Synthesis of a TMC-95A Ketomethylene Analogue by Cyclization via Intramolecular Suzuki Coupling

Organic Letters

Volumn 5, Issue 19, 2003, Pages 3435-3437

  Kaiser, Markus ^a   Siciliano, Carlo ^a   Assfalg Machleidt, Irmgard ^b   Groll, Michael ^a   Milbradt, Alexander G ^a   Moroder, Luis ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE DERIVATIVE; GLYCYLALANYLALANINAMIDE; KETOMETHYLENE; NUCLEOTIDE DERIVATIVE; PROTEASOME; PROTEASOME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL REACTION; CYCLIZATION; DRUG POTENCY; INHIBITION KINETICS; MOLECULAR INTERACTION; YEAST;

BICYCLO COMPOUNDS, HETEROCYCLIC; CYCLIZATION; CYSTEINE ENDOPEPTIDASES; ENZYME INHIBITORS; KINETICS; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; PEPTIDES, CYCLIC; PROTEASOME ENDOPEPTIDASE COMPLEX; STEREOISOMERISM; YEASTS;

EID: 0344392795     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol035178f     Document Type: Article

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29. (16) All compounds prepared in this study exhibited spectroscopic properties consistent with their proposed structures. Full experimental details are included in Supporting Information.