Development of rheumatoid arthritis is not associated with two polymorphisms in the Crohn's disease gene CARD15

Rheumatology

Volumn 42, Issue 2, 2003, Pages 304-307

  Steer, S ^c   Fisher, S A ^a   Fife, M ^c   Cuthbert, A ^a   Newton, J ^b   Wordsworth, P ^b   Lewis, C M ^a   Mathew, C G ^a   Lanchbury, J S ^c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; NUCLEASE;

ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; DNA POLYMORPHISM; GENE FREQUENCY; GENE LOCUS; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MUTATION; PRIORITY JOURNAL; REPORTER GENE; RHEUMATOID ARTHRITIS; STATISTICAL PARAMETERS;

ARTHRITIS, RHEUMATOID; CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 16; CROHN DISEASE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, GENETIC;

EID: 0344406270     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/keg091     Document Type: Article

References (34)

1. Lanchbury JS, Hall MA, Steer S. Progress and problems in defining susceptibility genes for rheumatic diseases. Rheumatology 2002;41:361-4.
2. MacGregor AJ, Snieder H, Rigby AS et al. Characterising the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum 2000;43:30-7.
3. Deighton CM, Walker DJ, Griffiths ID, Roberts DF. The contribution of HLA to rheumatoid arthritis. Clin Genet 1989;36:178-82.
4. Cornelis F, Faure S, Martinez M et al. New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci USA 1998;95:10746-50.
5. Shiozawa S, Hayashi S, Tsukamoto Y et al. Identification of the gene loci that predispose to rheumatoid arthritis. Int Immunol 1998;10:1891-5.
6. Jawaheer D, Seldin MF, Amos CI et al. A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. Am J Hum Genet 2001;68:927-36.
7. Lander ES, Schork NJ. Genetic dissection of complex traits [published erratum appears in Science 1994;266:353]. Science 1994;265:2037-48.
8. Cox A, Camp NJ, Cannings C et al. Combined sib-TDT and TDT provide evidence for linkage of the interleukin-1 gene cluster to erosive rheumatoid arthritis. Hum Mol Genet 1999;8:1707-13.
9. Fife MS, Fisher SA, John S et al. Multipoint linkage analysis of a candidate gene locus in rheumatoid arthritis demonstrates significant evidence of linkage and association with the corticotropin-releasing hormone genomic region. Arthritis Rheum 2000;43:1673-8.
10. Fife M, Steer S, Fisher S et al. Association of familial and sporadic rheumatoid arthritis with a single corticotropin-releasing hormone genomic region (8q12.3) haplotype. Arthritis Rheum 2002;46:75-82.
11. Barton A, John S, Ollier WE. Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians. Arthritis Rheum 2001;44:61-5.
12. Becker KG, Simon RM, Bailey-Wilson JE et al. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc Natl Acad Sci USA 1998;95:9979-84.
13. Myerscough A, John S, Barrett JH, Ollier WE, Worthington J. Linkage of rheumatoid arthritis to insulin-dependent diabetes mellitus loci: evidence supporting a hypothesis for the existence of common autoimmune susceptibility loci. Arthritis Rheum 2000;43:2771-5.
14. Hampe J, Cuthbert A, Croucher PJ et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001;357:1925-8.
15. Hugot JP, Chamaillard M, Zouali H et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001;411:599-603.
16. Ogura Y, Bonen DK, Inohara N et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001;411:603-6.
17. Roberts SB, MacLean CJ, Neale MC, Eaves LJ, Kendler KS. Replication of linkage studies of complex traits: an examination of variation in location estimates. Am J Hum Genet 1999;65:876-84.
18. Livak KJ, Marmaro J, Todd JA. Towards fully automated genome-wide polymorphism screening. Nat Genet 1995; 9:341-2.
19. Devlin B, Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 1995; 29:311-22.
20. Terwilliger JD, Ott J. Handbook of human genetic linkage. Baltimore (MD): Johns Hopkins University Press; 1994.
21. Cuthbert AP, Fisher SA, Mirza MM et al. The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. Gastroenterology 2002;122:867-74.
22. Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994;265:2037-48.
23. Reich DE, Goldstein DB. Detecting association in a case-control study while correcting for population stratification. Genet Epidemiol 2001;20:4-16.
24. Lesage S, Zouali H, Cezard JP et al. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet 2002;70:845-57.
25. Wise LH, Lanchbury JS, Lewis CM. Meta-analysis of genome searches. Ann Hum Genet 1999;63:263-72.
26. Gaffney PM, Kearns GM, Shark KB et al. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc Natl Acad Sci USA 1998;95:14875-9.
27. Gaffney PM, Ortmann WA, Selby SA et al. Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families. Am J Hum Genet 2000;66:547-56.
28. Shai R, Quismorio FP Jr, Li L et al. Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families. Hum Mol Genet 1999;8:639-44.
29. Nair RP, Henseler T, Jenisch S et al. Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. Hum Mol Genet 1997;6:1349-56.
30. Davies JL, Kawaguchi Y, Bennett ST et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 1994;371:130-6.
31. Brown MA, Pile KD, Kennedy LG et al. A genome-wide screen for susceptibility loci in ankylosing spondylitis. Arthritis Rheum 1998;41:588-95.
32. Miceli-Richard C, Lesage S, Rybojad M et al. CARD15 mutations in Blau syndrome. Nat Genet 2001;29:19-20.
33. Nair RP, Stuart P, Ogura Y et al. Lack of association between NOD2 3020InsC frameshift mutation and psoriasis. J Invest Dermatol 2001;117:1671-2.
34. Maini R, St Clair EW, Breedveld F et al. Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 1999; 354:1932-9.