Meta-analysis of genome searches

Annals of Human Genetics

Volumn 63, Issue 3, 1999, Pages 263-272

  Wise, L H ^a   Lanchbury, J S ^a   Lewis, C M ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOIMMUNE DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; FAMILIAL DISEASE; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENOME; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MARKER GENE; META ANALYSIS; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROBABILITY; STATISTICAL ANALYSIS;

AUTOIMMUNE DISEASES; CHROMOSOME MAPPING; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); MULTIPLE SCLEROSIS; STATISTICS;

EID: 0032822324     PISSN: 00034800     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0003480099007526     Document Type: Article

References (28)

1. ALLISON, D. B. & HEO, M. (1998). Meta-analysis of linkage data under worst-case conditions: a demonstration using the human OB region. Genetics 148, 859-865.
2. BARCELLOS, L. F., THOMSON, G., CARRINGTON. M., SCHAFER, J., BEGOVICH, A. B., LIN, P., Xu, X. H., MIN, B. Q., MARTI, D. & KLITZ, W. (1997). Chromosome 19 single-locus and multilocus haplotype associations with multiple sclerosis. Evidence of a new susceptibility locus in Caucasian and Chinese patients. JAMA 278, 1256-1261.
3. BECKER, K. G., SIMON, R. M., BAILEY-WILSON, J. E., FREIDLIN, B., BIDDISON, W. E., MCFARLAND, H. F. & TRENT, J. M. (1998). Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc. Natl. Acad. Sci. U.S.A. 95, 9979-9984.
4. BELL, J. I. & LATHROP, G. M. (1996). Multiple loci for multiple sclerosis. Nat Genet 13, 377-378.
5. CHAKRABORTY, R. STIVERS, D. N., DEKA, R., Yu, L. M., SHRIVER, M. D., FERRELL, R. E. (1996). Segregation distortion of the CTG repeats at the myotonic dystrophy locus. Am. J. Hum. Genet. 59, 209-228.
6. CHO, J. H., NICOLAE, D. L., GOLD, L. H., FIELDS, C. R., LABUDA, M. C., ROHAL, P. M., PICKLES, M. R. et al. (1998). Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1. Proc. Natl. Acad. Sc.i U.S.A. 95, 7502-7505.
7. CONCANNON, P., GOGOLIN-EWENS, K. J., HINDS, D. A., WAPELHORST, B., MORRISON, V. A., STRILING, B., MITRA, M. et al. (1998). A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nat. Genet. 19, 292-296.
8. CORNÉLIS, F., FAURE, S., MARTINEZ, M., PRUD'HOMME, J. F., FRITZ, P., DIB, C., ALVES, H., et al. (1998). New susceptibility locus for rheumatoid arthritis suggested by a genome wide linkage study. Proc. Natl. Acad. Sci. U.S.A. 95, 10746-10750.
9. DAVIES, J. L, KAWAGUCHI, Y, BENNETT, S. T COPEMAN, J. B, CORDELL, H. J, PRITCHARD, L. E, REED, P. W et al. (1994). A genome-wide search for human type I diabetes susceptibility genes. Nature 371, 130-136.
10. EBERS, G. C., KUKAY, K. BULMAN, D. E., SADOVNICK, A. D., RICE, G., ANDERSON, C., ARMSTRONG, H., et al. (1996). A full genome search in multiple sclerosis. Nat. Genet. 13, 473-476.
11. FISHER, R. A. (1932). Statistical methods for research workers. London: Oliver and Boyd.
12. GU, C., PROVINCE, M., TODOROV, A. & RAO, D. C. (1998). Meta-analysis methodology for combining non-parametric sib pair linkage results: genetic homogeneity and identical markers. Genetic Epidemiol. 15, 609-626.
13. HAINES, J. L., PERICAK-VANCE, M. A., SEBOUN, E., et al. (1996). A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. Nat. Genet. 13, 469-471.
14. HASHIMOTO, L., HABITA, C., BERESSI, J. P., DELEPINE, M., BESSE, C., CAMBON-THOMSEN, A., DESCHAMPS, I., et al. (1994). Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11q. Nature 371, 161-164.
15. HEDGES, L. V. & OLKIN, I. (1985). Statistical methods for meta-analysis. London: Academic Press.
16. HOLMANS, P. & CRADDOCK, N. (1997). Efficient strategies for genome scanning using maximum-likelihood affected-sib-pair analysis. Am. J. Hum. Genet. 60, 657-666.
17. HUGOT, J. P., LAURENT-PUIG, P., GOWER-ROUSSEAU, C., OLSON, J. M., LEE, J. C., BEAUGERIE, L., NAOM, I., et al. (1996). Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 379, 821-823.
18. KUOKKANEN, S., GSCHWEND, M., RIOUX, J. D., DALY, M. J., TERWILLIGER, J. D., TIENARI, P. J., WIKSTROM, J., et al. (1998). Genomewide scan of multiple sclerosis in Finnish multiplex families. Am. J. Hum. Gen. 61, 1379-1387.
19. LEDERMAN, W., VAJDA, S. (1985). Handbook of applicable mathematics. Vol. 5: Part B. Combinatorics and geometry. New York : John Wiley and Sons.
20. MEIN, C. A., ESPOSITO, L., DUNN, M. G., JOHNSON, G. C., TIMMS, A. E., GOY, J. Y., SMITH, A. N., et al. (1998). A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat. Genet. 19, 297-300.
21. NAIR, R. P., HENSELER, T., JENISCH, S., STUART, P., BICHAKJIAN, C. K., LENK, W., WESTPHAL, E., et al. (1997). Evidence for two psoriasis susceptibility loci HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. Hum. Mol. Genet. 6, 1349-1356.
22. OHMEN, J. D., YANG, H. Y., YAMAMOTO, K. K., ZHAO, H. Y., MA, Y., BENTLEY, L. G., HUANG, Z., ET AL. (1996). Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis. Hum. Mol. Genet. 5, 1679-1683.
23. RISCH, N. (1990). Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am. J. Hum. Genet. 46, 229-241.
24. RUBINSZTEIN, D. C. & LEGGO, J. (1997) Non-Mendelian transmission at the Machado-Joseph disease locus in normal females: preferential transmission of alleles with smaller CAG repeats. J. Med. Genet. 34, 234-236.
25. SATSANGI, J., PARKES, M., LOUIS, E., HASHIMOTO, L., KATO, N., WELSH, K., TEEWILLIGER, J. D., et al. (1996). Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat. Genet. 14, 199-202.
26. SAWCER, S., GOODFELLOW, P. N. & COMPSTON, A. (1997). The genetic analysis of multiple sclerosis. Trends Genet. 13, 234-239.
27. SAWCER, S., JONES, H. B., FEAKES, R., GRAY, J., SMALDON, N., CHATAWAY, J., ROBERTSON, N., et al. (1996). A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat. Genet. 13, 464-468.
28. TREMBATH, R. C., CLOUGH, R. L., ROSBOTHAM, J. L., JONES, A. B., CAMP, R. D., FEODSHAM, A. & BROWNE, J., et al. (1997). Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum. Mol. Genet. 6, 813-820.