Complement and complement deficiencies

Seminars in Liver Disease

Volumn 17, Issue 4, 1997, Pages 297-310

  Whaley, Keith ^a   Schwaeble, Wilhelm ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Biosynthesis; Complement; Deficiencies; Immunity; Liver

Indexed keywords

ANAPHYLATOXIN; COMPLEMENT; COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT RECEPTOR; LECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 3; REGULATOR PROTEIN;

ANTIGEN ANTIBODY COMPLEX; CHEMOTAXIS; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT DEFICIENCY; CYTOLYSIS; HUMAN; IMMUNE RESPONSE; MONOCYTE; MULTIGENE FAMILY; NEUTROPHIL; OPSONIZATION; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0030679662     PISSN: 02728087     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1007206     Document Type: Review

References (40)

1. Law A, Reid KBM. Complement. Oxford, IRL Press, 1994
2. Weiler JM. Introduction to complement, in: Whaley K, Loos M, Weiler JM (eds): Complement in Health and Disease, ed. Z. Dordrecht, Kluwer Academic, 1993, pp 1-35
3. Goldberger G, Colton HR. Precursor complement protein (pro-C4) is converted in vitro to native C4 by plasmin. Nature 286:515-516, 1980
4. Ikeda K, Sannoh T, Kawasaki N, et al: Serum lectin with known structure activates complement through the classical pathway. J Biol Chem 262:7541-7544, 1987
5. Lu J, Thiel S, Wiedemann H, et al: Binding of the pentamer/ hexamer forms of mannan-binding protein to zymosan activates the proenzyme Clr2Cls2 complex, of the classical pathway of complement without involvement of Clq. J Immunol 144:2287, 1990
6. Lu J, Sim RB. Collectins and collectin receptors, in Erdei A (ed): New Aspects of Complement Structure and Function. Austin, TX, R.G. Landes Co., 1994, pp 85-106
7. Matsushita M, Fujita T. Activation of the classical complement pathway by mannose-binding protein in association with a novel Cls-like protease J Exp Med 176:1497-1502, 1992
8. Matsushita M, Fujita T. Cleavage of the third component of complement (C3) by mannose-binding protein-associated serine protease (MASP) with subsequent complement activation. Immunobiology 194:443-448, 1995
9. Jensen TV, Stover C, Poulsen K, et al: Cloning of cDNA encoding a human MASP-like protein (MASP-2). Mol Immunol 33(suppl 1):81 (abstract), 1996
10. Whaley K. Biosynthesis of complement in monocytes. J Exp Med 151:501-516, 1980
11. Schwaeble W, Dippold W, Schäfer MK-H, et al. Properdin, a positive regulator of complement activation, is expressed in human T-cell lines and peripheral blood T-cells. J Immunol 151: 2521-2528, 1993
12. Schwaeble W, Huemer HP, Möst, J, et al. Expression of properdin in human monocytes. Eur J Biochem 219:759-764, 1994
13. Farries TC, Atkinson JP. Biosynthesis of properdin. J Immunol 142:842-846, 1989
14. Wirthmüller U, Dewald B, Thelen M, et al. Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils. J Immunol 158:4444-4451, 1997
15. Whaley K, Ruddy S. Modulation of the alternative complement pathway by B1H globin. J Exp Med 144:1147-1163, 1976
16. Whaley K, Ruddy S. Modulation of C3b hemolytic activity by a plasma protein distinct from C3b inactivator. Science 193: 1011-1013, 1976
17. Schwaeble W, Zwirner J, Schulz TF, et al. Human complement factor H: Expression of an additional truncated gene product of 43-kDa in human liver. Eur J Immunol 17:1485-1489, 1987
18. Misasi R, Huemer HP, Schwaeble W, et al. Human complement factor H: An additional gene product of 43kDa isolated from human plasma shows cofactor activity for the cleavage of the third component of complement. Eur J Immunol 19:1765-1768, 1989
19. Melchers F, Erdei A, Schulz T, et al. Growth control of activated, synchronized murine B cells by the C3d fragment of human complement. Nature 317:264-267, 1985
20. Tenner A. C1q interaction with cell surface receptors. Behring Inst Mitt 84:220, 1989
21. Malhotra R, Thiel S, Reid KBM, et al. Human leucocyte C1q receptor binds to other soluble proteins with collagen domains. J Exp Med 173:955-959, 1990
22. McCauliffe DP, Lux FA, Lieu TS, et al. Molecular cloning, expression, and chromosome 19 localisation of a human Ro/SS-A autoantigen. J Clin Invest 85:1379-1382, 1990
23. Michalck M, Milner RE, Burns K, et al. Calreticulin. Biochem J 285:681-693, 1992
24. Ruiz S, Tenner AJ. C1q and pulmonary surfactant protein A (SPA) trigger enhanced phagocytic capacity with identical kinetics and via the same 126,000 Mr cell surface receptor. Mol Immunol, 33(suppl 1):65 (abstract), 1996
25. Nepomuceno RR, Tenner A-J. mRNA and cell surface protein expression of the human C1q receptor that enhances phagocytosis is detected in cells of myeloid but not lymphoid lineage. Mol Immunol 33(suppl 1):65 (abstract), 1996
26. Ghebrehiwet B, Lim B-L, Peerschke EIB, et al. Isolation, cDNA cloning, and overexpression of a 33 kDa cell surface glycoprotein that binds to the globular "heads" of of C1q. J Exp Med 179:1809-1821, 1994
27. van den Berg RH, Faber-Krol MC, vas Es LA, et al. Intracellular localisation of globular C1q receptors in mesangial cells and Raji. Mol Immunol 33(suppl 1):21 (abstract), 1996
28. Rosen FS. Genetic deficiencies of the complement system: An overview, in Whaley K, Loos M, Weiler JM (eds): Complement in Health and Disease, ed 2. Dordrecht, Kluwer Academic, 1993, pp 159-197
29. Reid KBM, Thompson RA. Characterisation of a non-functional form of C1q found in patients with a genetically linked deficiency of C1q activity. Mol Immunol 20:1117-1125, 1983
30. Stoppa-Lyonnet D, Carter PE, Meo T, et al. Clusters of intragenic Alu repeats predispose the human C1 inhibitor locus to deleterious rearrangements. Proc Natl Acad Sci USA 87:1551-1555, 1990
31. Tosi M. Molecular genetics of C1-inhibitor and hereditary angio-oedema, in Whaley K, Loos M, Weiler JM (eds): Complement in Health and Disease, ed 2 Dordrecht, Kluwer Academic, 1993, pp 245-267
32. Dunham I, Sargent CA, Trowsdale J, et al. Molecular mapping of the human major histocompatibility complex by pulsed-field gel electrophoresis. Proc Natl Acad Sci USA 84:7237-7241, 1987
33. Colten HR, Strunk RC. Synthesis of complement in liver and at extra hepatic sites, in Whaley K, Loos M, Weiler JM (eds): Complement in Health and Disease, ed 2. Dordrecht, Kluwer Academic, 1993, pp 127-158
34. Dietzschold B, Schwaeble W, Schäfer MK-H, et al. The expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis. J Neurol Sci 130:11-16, 1995
35. Schwaeble W, Schäfer MK-H, Petry F, et al. Follicular dendritic, interdigitating cells and cells of the monocyte-macrophage lineage are the C1q-producing sources in rat spleen: Identification of specific cell types by in situ hybridization and immunohistochemical analysis. J Immunol 155:4971-4978, 1995
36. De Ceulaer C, Papazoglou S, Whaley K. Increased biosynthesis of complement components by cultured monocytes, synovial fluid macrophages and synovial membrane cells from patients with rheumatoid arthritis. Immunology 41:37-43, 1980.
37. Sellar GC, Blake DJ, Reid KBM. Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. Biochem J 274:481-487, 1991
38. Reid KBM, Day AJ. Structure-function relationships of the complement components. Immunol Today 10:177, 1989
39. Goundis D, Reid KBM. Properdin, the terminal complement components, thrombospondin and the circumsporozoite protein of malaria parasites contain similar sequence motifs. Nature 335: 82-86, 1988
40. Holmskov U, Malhotra R, Sim RB, et al. Collectins, collagenous C-type lectins of the immune defense system. Immunol Today 15:67-70, 1994