Preparation and characterization of polyethylene-glycol-modified salmon calcitonins

Pharmaceutical Development and Technology

Volumn 4, Issue 2, 1999, Pages 269-275

  Lee, Kang Choon ^a   Tak, Kyung Kook ^a   Park, Myung Ok ^a   Lee, Jung Tae ^a   Woo, Byung Ho ^a   Yoo, Sun Dong ^a   Lee, Hye Suk ^b   DeLuca, Patrick P ^c  

^a Sungkyunkwan University   (South Korea)

^b Wonkwang University   (South Korea)

^c University of Kentucky   (United States)

Author keywords

Bioconjugation; Blood clearance; cAMP assay; Matrix assisted laser desorption ionization time of flight (MALDI TOF) mass spectrometry; PEGylation; Polyethylene glycol; Salmon calcitonin; Stability

Indexed keywords

CYCLIC AMP; MACROGOL DERIVATIVE; SALCATONIN; SUCCINIMIDYL CARBONATE MONOMETHOXYPOLYETHYLENE GLYCOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DEGRADATION; DRUG HALF LIFE; DRUG PURIFICATION; DRUG STABILITY; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; OSTEOSARCOMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT;

AMINO ACID SEQUENCE; ANIMALS; CALCITONIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIC AMP; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; MALE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0000981509     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-100101361     Document Type: Article

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