Variation of the Relaxographic "Shutter-Speed" for Transcytolemmal Water Exchange Affects the CR Bolus-Tracking Curve Shape

Magnetic Resonance in Medicine

Volumn 50, Issue 6, 2003, Pages 1151-1169

  Yankeelov, Thomas E ^a,b,d   Rooney, William D ^a,b   Li, Xin ^a,c   Springer Jr , Charles S ^a,b,c  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d VANDERBILT UNIVERSITY   (United States)

Author keywords

CR bolus tracking; Intracellular water lifetime; Shutter speed

Indexed keywords

COMPUTERIZED TOMOGRAPHY; NUCLEAR MAGNETIC RESONANCE;

ANALYTICAL THEORY; EXTRACELLULAR; INTERSTITIUM; INTRACELLULAR WATER; RELAXATION RATE CONSTANT; SHUTTER SPEED; TWO-SITE EXCHANGE PROCESS; WATER EXCHANGE;

RATE CONSTANTS;

CONTRAST MEDIUM; GADOLINIUM PENTETATE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC IMAGING; GLIOSARCOMA; KINETICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHENOTYPE; RAT; THEORY;

EID: 0344305582     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10624     Document Type: Article

References (49)

1. Caravan P, Ellison JJ, McMurry TJ, Lauffer RB. Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications. Chem Rev 1999;99:2293-2302.
2. Tofts PS. Modeling tracer kinetics in dynamic Gd-DTPA imaging. J Magn Reson Imaging 1997;7:91-101.
3. 1-weighted MRI of a diffusible tracer: standardized quantities and symbols. J Magn Reson Imaging 1999;10:223-232.
4. Brindle KM. Assessing tumor vascular function using magnetic resonance imaging. NMR Biomed 2002;15:87-88.
5. Degani H, Gusis V, Weinstein D, Fields S, Strano S. Mapping pathophysiological features of breast tumors by MRI at high spatial resolution. Nat Med 1997;3:780-782.
6. Daniel BL, Yen Y-F, Glover GH, Ikeda DM, Birdwell RL, Sawyer-Glover AM, Black JW, Plevritis SK, Jeffrey SS, Herfkens RJ. Breast disease: dynamic spiral MR imaging. Radiology 1998;209:499-509.
7. Knopp MV, Weiss E, Sinn HP, Mattern J, Junkermann H, Radeleff J, Magener A, Brix G, Delorme S, Zuna I, van Kaick G. Pathophysiologic basis of contrast enhancement in breast tumors. J Magn Reson Imaging 1999;10:260-266.
8. Harms SE. Technical report of the international working group on breast MRI. J Magn Reson Imaging 1999;10:979-1015.
9. Hayes C, Padhani AR, Leach MO. Assessing changes in tumor vascular function using dynamic contrast-enhanced magnetic resonance imaging. NMR Biomed 2002;15:154-163.
10. Reddick WE, Taylor JS, Fletcher BD. Dynamic MR imaging (DEMRI) of microcirculation in bone sarcoma. J Magn Reson Imaging 1999;10:277-285.
11. Chen W-T, Shih TT-F, Chen R-C, Lo H-Y, Chou C-T, Lee J-M, Tu H-Y. Blood perfusion of vertebral lesions evaluated with gadolinium-enhanced dynamic MRI: in comparison with compression fracture and metastasis. J Magn Reson Imaging 2002;15:308-314.
12. Rogers WJ, Kramer CM, Geskin G, Hu Y-L, Theobald TM, Vido DA, Petruolo S, Reichek N. Early contrast-enhanced MRI predicts late functional recovery after reperfused myocardial infarction. Circulation 1999;99:744-750.
13. Landis CS, Li X, Telang FW, Coderre JA, Micca PL, Rooney WD, Latour LL, Vétek G, Pályka I, Springer CS. Determination of the MRI contrast agent concentration time-course in vivo following bolus injection: effect of equilibrium transcytolemmal water exchange. Magn Reson Med 2000;44:563-574.
14. Larsson HBW, Stubgaard M, Sondergaard L, Henriksen O. In vivo quantification of the unidirectional influx constant for Gd-DTPA diffusion across the myocardial capillaries with MR imaging. J Magn Reson Imaging 1994;4:433-440.
15. Springer CS. Physicochemical principles influencing magnetopharmaceuticals. In: Gillies RJ, editor. NMR in physiology and biomedicine. Orlando: Academic Press; 1994. p 75-99.
16. Landis CS, Li X, Telang FW, Molina PE, Pályka I, Vétek G, Springer CS. Equilibrium transcytolemmal water-exchange kinetics in skeletal muscle in vivo. Magn Reson Med 1999;42:467-478.
17. Labadie C, Lee J-H, Vétek G, Springer CS. Relaxographic imaging. J Magn Reson B 1994;105:99-112.
18. Springer CS, Rooney WD, Li X. The effects of equilibrium transcytolemmal water exchange on the determination of contrast reagent concentration in vivo. Magn Reson Med 2002;47:422-424.
19. Schwarzbauer C, Morrissey SP, Deichmann R, Hillenbrand C, Syha J, Adolf H, Nöth U, Haase A. Quantitative magnetic resonance imaging of capillary water permeability and regional blood volume with an intravascular MR contrast agent. Magn Reson Med 1997;37:769-777.
20. 1-GRE blood volume measurements: implications for the evaluation of tumor angiogenesis. Magn Reson Med 2002;47:1110-1120.
21. Donahue KM, Weisskoff, RM, Burstein D. Water diffusion and exchange as they influence contrast enhancement. J Magn Reson Imaging 1997;7:102-110.
22. Barbier EL, St. Lawrence KS, Grillon E, Koretsky AP, Décorps M. A model of blood-brain-barrier permeability to water: accounting for blood inflow and longitudinal relaxation effects. Magn Reson Med 2002;47:1100-1109.
23. Parkes LM, Tofts PS. Improved accuracy of human cerebral blood perfusion measurements using arterial spin labeling: accounting for capillary water permeability. Magn Reson Med 2002;48:27-41.
24. Lee J-H, Springer CS. The effects of equilibrium exchange on diffusion-weighted NMR signals: the diffusigraphic "shutter-speed." Magn Reson Med 2003;49:450-458.
25. Yankeelov TE, Rooney WD, Springer CS. CR bolus-tracking pharmacokinetic parameters: the effects of equilibrium transcytolemmal water exchange. In: Proceedings of the 9th Annual Meeting of ISMRM, Glasgow, Scotland, 2001. p 2251.
26. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med 1994;32:66-76.
27. Landis CS, Li X, Vétek G, Springer CS. Equilibrium transcytolemmal water exchange in vivo. In: Proceedings of the 7th Annual Meeting of ISMRM, Philadelphia, 1999. p 1198.
28. Larsson HBW, Rosenbaum S, Fritz-Hansen T. Quantification of the effect of water exchange in dynamic contrast MRI perfusion measurements in the brain and heart. Magn Reson Med 2001;46:272-281.
29. Yankeelov TE, Rooney WD, Springer CS. Bolus enhanced relaxation overview, BOLERO. In: Proceedings of the 10th Annual Meeting of ISMRM, Honolulu, 2002. p 2114.
30. Lee J-H. PURR-TURBO: a novel pulse sequence for longitudinal relaxographic imaging. Magn Reson Med 2000;43:773-777.
31. o-dependence of the CR-determined exchange regime for equilibrium transcytolemmal water transport: implications for bolus-tracking studies. In: Proceedings of the 9th Annual Meeting of ISMRM, Glasgow, Scotland, 2001. p 2241.
32. Decking UKM, Pai VM, Wen H, Balaban RS. Does binding of Gd-DTPA to myocardial tissue contribute to late enhancement in a model of myocardial infarction? Magn Reson Med 2003;49:168-171,
33. Stanisz GJ, Henkelman RM. Gd-DTPA relaxivity depends on macromolecular content. Magn Reson Med 2000;44:665-667.
34. Yankeelov TE. The effects of equilibrium transcytolemmal water exchange on magnetic resonance imaging measurement of contrast reagent pharmacokinetics. Ph.D. dissertation, State University of New York, Stony Brook, New York, 2003. p 52,53,75-82.
35. Port RE, Knopp, MV, Brix G, Dynamic contrast-enhanced MRI using Gd-DTPA: interindividual variability of the arterial input function and consequences for the assessment of kinetics in tumors. Magn Reson Med 2001;45:1030-1038.
36. Lee J-H, Li X, Sammi MK, Springer CS. Using flow relaxography to elucidate flow relaxivity. J Magn Reson 1999;136:102-113.
37. Rooney WD, Telang FW, Springer CS. Quantitative 4T determination of normal human brain vascular properties suggests CR transport across BBB. In: Proceedings of the 10th Annual Meeting of ISMRM, Honolulu, 2002. p 1314.
38. Yankeelov TE, Rooney WD, Springer CS. Field-dependence of the hyperfine BALD (blood agent level dependent) effect: equilibrium transendothelial water exchange. In: Proceedings of the 10th Annual Meeting of ISMRM, Honolulu, 2002. p 1091.
39. Perkiö J, Aronen HJ, Kangasmäki A, Liu Y, Karonen J, Savolainen S, Østergaard L. Evaluation of four postprocessing methods for determination of cerebral blood volume and mean transit time by dynamic susceptibility contrast imaging. Magn Reson Med 2002;47:973-981.
40. Sammi MK. Some quantification issues in medical imaging. Ph.D. dissertation, State University of New York, Stony Brook, New York, 1999. p 44-85.
41. Padhani AR, Hayes C, Landau S, Leach MO. Reproducibility of quantitative dynamic MRI of normal human tissues. NMR Biomed 2002;15:143-153.
42. Calbraith SM, Lodge MA, Taylor NJ, Rustin CJS, Bentzen S, Stirling JJ, Padhani AR. Reproducibility of dynamic contrast-enhanced MRI in human muscle and tumors: comparison of quantitative and semi-quantitative analysis. NMR Biomed 2002;15:132-142.
43. Maxwell RJ, Wilson J, Prise VE, Vojnovic B, Rustin CJ, Lodge MA, Tozer GM. Evaluation of the anti-vascular effects of combretastatin in rodent tumors by dynamic contrast enhanced MRI. NMR Biomed 2002;15:89-98.
44. Fu D, Libson A, Miercke JW, Wietzman C, Nollert P, Krucinski J, Stroud RM. Structure of a glycerol-conducting channel and the basis for its selectivity. Science 2000;290:481-486.
45. Nagelhus EA, Veruki ML, Torp R, Haug F-M, Laake JH, Nielsen S, Agre P, Ottersen OP. Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Müller cells and fibrous astrocytes. J Neurosci 1998;18:2506-2519.
46. 1H NMR experiments during cerebral ischemia: influence of intracellular restrictions, extracellular tortuosity, and exchange. Magn Reson Imaging 1998;16:1023-1032.
47. Yankeelov TE, Rooney WD, Springer CS. High-field allows low CR dose advantages. In: Proceedings of the 10th Annual Meeting of ISMRM, Honolulu, 2002. p 2117.
48. Yankeelov TE, Springer CS. Factoring the permeability and perfusion contributions to CR bolus-tracking pharmacokinetics. In: Proceedings of the 9th Annual Meeting of ISMRM, Glasgow, Scotland, 2001. p 628.
49. Lyng H, Dahle GA, Kaalhus O, Skretting A, Rofstad EK. Measurement of perfusion rate in human melanoma xenografts by contrast-enhanced magnetic resonance imaging. Magn Reson Med 1998;40:89-98.