The full length HLA-G1 and no other alternative form of HLA-G is expressed at the cell surface of transfected cells

Human Immunology

Volumn 61, Issue 3, 2000, Pages 212-224

  Mallet, Valérie ^a   Pröll, Johannes ^a   Solier, Corinne ^a   Aguerre Girr, Maryse ^a   Derossi, Marco ^a   Loke, Yung Wai ^b   Lenfant, Françoise ^a   Le Bouteiller, Philippe ^a  

^a INSERM   (France)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Enhanced green fluorescent protein; HLA G; Soluble HLA; Splice variants; Trophoblast

Indexed keywords

GREEN FLUORESCENT PROTEIN; HLA G ANTIGEN; MONOCLONAL ANTIBODY; RHODAMINE;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL SURFACE; CONFOCAL MICROSCOPY; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT; ENDOPLASMIC RETICULUM; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MEMBRANE PROTEINS; MICE; PROTEIN BIOSYNTHESIS; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0343340052     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(99)00166-4     Document Type: Article

References (57)

1. Le Bouteiller P., Blaschitz A. The functionality of HLA-G is emerging. Immunol Rev. 167:1999;233.
2. Le Bouteiller P. HLA class I chromosomal region, genes, and products facts and questions . Crit Rev Immunol. 14:1994;89.
3. Gobin S., van den Elsen P. The regulation of HLA class I expression is HLA-G the odd one out? Seminars in Cancer Biology. 9:1999;55.
4. Moreau P., Lefebvre S., Gourand L., Dausset J., Carosella E.D., Paul P. Specific binding of nuclear factors to the HLA-G gene promoter correlates with a lack of HLA-G transcripts in first trimester human fetal liver. Hum Immunol. 59:1998;751.
5. Geraghty D.E., Koller B.H., Orr H.T. A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. Proc Natl Acad Sci USA. 84:1987;9145.
6. Ishitani A., Geraghty D.E. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens. Proc Natl Acad Sci USA. 89:1992;3947.
7. Fujii T., Ishitani A., Geraghty D.E. A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4. J Immunol. 153:1994;5516.
8. Moreau P., Carosella E., Teyssier M., Prost S., Gluckman E., Dausset J., Kirszenbaum M. Soluble HLA-G molecule. An alternatively spliced HLA-G mRNA form candidate to encode it in peripheral blood mononuclear cells and human trophoblasts. Hum Immunol. 43:1995;231.
9. Wei X.H., Orr H.T. Differential expression of HLA-E, HLA-F, and HLA-G transcripts in human tissue. Hum Immunol. 29:1990;131.
10. Amiot L., Onno M., Drénou B., Monvoisin C., Fauchet R. HLA-G class I gene expression in normal and malignant hematopoietic cells. Hum Immunol. 59:1998;524.
11. Chu W., Fant M.E., Geraghty D.E., Hunt J.S. Soluble HLA-G in human placentas synthesis in trophoblasts and interferon-gamma-activated macrophages but not placental fibroblasts . Hum Immunol. 59:1998;435.
12. Hiby S.E., King A., Sharkey A., Loke Y.W. Molecular studies of trophoblast HLA-G polymorphism, isoforms, imprinting and expression in preimplantation embryo . Tissue Antigens. 53:1999;1.
13. Puppo F., Costa M., Contini P., Brenci S., Cevasco E., Ghio M., Norelli R., Bensussan A., Capitano G., Indiveri F. Determination of soluble HLA-G and HLA-A, -B, and -C molecules in pregnancy. Transplantation Proceedings. 31:1999;1841.
14. Fournel S., Aguerre-Girr M., Campan A., Salauze L., Berrebi A., Lone Y., Lenfant F., Le Bouteiller P. Soluble HLA-G purification from eucaryotic transfected cells and detection by a specific ELISA . Am J Reprod Immunol. 42:1999;22.
15. Rebmann V., Pfeiffer K., Passler M., Ferrone S., Maier S., Weiss E., Grosse-Wilde H. Detection of soluble HLA-G molecules in plasma and amniotic fluid. Tissue Antigens. 53:1999;14.
16. Crisa L., McMaster M.T., Ishii J.K., Fisher S.J., Salomon D.R. Identification of a thymic epithelial cell subset sharing expression of the class Ib HLA-G molecule with fetal trophoblasts. J Exp Med. 186:1997;289.
17. Mallet V., Blaschitz A., Crisa L., Schmitt C., Fournel S., King A., Loke Y., Dohr G., Le Bouteiller P. HLA-G in human thymus a subpopulation of medullary epithelial but not CD83+ dendritic cells expresses HLA-G as a membrane bound and soluble protein . Int Immunol. 11:1999;889.
18. Kalejta R.F., Shenk T., Beavis A.J. Use of a membrane-localized green fluorescent protein allows simultaneous identification of transfected cells and cell cycle analysis by flow cytometry. Cytometry. 29:1997;286.
19. Naramura M., Hu R., Gu H. Mice with a fluorescent marker for interleukin 2 gene activation. Immunity. 9:1998;209.
20. Hadjantonakis A., Gertsenstein M., Ikawa M., Okabe M., Nagy A. Generating green fluorescent mice by germline transmission of green fluorescent ES cells. Mech Dev. 76:1998;79.
21. Kavathas P., Herzenberg L.A. Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin selection by fluorescence-activated cell sorting . Proc Natl Acad Sci USA. 80:1983;524.
22. Sernee M.F., Ploegh H.L., Schust D.J. Why certain antibodies cross-react with HLA-A and HLA-G epitope mapping of two common MHC class I reagents . Mol Immunol. 35:1998;177.
23. Boucraut J., Guillaudeux T., Alizadeh M., Boretto J., Chimini G., Malecaze F., Semana G., Fauchet R., Pontarotti P., Le Bouteiller P. HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR. Immunogenetics. 38:1993;117.
24. Sambrook J., Fritsh E.F., Maniatis T. Transfection of Co-precipitates of Calcium Phosphate and DNA, p16.30-16.36. Molecular Cloning A Laboratory Manual . 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
25. Guillaudeux T., Rodriguez A.M., Girr M., Mallet V., Ellis S.A., Sargent I.L., Fauchet R., Alsat E., Le Bouteiller P. Methylation status and transcriptional expression of the MHC class I loci in human trophoblast cells from term placenta. J Immunol. 154:1995;3283.
26. Dezz Ropp J., Donahue C., Wolfgang-Kimball D., Hooley J., Chin J., Hoffman R., Cuthbertson R., Bauer K. Aequorea green fluorescent protein analysis by flow cytometry. Cytometry. 21:1995;309.
27. Lenfant F., Fort M., Rodriguez A.M., Campan A., Aguerre-Girr M., Sommer E., Abbal M., Ohayon E., Le Bouteiller P. Absence of imprinting of HLA class Ia genes leads to co-expression of biparental alleles on term human trophoblast cells upon IFN-gamma induction. Immunogenetics. 47:1998;297.
28. Barnstable C.J., Bodmer W.F., Brown G., Galfre G., Milstein C., Williams A.F., Ziegler A. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell. 14:1978;9.
29. Rodriguez A.M., Mallet V., Lenfant F., Arnaud J., Girr M., Urlinger S., Bensussan A., Le Bouteiller P. Interferon-gamma rescues HLA class Ia cell surface expression in term villous trophoblast cells by inducing synthesis of TAP proteins. Eur J Immunol. 27:1997;45.
30. Lemonnier F.A., Le Bouteiller P.P., Olive D., Malissen B., Mishal Z., Layet C., Dubreuil J., Caillol D.H., Kourilsky F.M., Jordan B.R. Transformation of LMTK-cells with purified class I genes. V. Antibody-induced structural modification of HLA class I molecules results in potentiation of the fixation of a second monoclonal antibody. J Immunol. 132:1984;1176.
31. Genestier L., Paillot R., Bonnefoy-Berard N., Meffre G., Flacher M., Fevre D., Liu Y.J., Le Bouteiller P., Waldmann H., Engelhard V.H., Banchereau J., Revillard J.P. Fas-independent apoptosis of activated T cells induced by antibodies to the HLA class I alpha 1 domain. Blood. 90:1997;3629.
32. Stam N.J., Vroom T.M., Peters P.J., Pastoors E.B., Ploegh H.L. HLA-A and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, parrafin-embedded tissue sections and in cryo-immuno-electron microscopy. Int Immunol. 2:1990;113.
33. Lee N., Malacko A.R., Ishitani A., Chen M.C., Bajorath J., Marquardt H., Geraghty D.E. The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association. Immunity. 3:1995;591.
34. Loke Y.W., King A., Burrows T., Gardner L., Bowen M., Hiby S., Howlett S., Holmes N., Jacobs D. Evaluation of trophoblast HLA-G antigen with a specific monoclonal antibody. Tissue Antigens. 50:1997;135.
35. Blaschitz A., Lenfant F., Mallet V., Hartmann M., Bensussan A., Geraghty D.E., Le Bouteiller P., Dohr G. Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA-G. Eur J Immunol. 27:1997;3380.
36. Rajagopalan S., Brenner M.B. Calnexin retains unassembled major histocompatibility complex class I free heavy chains in the endoplasmic reticulum. J Exp Med. 180:1994;407.
37. Chatterjee S., Stochaj U. Monitoring nuclear transport in HeLa cells using the green fluorescent protein. Biotechniques. 21:1996;62.
38. Yang Y., Chu W., Geraghty D.E., Hunt J.S. Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-gamma. J Immunol. 156:1996;4224.
39. Koopmann J.O., Hammerling G.J., Momburg F. Generation, intracellular transport and loading of peptides associated with MHC class I molecules. Curr Opin Immunol. 9:1997;80.
40. Brodsky F.M., Lem L., Bresnahan P.A. Antigen processing and presentation. Tissue Antigens. 47:1996;464.
41. Sadasivan B., Lehner P.J., Ortmann B., Spies T., Cresswell P. Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP. Immunity. 5:1996;103.
42. Harris M.R., Yu Y.Y., Kindle C.S., Hansen T.H., Solheim J.C. Calreticulin and calnexin interact with different protein and glycan determinants during the assembly of MHC class I. J Immunol. 160:1998;5404.
43. Wainwright S.D., Simpson K.L., Holmes C.H. Calreticulin associates with non-HLA-A,-B class I proteins in the human choriocarcinoma cell lines JEG-3 and BeWo. Immunology. 93:1998;437.
44. Carreno B.M., Solheim J.C., Harris M., Stroynowski I., Connolly J.M., Hansen T.H. TAP associates with a unique class I conformation, whereas calnexin associates with multiple class I forms in mouse and man. J Immunol. 155:1995;4726.
45. Schust D.J., Hill A.B., Ploegh H.L. Herpes simplex virus blocks intracellular transport of HLA-G in placentally derived human cells. J Immunol. 157:1996;3375.
46. Suh W.K., Derby M.A., Cohen-Doyle M.F., Schoenhals G.J., Fruh K., Berzofsky J.A., Williams D.B. Interaction of murine MHC class I molecules with tapasin and TAP enhances peptide loading and involves the heavy chain alpha3 domain. J Immunol. 162:1999;1530.
47. Seitz C., Uchanska-Ziegler B., Zank A., Ziegler A. The monoclonal antibody HCA2 recognises a broadly shared epitope on selected classical as well as several non-classical HLA class I molecules. Mol Immunol. 35:1998;819.
48. Bjorkman P.J., Saper M.A., Samraoui B., Bennett W.S., Strominger J.L., Wiley D.C. Structure of the human class I histocompatibility antigen, HLA-A2. Nature. 329:1987;506.
49. Ferrier P., Kahn-Perles B., Layet C., Pontarotti P., Sire J., Hakem R., Le Bouteiller P., Toubert A., Perarnau B., Roudier J., et al. Serological and structural analysis of HLA class I molecules beta 2-microglobulin interacts with the two external domains of the HLA class I heavy chain . Ann Inst Pasteur Immunol. 138:1987;19.
50. Tanabe M., Sekimata M., Ferrone S., Takiguchi M. Structural and functional analysis of monomorphic determinants recognized by monoclonal antibodies reacting with the HLA class I alpha 3 domain. J Immunol. 148:1992;3202.
51. Boyson J.E., Iwanaga K.K., Golos T.G., Watkins D.I. Identification of a novel MHC class I gene, Mamu-AG, expressed in the placenta of a primate with an inactivated G locus. J Immunol. 159:1997;3311.
52. Slukvin I.I., Boyson J.E., Watkins D.I., Golos T.G. The rhesus monkey analogue of human lymphocyte antigen-G is expressed primarily in villous syncytiotrophoblasts. Biol Reprod. 58:1998;728.
53. Ober C., Aldrich C., Rosinsky B., Robertson A., Walker M.A., Willadsen S., Verp M.S., Geraghty D.E., Hunt J.S. HLA-G1 protein expression is not essential for fetal survival. Placenta. 19:1998;127.
54. Lanier L.L. Natural killer cells fertile with receptors for HLA-G? Proc Natl Acad Sci USA. 96:1999;5343.
55. Braud V.M., Allan D.S., CA O.C., Soderstrom K., A D.A., Ogg G.S., Lazetic S., Young N.T., Bell J.I., Phillips J.H., Lanier L.L., McMichael A.J. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature. 391:1998;795.
56. Lee N., Goodlett D.R., Ishitani A., Marquardt H., Geraghty D.E. HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J Immunol. 160:1998;4951.
57. Llano M., Lee N., Navarro F., Garcia P., Albar J.P., Geraghty D.E., Lopez-Botet M. HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors preferential response to an HLA-G-derived nonamer . Eur J Immunol. 28:1998;1.