Muscarinic and nicotinic cholinergic agonists: Structural analogies and discrepancies

Current Medicinal Chemistry

Volumn 10, Issue 23, 2003, Pages 2611-2620

  Bikádi, Zsolt ^a   Simonyi, Miklós ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

Acetylcholine conformation; Cholinergic agonist; Docking; Heteroatomic distances; Muscarinic selectivity; Nicotinic selectivity; Steric exclusion; Torsion angle

Indexed keywords

1,3 OXATHIOLANE DERIVATIVE; 4 AMINOBUTYRIC ACID A RECEPTOR; ACETYLCHOLINE; ACETYLCHOLINE DERIVATIVE; AMPA RECEPTOR; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; DEHYDROMUSCARINE DERIVATIVE; DIOXANE DERIVATIVE; EPIBATIDINE; G PROTEIN COUPLED RECEPTOR; GLUTAMATE RECEPTOR; GLYCINE RECEPTOR; LIGAND; MUSCARINE DERIVATIVE; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC RECEPTOR; MUSCARONE DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER; NICOTINIC AGENT; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; RHODOPSIN; SEROTONIN RECEPTOR; SULFUR DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

CALCULATION; DRUG ACTIVITY; DRUG BINDING; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; GEOMETRY; HUMAN; ISOMERISM; NONHUMAN; PHARMACOPHORE; PREDICTION; REVIEW; RIGIDITY; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINE; ANIMALS; BINDING SITES; DIOXOLANES; MODELS, MOLECULAR; MUSCARINE; MUSCARINIC AGONISTS; NICOTINE; NICOTINIC AGONISTS; RECEPTORS, MUSCARINIC; RECEPTORS, NICOTINIC; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFOXIDES;

EID: 0344393063     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033456521     Document Type: Review

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