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Volumn 58, Issue SUPPL. 1, 1999, Pages

PEGylated recombinant human soluble tumour necrosis factor receptor type I (r-Hu-sTNF-RI): Novel high affinity TNF receptor designed for chronic inflammatory diseases

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; MACROGOL; STAPHYLOCOCCUS ENTEROTOXIN B; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0032725837     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (88)

References (74)
  • 2
    • 0028801694 scopus 로고
    • TNF and Mae West or: Death from too much of a good thing
    • commentary
    • Tracey KJ. TNF and Mae West or: death from too much of a good thing. Lancet [commentary]. 1995;345:75-6.
    • (1995) Lancet , vol.345 , pp. 75-76
    • Tracey, K.J.1
  • 3
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • Bazzoni F, Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med 1996;334:1717-25.
    • (1996) N Engl J Med , vol.334 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 5
    • 0030803513 scopus 로고    scopus 로고
    • Anticytokine therapy in rheumatoid arthritis
    • Firestein GS, Zvaifler N. Anticytokine therapy in rheumatoid arthritis. N Engl J Med 1997;337:195-7.
    • (1997) N Engl J Med , vol.337 , pp. 195-197
    • Firestein, G.S.1    Zvaifler, N.2
  • 6
    • 0024405827 scopus 로고
    • The biology of cachectin/TNF - A primary mediator of the host response
    • Beutler B, Cerami A. The biology of cachectin/TNF - a primary mediator of the host response. Annu Rev Immunol 1989;7:625-55.
    • (1989) Annu Rev Immunol , vol.7 , pp. 625-655
    • Beutler, B.1    Cerami, A.2
  • 8
    • 0028043394 scopus 로고
    • Protective effect of 55-Kd but not 75-Kd soluble tumor-necrosis-factor receptor immunoglobulin-G fusion proteins in an animal-model of Gram-negative sepsis
    • Evans TJ, Moyes D, Carpenter A, et al. Protective effect of 55-Kd but not 75-Kd soluble tumor-necrosis-factor receptor immunoglobulin-G fusion proteins in an animal-model of Gram-negative sepsis. J Exp Med 1994;180:2173-9.
    • (1994) J Exp Med , vol.180 , pp. 2173-2179
    • Evans, T.J.1    Moyes, D.2    Carpenter, A.3
  • 9
    • 0029900294 scopus 로고    scopus 로고
    • Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein
    • Fisher Jr CJ, Agosti JM, Opal SM, et al. Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein. N Engl J Med 1996;334:1697-702.
    • (1996) N Engl J Med , vol.334 , pp. 1697-1702
    • Fisher C.J., Jr.1    Agosti, J.M.2    Opal, S.M.3
  • 10
    • 0032922359 scopus 로고    scopus 로고
    • The role of tumor necrosis factor in health and disease
    • Beutler BA. The role of tumor necrosis factor in health and disease. J Rheumatol 1999;26:16-21.
    • (1999) J Rheumatol , vol.26 , pp. 16-21
    • Beutler, B.A.1
  • 12
    • 0028277663 scopus 로고
    • Unraveling function in the TNF ligand and receptor families
    • Beutler B, Van Huffel C. Unraveling function in the TNF ligand and receptor families. Science 1994;264:667-709.
    • (1994) Science , vol.264 , pp. 667-709
    • Beutler, B.1    Van Huffel, C.2
  • 13
    • 0027211704 scopus 로고
    • Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
    • Banner DW, D'Arcy A, Janes W, et al. Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell 1993;73:431-45.
    • (1993) Cell , vol.73 , pp. 431-445
    • Banner, D.W.1    D'Arcy, A.2    Janes, W.3
  • 14
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993;75:1169-78.
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 15
    • 0031882913 scopus 로고    scopus 로고
    • The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
    • Grell M, Wajant H, Zimmerman G, Scheurich P. The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor. Proc Natl Acad Sci USA 1998,95: 570-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 570-575
    • Grell, M.1    Wajant, H.2    Zimmerman, G.3    Scheurich, P.4
  • 16
    • 0033560764 scopus 로고    scopus 로고
    • A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'
    • Watts AD, Hunt NH, Wanigasekara Y, et al. A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'. EMBO J 1999;18:2119-26.
    • (1999) EMBO J , vol.18 , pp. 2119-2126
    • Watts, A.D.1    Hunt, N.H.2    Wanigasekara, Y.3
  • 17
    • 0029265441 scopus 로고
    • Soluble tumor necrosis factor receptors in arthritis
    • Cope AP, Maini RN. Soluble tumor necrosis factor receptors in arthritis. J. Rheumatol. 1995;22:382-4.
    • (1995) J. Rheumatol. , vol.22 , pp. 382-384
    • Cope, A.P.1    Maini, R.N.2
  • 18
    • 0025096274 scopus 로고
    • A second tumor necrosis factor gene product can yield a naturally occuring tumor necrosis factor inhibitor
    • Kohno T, Brewer MT, Baker SL, et al. A second tumor necrosis factor gene product can yield a naturally occuring tumor necrosis factor inhibitor. Proc Natl Acad Sci USA 1990;87:8331-5.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8331-8335
    • Kohno, T.1    Brewer, M.T.2    Baker, S.L.3
  • 19
    • 0026741275 scopus 로고
    • Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo
    • Van Zee KJ, Kohno T, Fischer E, Rock CS, Moldawer LL, Lowry SF. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. Proc Natl Acad Sci USA 1992;89:4845-9.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4845-4849
    • Van Zee, K.J.1    Kohno, T.2    Fischer, E.3    Rock, C.S.4    Moldawer, L.L.5    Lowry, S.F.6
  • 20
    • 0033019404 scopus 로고    scopus 로고
    • Animal models of arthritis: Relevance to human disease
    • Bendele A, McComb J, Gould T, et al. Animal models of arthritis: relevance to human disease. Toxicol Pathol 1999; 27:134-42.
    • (1999) Toxicol Pathol , vol.27 , pp. 134-142
    • Bendele, A.1    McComb, J.2    Gould, T.3
  • 21
    • 0032873289 scopus 로고    scopus 로고
    • Combination benefit of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) and dexamethasone or indomethacin in adjuvant arthritic rats
    • Bendele AM, McComb J, Gould T, et al. Combination benefit of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) and dexamethasone or indomethacin in adjuvant arthritic rats. Inflamm Res 1999;48:453-60.
    • (1999) Inflamm Res , vol.48 , pp. 453-460
    • Bendele, A.M.1    McComb, J.2    Gould, T.3
  • 22
    • 0032884904 scopus 로고    scopus 로고
    • Effects of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) alone ands in combination with methotrexate in adjuvant arthritic rats
    • in press
    • Bendele AM, McComb J, Gould T, et al. Effects of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) alone ands in combination with methotrexate in adjuvant arthritic rats. Clin Exp Rheumatol (in press).
    • Clin Exp Rheumatol
    • Bendele, A.M.1    McComb, J.2    Gould, T.3
  • 23
    • 0033067522 scopus 로고    scopus 로고
    • Anti-arthritic activity of soluble TNF receptor forms in adjuvant arthritis: Correlation of plasma levels with efficacy
    • McComb J, Gould T, Chlipala E, et al. Anti-arthritic activity of soluble TNF receptor forms in adjuvant arthritis: correlation of plasma levels with efficacy. J Rheumatol 1999;26:1347-51.
    • (1999) J Rheumatol , vol.26 , pp. 1347-1351
    • McComb, J.1    Gould, T.2    Chlipala, E.3
  • 24
    • 0028143211 scopus 로고
    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10.
    • (1994) Lancet , vol.344 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 25
    • 0027438710 scopus 로고
    • Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha
    • Elliott MJ, Maini RN, Feldmann M, et al. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 1993;36: 1681-90.
    • (1993) Arthritis Rheum , vol.36 , pp. 1681-1690
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 26
    • 0028143212 scopus 로고
    • Repeated therapy with monoclonal-antibody to tumor necrosis factor alpha (cA2) in patients with rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, et al. Repeated therapy with monoclonal-antibody to tumor necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet 1994;344:1125-7.
    • (1994) Lancet , vol.344 , pp. 1125-1127
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 27
    • 15144359413 scopus 로고    scopus 로고
    • Pharmacokinetics, immunogenicity and efficacy of dimeric TNFR binding proteins in healthy and bacteremic baboon
    • Solorzano C, Kaibara A, Hess PJ, et al. Pharmacokinetics, immunogenicity and efficacy of dimeric TNFR binding proteins in healthy and bacteremic baboon. J Appl Physiol 1998;84:1119-30.
    • (1998) J Appl Physiol , vol.84 , pp. 1119-1130
    • Solorzano, C.1    Kaibara, A.2    Hess, P.J.3
  • 28
    • 0031982531 scopus 로고    scopus 로고
    • Soluble TNF receptor prevents arthritis and pneumonitis in motheaten mice
    • Yang SP, Edwards III CK, Mountz JD. Soluble TNF receptor prevents arthritis and pneumonitis in motheaten mice. Arthritis Rheum 1998;41:139-49.
    • (1998) Arthritis Rheum , vol.41 , pp. 139-149
    • Yang, S.P.1    Edwards C.K. III2    Mountz, J.D.3
  • 29
    • 0001182063 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor (TNF) is effective alone or in combination with inhibition of interleukin-1 (IL-1) in reducing joint swelling in rodent bacterial cell wall-induced arthritis
    • Russell D, Tucker H, Kohno H, Thompson RC. Inhibition of tumor necrosis factor (TNF) is effective alone or in combination with inhibition of interleukin-1 (IL-1) in reducing joint swelling in rodent bacterial cell wall-induced arthritis. Arthritis Rheum 1996;37:s279.
    • (1996) Arthritis Rheum , vol.37
    • Russell, D.1    Tucker, H.2    Kohno, H.3    Thompson, R.C.4
  • 30
    • 0029165243 scopus 로고
    • PEG-BP-30 mono-therapy attenuates the cytokine-mediated inflammatory cascade in baboon Escherichia coli septic shuck
    • Espat NJ, Cendan JC, Beierle EA, et al. PEG-BP-30 mono-therapy attenuates the cytokine-mediated inflammatory cascade in baboon Escherichia coli septic shuck. J Surg Res 1995;59:153-8.
    • (1995) J Surg Res , vol.59 , pp. 153-158
    • Espat, N.J.1    Cendan, J.C.2    Beierle, E.A.3
  • 31
    • 0030638944 scopus 로고    scopus 로고
    • Involvement of 26-kDa cell associated TNFμ in experimental hepatitis and exacerbation of liver injury with a matrix metalloproteinase inhibitor
    • Solorzano CC, Ksontini R, Pruitt JH, et al. Involvement of 26-kDa cell associated TNFμ in experimental hepatitis and exacerbation of liver injury with a matrix metalloproteinase inhibitor. J Immunol 1997;158:414-19.
    • (1997) J Immunol , vol.158 , pp. 414-419
    • Solorzano, C.C.1    Ksontini, R.2    Pruitt, J.H.3
  • 32
    • 0029958555 scopus 로고    scopus 로고
    • The clinical relevance of circulating tumor necrosis factor-alpha in acute decompensated chronic heart failure without cachexia
    • Milani RV, Mehra MR, Endres S, et al. The clinical relevance of circulating tumor necrosis factor-alpha in acute decompensated chronic heart failure without cachexia. Chest 1996;110:992-5.
    • (1996) Chest , vol.110 , pp. 992-995
    • Milani, R.V.1    Mehra, M.R.2    Endres, S.3
  • 34
    • 13344270905 scopus 로고    scopus 로고
    • Protection against lethal escherichia bacteremia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081
    • Van Zee KJ, Moldawer LL, Oldenburg HS, et al. Protection against lethal Escherichia bacteremia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081. J Immunol 1996;156:2221-30.
    • (1996) J Immunol , vol.156 , pp. 2221-2230
    • Van Zee, K.J.1    Moldawer, L.L.2    Oldenburg, H.S.3
  • 36
    • 8244235133 scopus 로고    scopus 로고
    • P55 tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock. A randomized controlled multicenter trial
    • Abraham E, Glauser MP, Butler T, et al. p55 tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock. A randomized controlled multicenter trial. JAMA 1997;277:1531-8.
    • (1997) JAMA , vol.277 , pp. 1531-1538
    • Abraham, E.1    Glauser, M.P.2    Butler, T.3
  • 37
    • 0032945382 scopus 로고    scopus 로고
    • Inhibitors of tumor necrosis factor for rheumatoid arthritis
    • Moreland LW. Inhibitors of tumor necrosis factor for rheumatoid arthritis. J Rheumatol 1999;26:7-15.
    • (1999) J Rheumatol , vol.26 , pp. 7-15
    • Moreland, L.W.1
  • 38
    • 0026516744 scopus 로고
    • Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
    • Aderka D, Engelmann H, Maor Y, Brakebusch C, Wallach D. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J Exp Med 1992;175:323-9.
    • (1992) J Exp Med , vol.175 , pp. 323-329
    • Aderka, D.1    Engelmann, H.2    Maor, Y.3    Brakebusch, C.4    Wallach, D.5
  • 39
    • 0027198002 scopus 로고
    • Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists
    • Mohler KM, Torrance DS, Smith CA, et al. Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J Immunol 1993;151:1548-61.
    • (1993) J Immunol , vol.151 , pp. 1548-1561
    • Mohler, K.M.1    Torrance, D.S.2    Smith, C.A.3
  • 40
    • 0027301244 scopus 로고
    • Ligand passing: The 75-Kd tumor necrosis factor (TNF) receptor recrutis TNF for signaling by the 55 Kd TNF receptor
    • Tartaglia IA, Pennica D, Goeddel DV. Ligand passing: the 75-Kd tumor necrosis factor (TNF) receptor recrutis TNF for signaling by the 55 Kd TNF receptor. J Biol Chem 1993;268:18542-8.
    • (1993) J Biol Chem , vol.268 , pp. 18542-18548
    • Tartaglia, I.A.1    Pennica, D.2    Goeddel, D.V.3
  • 41
    • 0031955230 scopus 로고    scopus 로고
    • Revisiting the role of tumor necrosis factor alpha and the response to surgical injury and inflammation
    • Ksontini R, MacKay SL, Moldawer LL. Revisiting the role of tumor necrosis factor alpha and the response to surgical injury and inflammation. Arch Surg 1999;133:558-67.
    • (1999) Arch Surg , vol.133 , pp. 558-567
    • Ksontini, R.1    Mackay, S.L.2    Moldawer, L.L.3
  • 42
    • 0030698252 scopus 로고    scopus 로고
    • TNF inhibition and sepsis-sounding a cautionary note
    • Grau G E, Maennel DN. TNF inhibition and sepsis-sounding a cautionary note. Nat Med 1997;3:1193-5.
    • (1997) Nat Med , vol.3 , pp. 1193-1195
    • Grau G, E.1    Maennel, D.N.2
  • 43
    • 0032996860 scopus 로고    scopus 로고
    • Biologic agents in the treatment of inflammatory rheumatic diseases
    • Lorenz HM, Kalden JR. Biologic agents in the treatment of inflammatory rheumatic diseases. Curr Opin Rheumatol 1999;11:179-84.
    • (1999) Curr Opin Rheumatol , vol.11 , pp. 179-184
    • Lorenz, H.M.1    Kalden, J.R.2
  • 44
    • 0028574382 scopus 로고
    • Interleukin-I, tumor necrosis factor and their specific inhibitors
    • Dayer J, Burger D, Interleukin-I, tumor necrosis factor and their specific inhibitors. European Cytokine Review 1994;5:563-71.
    • (1994) European Cytokine Review , vol.5 , pp. 563-571
    • Dayer, J.1    Burger, D.2
  • 45
    • 0025274640 scopus 로고
    • Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis
    • Arend WP, Dayer JM. Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 1990; 33:305-15.
    • (1990) Arthritis Rheum , vol.33 , pp. 305-315
    • Arend, W.P.1    Dayer, J.M.2
  • 46
    • 0028861236 scopus 로고
    • Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis
    • Arend WP, Dayer JM. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum 1995;38:151-60.
    • (1995) Arthritis Rheum , vol.38 , pp. 151-160
    • Arend, W.P.1    Dayer, J.M.2
  • 47
    • 0032401777 scopus 로고    scopus 로고
    • Regulation of autoimmunity by proinflammatory cytokines
    • Cope AP. Regulation of autoimmunity by proinflammatory cytokines. Curr Opin Immunol 1998;10:669-76.
    • (1998) Curr Opin Immunol , vol.10 , pp. 669-676
    • Cope, A.P.1
  • 48
    • 0025099962 scopus 로고
    • Cytokine production in the rheumatoid joint: Implications for treatment
    • Feldmann M, Brennan FM, Chantry D, et al. Cytokine production in the rheumatoid joint: implications for treatment. Ann Rheum Dis 1990;49:480-6.
    • (1990) Ann Rheum Dis , vol.49 , pp. 480-486
    • Feldmann, M.1    Brennan, F.M.2    Chantry, D.3
  • 49
    • 0344782280 scopus 로고    scopus 로고
    • DBA/1 mice expressing the human TNF-alpha transgene develop a severe, erosive arthritis
    • Butler DM, Malfait A, Mason LJ, et al. DBA/1 mice expressing the human TNF-alpha transgene develop a severe, erosive arthritis. J Immunol 1997;159:2876.
    • (1997) J Immunol , vol.159 , pp. 2876
    • Butler, D.M.1    Malfait, A.2    Mason, L.J.3
  • 50
    • 0033030206 scopus 로고    scopus 로고
    • Distribution of TNF-alpha, TNF-R55 and TNF-r75 in the rheumatoid synovial membrane: TNF receptors are localized preferentially in the lining layer; TNF-alpha is distributed mainly in the vicinity of TNF receptors in the deeper layers
    • Alsalameh S, Winter K, Al-Ward R, Wendler J, Kalden JR, Kinne RW. Distribution of TNF-alpha, TNF-R55 and TNF-R75 in the rheumatoid synovial membrane: TNF receptors are localized preferentially in the lining layer; TNF-alpha is distributed mainly in the vicinity of TNF receptors in the deeper layers. Scand J Immunol 1999;49: 278-85.
    • (1999) Scand J Immunol , vol.49 , pp. 278-285
    • Alsalameh, S.1    Winter, K.2    Al-Ward, R.3    Wendler, J.4    Kalden, J.R.5    Kinne, R.W.6
  • 51
    • 0028951168 scopus 로고
    • Multifunctional regulation of the biological effects of TNF-alpha by the soluble type I and type II TNF receptors
    • Hale KK, Smith CG, Baker SL, et al. Multifunctional regulation of the biological effects of TNF-alpha by the soluble type I and type II TNF receptors. Cytokine 1995;7:26-38.
    • (1995) Cytokine , vol.7 , pp. 26-38
    • Hale, K.K.1    Smith, C.G.2    Baker, S.L.3
  • 52
    • 0030760235 scopus 로고    scopus 로고
    • Concentration and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid
    • Desgeorges A, Gabay C, Silacci P, et al. Concentration and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid. J Rheumatol 1997;24:1510-16.
    • (1997) J Rheumatol , vol.24 , pp. 1510-1516
    • Desgeorges, A.1    Gabay, C.2    Silacci, P.3
  • 53
    • 0029077690 scopus 로고
    • TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: Evidence of feedback control of TNF action
    • Brennan FM, Gibbons DL, Cope AP, Katsikis P, Maini RN, Feldmann M. TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: evidence of feedback control of TNF action. Scand J Immunol 1995;42:158-65.
    • (1995) Scand J Immunol , vol.42 , pp. 158-165
    • Brennan, F.M.1    Gibbons, D.L.2    Cope, A.P.3    Katsikis, P.4    Maini, R.N.5    Feldmann, M.6
  • 54
    • 0029044362 scopus 로고
    • Preliminary definition of improvement in rheumatoid arthritis
    • American College of Rheumatology
    • Felson DT, Anderson JJ, Boers M, et al. American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995;38:727-35.
    • (1995) Arthritis Rheum , vol.38 , pp. 727-735
    • Felson, D.T.1    Anderson, J.J.2    Boers, M.3
  • 55
    • 0031680201 scopus 로고    scopus 로고
    • Should improvement in rheumatoid arthritis clinical trials be defined as fifty percent or seventy percent improvements in core set measures, rather than twenty percent?
    • Felson DT, Anderson JK, Lange ML, Wells C, LaValley MP. Should improvement in rheumatoid arthritis clinical trials be defined as fifty percent or seventy percent improvements in core set measures, rather than twenty percent? Arthritis Rheum 1998;41:1564-70.
    • (1998) Arthritis Rheum , vol.41 , pp. 1564-1570
    • Felson, D.T.1    Anderson, J.K.2    Lange, M.L.3    Wells, C.4    LaValley, M.P.5
  • 56
    • 0029837629 scopus 로고    scopus 로고
    • What is the mechanism of action of anti-tumour necrosis factor-alpha antibody in rheumatoid arthritis?
    • Feldmann M. What is the mechanism of action of anti-tumour necrosis factor-alpha antibody in rheumatoid arthritis? Int Arch Allergy Immunol 1996;111:362-5.
    • (1996) Int Arch Allergy Immunol , vol.111 , pp. 362-365
    • Feldmann, M.1
  • 58
    • 0030970232 scopus 로고    scopus 로고
    • TNF blockade in rheumatoid arthritis: Implications for therapy and pathogenesis
    • Maini RN, Elliott M, Brennan FM, Williams RO, Feldmann M. TNF blockade in rheumatoid arthritis: implications for therapy and pathogenesis. APMIS 1997;105:257-63.
    • (1997) APMIS , vol.105 , pp. 257-263
    • Maini, R.N.1    Elliott, M.2    Brennan, F.M.3    Williams, R.O.4    Feldmann, M.5
  • 60
    • 0344782279 scopus 로고    scopus 로고
    • Engineered human anti-tumor necrosis factor-alpha (TNFα) antibody, CDP571, in rheumatoid arthritis
    • Strand V, Scott DL, Simons LS, eds. New York, NY: Marcel Dekker
    • Choy EHS, Panayi GS. Engineered human anti-tumor necrosis factor-alpha (TNFα) antibody, CDP571, in rheumatoid arthritis. In: Strand V, Scott DL, Simons LS, eds. Novel therapeutic agents for the treatment of autoimmune diseases. New York, NY: Marcel Dekker, 1997:121-9.
    • (1997) Novel Therapeutic Agents for the Treatment of Autoimmune Diseases , pp. 121-129
    • Choy, E.H.S.1    Panayi, G.S.2
  • 61
    • 0031774035 scopus 로고    scopus 로고
    • Clinical trials on biologies in rheumatoid arthritis
    • Sander O, Rau R. Clinical trials on biologies in rheumatoid arthritis. Int J Clin Pharmacol Ther 1998;36:621-4.
    • (1998) Int J Clin Pharmacol Ther , vol.36 , pp. 621-624
    • Sander, O.1    Rau, R.2
  • 62
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • Moreland LW, Baumgartner SW, Schiff MH, et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 1997;337:141-7.
    • (1997) N Engl J Med , vol.337 , pp. 141-147
    • Moreland, L.W.1    Baumgartner, S.W.2    Schiff, M.H.3
  • 63
    • 0033574147 scopus 로고    scopus 로고
    • Etanercept therapy in rheumatoid arthritis: A randomized, controlled trial
    • Moreland LW, Schiff MH, Baumgartner SW, et al. Etanercept therapy in rheumatoid arthritis: A randomized, controlled trial. Ann Intern Med 1999;130:478-86.
    • (1999) Ann Intern Med , vol.130 , pp. 478-486
    • Moreland, L.W.1    Schiff, M.H.2    Baumgartner, S.W.3
  • 64
    • 0030996312 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha therapy of rheumatoid arthritis
    • Feldmann M, Elliott MJ, Woody JN, Maini RN. Anti-tumor necrosis factor-alpha therapy of rheumatoid arthritis. Adv Immunol 1996;64:283-350.
    • (1996) Adv Immunol , vol.64 , pp. 283-350
    • Feldmann, M.1    Elliott, M.J.2    Woody, J.N.3    Maini, R.N.4
  • 65
    • 0005300697 scopus 로고    scopus 로고
    • Recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer (TNFbp Dimer) in patients with active refractory rheumatoid arthritis
    • in press
    • Moreland LW, McCabe D, Caldwell JR, et al. Recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer (TNFbp Dimer) in patients with active refractory rheumatoid arthritis. J Rheumatol (in press).
    • J Rheumatol
    • Moreland, L.W.1    McCabe, D.2    Caldwell, J.R.3
  • 66
    • 0013428011 scopus 로고    scopus 로고
    • Assessment of the major antigenic epitopes of the recombinant human soluble p55 TNF type I receptor: Design of a novel mono-meric non-immunogenic analog, sTNF-RI
    • Edwards III CK, Frazier J, Seely J, et al. Assessment of the major antigenic epitopes of the recombinant human soluble p55 TNF type I receptor: design of a novel mono-meric non-immunogenic analog, sTNF-RI. Arthritis Rheum 1998;41:S58..
    • (1998) Arthritis Rheum , vol.41
    • Edwards C.K. III1    Frazier, J.2    Seely, J.3
  • 67
    • 0027181961 scopus 로고
    • Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge
    • Parmely MJ, Zhou WW, Edwards III CK, Borcherding DR, Silverstein R, Morrison DC. Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge. J Immunol 1993;151:389-96.
    • (1993) J Immunol , vol.151 , pp. 389-396
    • Parmely, M.J.1    Zhou, W.W.2    Edwards C.K. III3    Borcherding, D.R.4    Silverstein, R.5    Morrison, D.C.6
  • 68
    • 0029145145 scopus 로고
    • The inhibitory activity of human interleukin-1 receptor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor
    • Burger D, Chicheportiche R, Giri JG, Dayer J. The inhibitory activity of human interleukin-1 receptor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor. J Clin Invest 1995;96:38-41.
    • (1995) J Clin Invest , vol.96 , pp. 38-41
    • Burger, D.1    Chicheportiche, R.2    Giri, J.G.3    Dayer, J.4
  • 69
    • 0022369449 scopus 로고
    • Reactivation of streptococcal cell wall-induced arthritis by homologous cell wall polymers
    • Esser RE, Stimpson SA, Cromartie WJ, Schwab JH. Reactivation of streptococcal cell wall-induced arthritis by homologous cell wall polymers. Arthritis Rheum 1985;28: 1402-11.
    • (1985) Arthritis Rheum , vol.28 , pp. 1402-1411
    • Esser, R.E.1    Stimpson, S.A.2    Cromartie, W.J.3    Schwab, J.H.4
  • 70
    • 0001649520 scopus 로고    scopus 로고
    • Efficacy of tumor necrosis factor binding protein (TNF-bp) in the streptococcal cell wall-induced reactivation model of arthritis
    • Evans RJ, Bendele AM, Kieft GI, McAbee TJ, Edwards III CK. Efficacy of tumor necrosis factor binding protein (TNF-bp) in the streptococcal cell wall-induced reactivation model of arthritis. Arthritis Rheum 1996;39:S284.
    • (1996) Arthritis Rheum , vol.39
    • Evans, R.J.1    Bendele, A.M.2    Kieft, G.I.3    McAbee, T.J.4    Edwards C.K. III5
  • 71
    • 0033016267 scopus 로고    scopus 로고
    • Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis
    • Bendele A, McAbee T, Sennello G, Frazier J, Chlipala E, McCabe D. Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis. Arthritis Rheum 1999;42:498-506.
    • (1999) Arthritis Rheum , vol.42 , pp. 498-506
    • Bendele, A.1    McAbee, T.2    Sennello, G.3    Frazier, J.4    Chlipala, E.5    McCabe, D.6
  • 72
    • 0003119619 scopus 로고    scopus 로고
    • A genetically modified tumor necrosis factor receptor I (sTNF-RI) that does not elicit antibody response in primates
    • Martin S, Frazier J, Seely J, et al. A genetically modified tumor necrosis factor receptor I (sTNF-RI) that does not elicit antibody response in primates. Arthritis Rheum 1998;41:S58.
    • (1998) Arthritis Rheum , vol.41
    • Martin, S.1    Frazier, J.2    Seely, J.3
  • 73
    • 0344350346 scopus 로고    scopus 로고
    • The pharmacokinetics of subcutaneous injections of PEGylated recombinant methiopnyl human soluble tumor necrosis factor-type I receptor (PEG sTNF-RI) in subjects with active rheumatoid arthritis
    • in press
    • Martin SW, Sommers JS, Macri MJ, et al. The Pharmacokinetics of subcutaneous injections of PEGylated recombinant methiopnyl human soluble tumor necrosis factor-type I receptor (PEG sTNF-RI) in subjects with active rheumatoid arthritis. Arthritis Rheum (in press).
    • Arthritis Rheum
    • Martin, S.W.1    Sommers, J.S.2    Macri, M.J.3
  • 74
    • 0344350347 scopus 로고    scopus 로고
    • A phase 1 study of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI [p55]) in subjects with rheumatoid arthritis (RA)
    • in press
    • Caldwell JR, Davis MW, Jelaca-Maxwell K, et al. A phase 1 study of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI [p55]) in subjects with rheumatoid arthritis (RA). Arthritis Rheum (in press).
    • Arthritis Rheum
    • Caldwell, J.R.1    Davis, M.W.2    Jelaca-Maxwell, K.3


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