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Volumn 18, Issue 11, 1998, Pages 4001-4007

Pore mutation in a G-protein-gated inwardly rectifying K+ channel subunit causes loss of K+-dependent inhibition in weaver hippocampus

Author keywords

Adenosine; G protein activated potassium currents; GABA(B) receptors; GIRK2; Hippocampus; Kir3.2; R baclofen; Serotonin; Slow IPSPs; Weaver

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BACLOFEN; GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 0344074645     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-11-04001.1998     Document Type: Article
Times cited : (27)

References (48)
  • 1
    • 0023470549 scopus 로고
    • Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro
    • Andrade R, Nicoll RA (1987) Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro. J Physiol (Lond) 394:99-124.
    • (1987) J Physiol (Lond) , vol.394 , pp. 99-124
    • Andrade, R.1    Nicoll, R.A.2
  • 3
    • 0024508323 scopus 로고
    • Tonic/clonic seizures in a mouse mutant carrying the weaver gene
    • Eisenberg B, Messer A (1989) Tonic/clonic seizures in a mouse mutant carrying the weaver gene. Neurosci Lett 96:168-172.
    • (1989) Neurosci Lett , vol.96 , pp. 168-172
    • Eisenberg, B.1    Messer, A.2
  • 5
    • 0028795931 scopus 로고
    • B-mediated inhibitions in the CA3 hippocampal region of the rat
    • B-mediated inhibitions in the CA3 hippocampal region of the rat. J Neurophysiol 73:246-255.
    • (1995) J Neurophysiol , vol.73 , pp. 246-255
    • Gaiarsa, J.-L.1    Tseeb, V.2    Ben-Ari, Y.3
  • 6
    • 0020461795 scopus 로고
    • Granule cell as a site of gene action in the weaver mouse cerebellum: Evidence from heterozygous mutant chimeras
    • Goldowitz D, Mullen RJ (1982) Granule cell as a site of gene action in the weaver mouse cerebellum: evidence from heterozygous mutant chimeras. J Neurosci 10:720-722.
    • (1982) J Neurosci , vol.10 , pp. 720-722
    • Goldowitz, D.1    Mullen, R.J.2
  • 7
    • 0029391467 scopus 로고
    • Tune into the weaver channel
    • Goldowitz D, Smeyne RJ (1995) Tune into the weaver channel. Nat Genet 11:107-109.
    • (1995) Nat Genet , vol.11 , pp. 107-109
    • Goldowitz, D.1    Smeyne, R.J.2
  • 8
    • 0025903392 scopus 로고
    • The electrophysiology of adenosine in the mammalian central nervous system
    • Greene RW, Haas HL (1991) The electrophysiology of adenosine in the mammalian central nervous system. Prog Neurobiol 36:329-341.
    • (1991) Prog Neurobiol , vol.36 , pp. 329-341
    • Greene, R.W.1    Haas, H.L.2
  • 9
    • 0021331375 scopus 로고
    • Defects in specific associations between astroglia and neurons occur in microcultures of weaver mouse cerebellar cells
    • Hatten ME, Liem RK, Mason CA (1984) Defects in specific associations between astroglia and neurons occur in microcultures of weaver mouse cerebellar cells. J Neurosci 4:1163-1172.
    • (1984) J Neurosci , vol.4 , pp. 1163-1172
    • Hatten, M.E.1    Liem, R.K.2    Mason, C.A.3
  • 10
    • 0026577757 scopus 로고
    • Quantal analysis of suppressing action of baclofen on mossy fiber synapses in guinea pig hippocampus
    • Hirata K, Sawada S, Yamamoto C (1992) Quantal analysis of suppressing action of baclofen on mossy fiber synapses in guinea pig hippocampus. Brain Res 578:33-40.
    • (1992) Brain Res , vol.578 , pp. 33-40
    • Hirata, K.1    Sawada, S.2    Yamamoto, C.3
  • 11
    • 0027787702 scopus 로고
    • B currents in granule cells of the guinea-pig hippocampus
    • B currents in granule cells of the guinea-pig hippocampus. Pflügers Arch 425:491-498.
    • (1993) Pflügers Arch , vol.425 , pp. 491-498
    • Jarolimek, W.1    Misgeld, U.2
  • 12
    • 0027336798 scopus 로고
    • CGP 55845A blocks baclofen, γ-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons
    • Jarolimek W, Demmelhuber J, Bijak M, Misgeld U (1993) CGP 55845A blocks baclofen, γ-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons. Neurosci Lett 154:31-34.
    • (1993) Neurosci Lett , vol.154 , pp. 31-34
    • Jarolimek, W.1    Demmelhuber, J.2    Bijak, M.3    Misgeld, U.4
  • 13
    • 0028036756 scopus 로고
    • Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro
    • Jarolimek W, Bijak M, Misgeld U (1994) Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro. Synapse 18:169-177.
    • (1994) Synapse , vol.18 , pp. 169-177
    • Jarolimek, W.1    Bijak, M.2    Misgeld, U.3
  • 18
    • 0342806880 scopus 로고    scopus 로고
    • + channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain
    • + channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain. J Neurosci 16:7137-7150.
    • (1996) J Neurosci , vol.16 , pp. 7137-7150
    • Liao, Y.J.1    Jan, Y.N.2    Jan, L.Y.3
  • 19
    • 0039357820 scopus 로고    scopus 로고
    • + channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons
    • + channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 19:687-695.
    • (1997) Neuron , vol.19 , pp. 687-695
    • Lüscher, C.1    Jan, L.Y.2    Stoffel, M.3    Malenka, R.C.4    Nicoll, R.A.5
  • 20
    • 0018730118 scopus 로고
    • Heterosynaptic postactivation potentiation in hippocampal CA3 neurons: Long-term changes of the postsynaptic potentials
    • Misgeld U, Sarvey JM, Klee MR (1979) Heterosynaptic postactivation potentiation in hippocampal CA3 neurons: long-term changes of the postsynaptic potentials. Exp Brain Res 37:217-229.
    • (1979) Exp Brain Res , vol.37 , pp. 217-229
    • Misgeld, U.1    Sarvey, J.M.2    Klee, M.R.3
  • 21
    • 0026442817 scopus 로고
    • K-dependent inhibition in the dentate-CA3 network of guinea pig hippocampal slices
    • Misgeld U, Bijak M, Brunner H, Dembowsky K (1992) K-dependent inhibition in the dentate-CA3 network of guinea pig hippocampal slices. J Neurophysiol 68:1548-1557.
    • (1992) J Neurophysiol , vol.68 , pp. 1548-1557
    • Misgeld, U.1    Bijak, M.2    Brunner, H.3    Dembowsky, K.4
  • 22
    • 0028983775 scopus 로고
    • B receptors and the effects of baclofen in the mammalian central nervous system
    • B receptors and the effects of baclofen in the mammalian central nervous system. Prog Neurobiol 46:423-462.
    • (1995) Prog Neurobiol , vol.46 , pp. 423-462
    • Misgeld, U.1    Bijak, M.2    Jarolimek, W.3
  • 23
    • 0025360429 scopus 로고
    • Inhibitory role of dentate hilus neurons in guinea pig hippocampal slice
    • Müller W, Misgeld U (1990) Inhibitory role of dentate hilus neurons in guinea pig hippocampal slice. J Neurophysiol 64:46-56.
    • (1990) J Neurophysiol , vol.64 , pp. 46-56
    • Müller, W.1    Misgeld, U.2
  • 24
    • 0030861479 scopus 로고    scopus 로고
    • An immunocytochemical study on the distribution of two G protein gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain
    • Murer G, Adelbrecht C, Lauritzen I, Lesage F, Lazdunski M, Agid Y, Raismanvozari R (1997) An immunocytochemical study on the distribution of two G protein gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain. Neuroscience 80:345-357.
    • (1997) Neuroscience , vol.80 , pp. 345-357
    • Murer, G.1    Adelbrecht, C.2    Lauritzen, I.3    Lesage, F.4    Lazdunski, M.5    Agid, Y.6    Raismanvozari, R.7
  • 26
    • 0023804944 scopus 로고
    • The coupling of neurotransmitter receptors to ion channels in the brain
    • Nicoll RA (1988) The coupling of neurotransmitter receptors to ion channels in the brain. Science 241:545-551.
    • (1988) Science , vol.241 , pp. 545-551
    • Nicoll, R.A.1
  • 27
    • 0029115971 scopus 로고
    • A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation
    • Patil N, Cox DR, Bhat D, Faham M, Myers RM, Peterson AS (1995) A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nat Genet 11:126-129.
    • (1995) Nat Genet , vol.11 , pp. 126-129
    • Patil, N.1    Cox, D.R.2    Bhat, D.3    Faham, M.4    Myers, R.M.5    Peterson, A.S.6
  • 28
    • 0015749644 scopus 로고
    • Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mouse
    • Rakic P, Sidman RL (1973a) Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mouse. J Comp Neurol 152:103-132.
    • (1973) J Comp Neurol , vol.152 , pp. 103-132
    • Rakic, P.1    Sidman, R.L.2
  • 29
    • 0015719472 scopus 로고
    • Organisation of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice
    • Rakic P, Sidman RL (1973b) Organisation of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice. J Comp Neurol 152:133-162.
    • (1973) J Comp Neurol , vol.152 , pp. 133-162
    • Rakic, P.1    Sidman, R.L.2
  • 30
    • 0021245295 scopus 로고
    • Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and non-limbic striatum
    • Roffler-Tarlov S, Graybiel AM (1984) Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and non-limbic striatum. Nature 307:62-66.
    • (1984) Nature , vol.307 , pp. 62-66
    • Roffler-Tarlov, S.1    Graybiel, A.M.2
  • 31
    • 0027140282 scopus 로고
    • Presynaptic inhibition of excitatory synaptic transmission mediated by α adrenergic receptors in area CA3 of the rat hippocampus in vitro
    • Scanziani M, Gähwiler BH, Thompson SM (1993) Presynaptic inhibition of excitatory synaptic transmission mediated by α adrenergic receptors in area CA3 of the rat hippocampus in vitro. J Neurosci 13:5393-5401.
    • (1993) J Neurosci , vol.13 , pp. 5393-5401
    • Scanziani, M.1    Gähwiler, B.H.2    Thompson, S.M.3
  • 33
    • 0025062586 scopus 로고
    • A subset of local interneurons generate slow inhibitory postsynaptic potentials in hippocampal neurons
    • Segal M (1990) A subset of local interneurons generate slow inhibitory postsynaptic potentials in hippocampal neurons. Brain Res 511:163-164.
    • (1990) Brain Res , vol.511 , pp. 163-164
    • Segal, M.1
  • 36
    • 0030448948 scopus 로고    scopus 로고
    • A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation
    • Silverman SK, Kofuji P, Dougherty DA, Davidson N, Lester HA (1996) A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation. Proc Natl Acad Sci USA 93:15429-15434.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15429-15434
    • Silverman, S.K.1    Kofuji, P.2    Dougherty, D.A.3    Davidson, N.4    Lester, H.A.5
  • 39
    • 0024355065 scopus 로고
    • Development and death of external granule cell layer in the weaver mouse cerebellum: A quantitative study
    • Smeyne RJ, Golduwitz D (1989) Development and death of external granule cell layer in the weaver mouse cerebellum: a quantitative study. J Neurosci 9:1608-1620.
    • (1989) J Neurosci , vol.9 , pp. 1608-1620
    • Smeyne, R.J.1    Golduwitz, D.2
  • 40
    • 0029662055 scopus 로고    scopus 로고
    • B, receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons
    • B, receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons. J Nuurosci 16:6374-6385.
    • (1996) J Nuurosci , vol.16 , pp. 6374-6385
    • Sodickson, D.L.1    Bean, B.P.2
  • 41
    • 0026611390 scopus 로고
    • B-mediated responses in the CA1 region of the rat hippocampal slice
    • B-mediated responses in the CA1 region of the rat hippocampal slice, J Neurosci 12:3466-3472.
    • (1992) J Neurosci , vol.12 , pp. 3466-3472
    • Solís, J.M.1    Nicoll, R.A.2
  • 43
    • 0022498069 scopus 로고
    • Baclofen suppresses hippocampal epileptiform activity at low concentrations without suppressing synaptic transmission
    • Swartzwelder HS, Bragdon AC, Sutch CP, Ault B, Wilson WA (1986) Baclofen suppresses hippocampal epileptiform activity at low concentrations without suppressing synaptic transmission. J Pharmacol Exp Ther 237:881-887.
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 881-887
    • Swartzwelder, H.S.1    Bragdon, A.C.2    Sutch, C.P.3    Ault, B.4    Wilson, W.A.5
  • 44
    • 0030586384 scopus 로고    scopus 로고
    • The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GJRK2
    • Tong YH, Wei JJ, Zhang SW, Strong JA, Dlouhy SR, Hodes ME, Ghetti B, Yu L (1996) The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GJRK2. FEBS Lett 390:63-68.
    • (1996) FEBS Lett , vol.390 , pp. 63-68
    • Tong, Y.H.1    Wei, J.J.2    Zhang, S.W.3    Strong, J.A.4    Dlouhy, S.R.5    Hodes, M.E.6    Ghetti, B.7    Yu, L.8
  • 45
    • 0023944083 scopus 로고
    • Mesencephalic dopamine cell deficít involves areas A8, A9, and A10 in weaver mutant mice
    • Triarhou LC, Norton J, Ghetti B (1988) Mesencephalic dopamine cell deficít involves areas A8, A9, and A10 in weaver mutant mice. Exp Brain Res 70:256-265.
    • (1988) Exp Brain Res , vol.70 , pp. 256-265
    • Triarhou, L.C.1    Norton, J.2    Ghetti, B.3


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