Soluble HLA-G in human placentas: Synthesis in trophoblasts and interferon-γ-activated macrophages but not placental fibroblasts

Human Immunology

Volumn 59, Issue 7, 1998, Pages 435-442

  Chu, Wenjiang ^a   Fant, Michael E ^b   Geraghty, Daniel E ^c   Hunt, Joan S ^a,c  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA ANTIGEN; MESSENGER RNA;

ANTIGEN EXPRESSION; ARTICLE; FIBROBLAST; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MACROPHAGE ACTIVATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; CELL LINE; FEMALE; FIBROBLASTS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; MACROPHAGE ACTIVATION; MACROPHAGES; MOLECULAR SEQUENCE DATA; PREGNANCY; PREGNANCY PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOLUBILITY; TROPHOBLASTS;

EID: 0031826168     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(98)00045-7     Document Type: Article

References (39)

1. Sanders S.K., Giblin P.A., Kavathas P. Cell-cell adhesion mediated by CD8 and human histocompatibility leukocyte antigen G, a nonclassical major histocompatibility complex class I molecule on cytotrophoblasts. J Exp Med. 174:1991;737.
2. Kaufman D.S., Schoon R.A., Leibson P.J. MHC class I expression on tumor targets inhibits natural killer cell-mediated cytotoxicity without interfering with target recognition. J Immunol. 150:1993;1429.
3. Chumbley G., King A., Robertson K., Holmes N., Loke Y.W. Resistance of HLA-G and HLA-A2 transfectants to lysis by decidual NK cells. Cell Immunol. 155:1994;312.
4. Moretta A., Sivori S., Vitale M., Pende D., Morelli L., Augugliaro R., Bottino C., Moretta L. Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J Exp Med. 182:1995;875.
5. Kaufman D.S., Schoon R.A., Robertson M.J., Leibson P.J. Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I. Proc Natl Acad Sci USA. 92:1995;6484.
6. Le Bouteiller P. HLA class I genes and products. Hunt J.S. HLA and the maternal-fetal relationship. 1996;51 R.G. Landes, Austin.
7. Diehl M., Munz C., Keiholz W., Stevanovic S., Holmes N., Loke Y.W., Rammensee H. Nonclassical HLA-G molecules are classical peptide presenters. Curr Biol. 6:1996;305.
8. Pazmany L., Mandelboim O., Vales Gomez M., Davis D.M., Reyburn H.T., Strominger J.L. Protection from natural killer cell-mediated lysis by HLA-G expression on target cells. Science. 274:1996;792.
9. Perez Villar J.J., Melero I., Navarro F., Carretero M., Bellon T., Llano M., Colonna M., Geraghty D.E., Lopez Botet M. The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1. J Immunol. 158:1997;5736-5743.
10. Munz C., Holmes N., King A., Loke Y.W., Colonna M., Schild H., Rammensee H.G. Human histocompatibility leukocyte antigen (HLA)-G molecules inhibit NKAT3 expressing natural killer cells. J Exp Med. 185:1997;385-391.
11. Charlton R.K., Zmijewski C.M. Soluble HLA-A7 antigen localization in the beta-lipoprotein fraction of human serum . Science. 170:1970;636.
12. Billing R.J., Safani M., Peterson P. Soluble HLA antigens present in normal human serum. Tissue Antigens. 10:1977;75.
13. Haga J.A., She J.X., Kao K.J. Biochemical characterization of 39-kDa class I histocompatibility antigen in plasma A secretable membrane protein derived from transmembrane domain deletion . J Biol Chem. 266:1991;3695.
14. Krangel M.S. Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway. J Exp Med. 163:1986;1173.
15. Zavazava N., Hausmann R., Muller Ruchholtz W. Inhibition of anti-HLA-B7 alloreactive CTL by affinity-purified soluble HLA. Transplantation. 51:1991;838.
16. Webb B.J., Bochan M.R., Montel A., Padilla L.M., Brahmi Z. The lack of NK cytotoxicity associated with fresh HUCB may be due to the presence of soluble HLA in the serum. Cell Immunol. 159:1994;246.
17. Buelow R., Burlingham W.J., Clayberger C. Immunomodulation by soluble HLA class I. Transplantation. 59:1995;649.
18. Zavazava N., Kronke M. Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes. Nat Med. 2:1996;1005.
19. Carbone E., Terrazzano G., Colonna M., Tuosto L., Piccolella E., Franksson L., Palazzolo G., Perez Villar J.J., Fontana S., Karre K., Zappacosta S. Natural killer clones recognize specific soluble HLA class I molecules. Eur J Immunol. 26:1996;683.
20. Ishitani A., Geraghty D.E. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens. Proc Natl Acad Sci USA. 89:1992;3947.
21. Kirszenbaum M., Moreau P., Gluckman E., Dausset J., Carosella E. An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes. Proc Natl Acad Sci USA. 91:1994;4209-4213.
22. Fujii T., Ishitani A., Geraghty D.E. A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4. J Immunol. 153:1994;5516.
23. Moreau P., Carosella E., Teyssier M., Prost S., Gluckman E., Dausset J., Kirszenbaum M. Soluble HLA-G molecule An alternatively spliced HLA-G mRNA form candidate to encode it in peripheral blood mononuclear cells and human trophoblasts . Hum Immunol. 43:1995;231.
24. Ellis S.A., Palmer M.S., McMichael A.J. Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA class I molecule. J Immunol. 144:1990;731.
25. Kovats S., Main E.K., Librach C., Stubblebine M., Fisher S.J., DeMars R. A class I antigen, HLA-G, expressed in human trophoblasts. Science. 248:1990;220.
26. Yelavarthi K.K., Fishback J.L., Hunt J.S. Analysis of HLA-G mRNA in human placental and extraplacental membrane cells by in situ hybridization. J Immunol. 146:1991;2847.
27. Yang Y., Chu W., Geraghty D.E., Hunt J.S. Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-γ J Immunol. 156:1996;4224.
28. Amiot L., Onno M., Drenou B., le Marchand B., Lamy T., Semana G., Fauchet R. Distribution of HLA-G alternative mRNAs including soluble forms in normal lymphocytes and in lymphoid cell-derived leukemia. Eur J Immunogenet. 23:1996;311.
29. Ober C., Aldrich C.L. HLA-G polymorphisms neutral evolution or novel function? J Reprod Immunol. 36:1997;1.
30. Deniz G., Christmas S.E., Brew R., Johnson P.M. Phenotypic and functional cellular differences between human CD3- decidual and peripheral blood leukocytes. J Immunol. 152:1994;4255.
31. Hunt J.S., Orr H.T. HLA and maternal-fetal recognition. FASEB J. 6:1992;2344.
32. Schmidt C.M., Orr H.T. Maternal/fetal interactions the role of the MHC class I molecule HLA-G . Crit Rev Immunol. 13:1993;207.
33. Fant M.E. In vitro growth rate of placental fibroblasts is developmentally regulated. J Clin Invest. 88:1991;1697.
34. Yang Y., Geraghty D.E., Hunt J.S. Cytokine regulation of HLA-G expression in human trophoblast cell lines. J Reprod Immunol. 29:1995;179.
35. Lee N., Malacko A.R., Ishitani A., Chen M.C., Bajorath J., Marquardt H., Geraghty D.E. The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association. Immunity. 8:1995;591.
36. Hunt J.S., Hsi B.L., King C.R., Fishback J.L. Detection of class I MHC mRNA in subpopulations of first trimester cytotrophoblast cells by in situ hybridization. J Reprod Immunol. 19:1991;315.
37. Blaschitz A., Lenfant F., Mallet V., Hartmann M., Bensussan A., Geraghty D.E., Le Bouteiller P., Dohr G. Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA-G. Eur J Immunol. 27:1997;3380.
38. Haynes M.K., Shepley K.S., Jackson L.G., Tuan R.S., Smith J.B. Cytokine production in first trimester chorionic villi:detection of mRNAs and protein products in situ. Cell Immunol. 151:1993;300.
39. Bulmer J.N., Morrison L., Johnson P.M., Meager A. Immunohistochemical localization of interferons in human placental tissues in normal, ectopic and molar pregnancy. Am J Reprod Immunol. 22:1990;109.