for optimal selection and proliferation
    • Lennon DP, Haynesworth SE, Bruder SP, Jaiswal N, Caplan AI. Human and animal mesenchymal progenitor cells from bone marrow: Identification of serum for optimal selection and proliferation. In Vitro Cell Dev Biol 32:602-611;1996.
    • (1996) In Vitro Cell Dev Biol , vol.32 , pp. 602-611
    • Lennon, D.P.1    Haynesworth, S.E.2    Bruder, S.P.3    Jaiswal, N.4    Caplan, A.I.5
  • 34
    • 0035886376 scopus 로고    scopus 로고
    • In vivo gene repair of point and frame shift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides
    • Liu L, Rice MC, Kmiec EB. In vivo gene repair of point and frame shift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides. Nucleic Acids Res 29:4238-4250;2001.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4238-4250
    • Liu, L.1    Rice, M.C.2    Kmiec, E.B.3
  • 36
    • 0031861531 scopus 로고    scopus 로고
    • Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells
    • Majumdar MK, Thiede MA, Mosca JD, Moorman M, Gerson SL. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. J Cell Physiol 176:57-66;1998.
    • (1998) J Cell Physiol , vol.176 , pp. 57-66
    • Majumdar, M.K.1    Thiede, M.A.2    Mosca, J.D.3    Moorman, M.4    Gerson, S.L.5
  • 38
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller DG, Adam MA, Miller AD. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol 10:4239-4242;1990.
    • (1990) Mol Cell Biol , vol.10 , pp. 4239-4242
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 39
    • 0025610469 scopus 로고
    • Analysis of cis-acting promoter elements using microinjected synthetic oligonucleotides
    • Miskimins WK, Brown DB. Analysis of cis-acting promoter elements using microinjected synthetic oligonucleotides. Exp Cell Res 191:328-331;1990.
    • (1990) Exp Cell Res , vol.191 , pp. 328-331
    • Miskimins, W.K.1    Brown, D.B.2
  • 41
    • 0026197325 scopus 로고
    • Culture-expanded human periosteal-derived cells exhibit osteochondral potential in vivo
    • Nakahara H, Goldberg V, Caplan AI. Culture-expanded human periosteal-derived cells exhibit osteochondral potential in vivo. J Orthop Res 9:465-478;1991.
    • (1991) J Orthop Res , vol.9 , pp. 465-478
    • Nakahara, H.1    Goldberg, V.2    Caplan, A.I.3
  • 42
    • 0027325195 scopus 로고
    • Differentiation and proliferation of hematopoietic stem cells
    • Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood 81:2844-2853;1993.
    • (1993) Blood , vol.81 , pp. 2844-2853
    • Ogawa, M.1
  • 43
    • 0023746658 scopus 로고
    • Single cell assay with an automated capillary microinjection system
    • Pepperkok R, Schneider C, Philipson L, Ansorge W. Single cell assay with an automated capillary microinjection system. Exp Cell Res 178:369-376;1988.
    • (1988) Exp Cell Res , vol.178 , pp. 369-376
    • Pepperkok, R.1    Schneider, C.2    Philipson, L.3    Ansorge, W.4
  • 45
    • 0033818214 scopus 로고    scopus 로고
    • Human mesenchymal stem cells: Progenitor cells for cartilage, bone, fat and stroma
    • Pittenger MF, Mosca JD, Mcintosh KR. Human mesenchymal stem cells: Progenitor cells for cartilage, bone, fat and stroma. Curr Top Microbiol Immunol 251:3-11;2000.
    • (2000) Curr Top Microbiol Immunol , vol.251 , pp. 3-11
    • Pittenger, M.F.1    Mosca, J.D.2    Mcintosh, K.R.3
  • 46
    • 0000858105 scopus 로고    scopus 로고
    • Human mesenchymal stem cells can be directed into chondrocytes, adipocytes and osteocytes
    • abstract 1772
    • Pittenger MF, Mackay AM, Beck SC. Human mesenchymal stem cells can be directed into chondrocytes, adipocytes and osteocytes (abstract 1772). Mol Biol Cell 7:305;1996.
    • (1996) Mol Biol Cell , vol.7 , pp. 305
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 47
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for non-hematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for non-hematopoietic tissues. Science 276:71-75;1997.
    • (1997) Science , vol.276 , pp. 71-75
    • Prockop, D.J.1
  • 48
    • 0033453222 scopus 로고    scopus 로고
    • Positional enhancer-blocking activity of the chicken beta-globin insulator in transiently transfected cells
    • Recillas-Targa F, Bell AC, Felsenfeld G. Positional enhancer-blocking activity of the chicken beta-globin insulator in transiently transfected cells. Proc Natl Acad Sci USA 96:14354-14357;1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14354-14357
    • Recillas-Targa, F.1    Bell, A.C.2    Felsenfeld, G.3
  • 49
    • 0035069295 scopus 로고    scopus 로고
    • The potential of nucleic acid repair in functional genomics
    • Rice MC, Czymmek K, Kmiec EB. The potential of nucleic acid repair in functional genomics. Nat Biotechnol 19:321-326;2001.
    • (2001) Nat Biotechnol , vol.19 , pp. 321-326
    • Rice, M.C.1    Czymmek, K.2    Kmiec, E.B.3
  • 50
    • 0034284778 scopus 로고    scopus 로고
    • Therapeutic approaches to bone diseases. Tissue engineers build new bone
    • Rodan G, Martin TJ. Therapeutic approaches to bone diseases. Tissue engineers build new bone. Science 289:1498-1500,1508-1514;2000.
    • (2000) Science , vol.289 , pp. 1498-1500
    • Rodan, G.1    Martin, T.J.2
  • 51
    • 0034328925 scopus 로고    scopus 로고
    • Gene therapy: Trials and tribulations
    • Somia N, Verma IM. Gene therapy: Trials and tribulations. Nat Rev Genet 1:91-99;2001.
    • (2001) Nat Rev Genet , vol.1 , pp. 91-99
    • Somia, N.1    Verma, I.M.2
  • 52
    • 0019751833 scopus 로고
    • Microinjection of mRNA and other macromolecules into living cells
    • Stacey D. Microinjection of mRNA and other macromolecules into living cells. Methods Enzymol 79:76-88;1981.
    • (1981) Methods Enzymol , vol.79 , pp. 76-88
    • Stacey, D.1
  • 53
    • 0021184853 scopus 로고
    • Transformation of NIH 3T3 cells by microinjection of Ha-rasp 21 protein
    • Stacey DW, Hsiang-Fu K. Transformation of NIH 3T3 cells by microinjection of Ha-rasp21 protein. Nature 310:508-511;1984.
    • (1984) Nature , vol.310 , pp. 508-511
    • Stacey, D.W.1    Hsiang-Fu, K.2
  • 55
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy - Promises, problems and prospects
    • Verma IM, Somia N. Gene therapy - Promises, problems and prospects. Nature 389:239-242;1997.
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.