Specific binding of nuclear factors to the HLA-G gene promoter correlates with a lack of HLA-G transcripts in first trimester human fetal liver

Human Immunology

Volumn 59, Issue 12, 1998, Pages 751-757

  Moreau, Philippe ^a,d   Lefebvre, Sophie ^a   Gourand, Luc ^b   Dausset, Jean ^c   Carosella, Edgardo D ^a   Paul, Pascale ^a  

^a Inst Univ d'Hématologie   (France)

^b Hôpital des Metallurgistes   (France)

^c FONDATION JEAN DAUSSET CEPH   (France)

^d SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN; HLA G ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NUCLEAR PROTEIN; RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; DNA PROTEIN COMPLEX; ELECTROPHORETIC MOBILITY; FETUS; FETUS LIVER; FIRST TRIMESTER PREGNANCY; GENETIC TRANSCRIPTION; HISTOCOMPATIBILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOLOGICAL TOLERANCE; NATURAL KILLER CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL LINE; DNA; FEMALE; GENE EXPRESSION REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; LIVER; MICE; NUCLEAR PROTEINS; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 0032402365     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(98)00081-0     Document Type: Article

References (27)

1. Rouas-Freiss N., Marchal-Bras Gonçalves R., Menier C., Dausset J., Carosella E.D. Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis. Proc Natl Acad Sci USA. 94:1997;11520.
2. Carosella E., Dausset J., Kirzenbaum M. HLA-G revisited. Immunol Today. 17:1996;407.
3. Kovats S., Main E.K., Librach C., Stubblebine M., Fisher S.J., DeMars R. A class I antigen, HLA-G, expressed in human trophoblasts. Science. 248:1990;220.
4. Houlihan J.M., Biro P.A., Harper H.M., Jenkinson H.J., Holmes C.H. The human amnion is a site of MHC class Ib expression evidence for the expression of HLA-E and HLA-G . J Immunol. 154:1995;5665.
5. Crisa L., McMaster M.T., Ishii J.K., Fisher S.J., Salomon D.R. Identification of a thymic epithelial cell subset sharing expression of the class Ib HLA-G molecule with fetal trophoblasts. J Exp Med. 186:1997;289.
6. Yang Y., Chu W., Geraghty D.E., Hunt J.S. Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-gamma. J Immunol. 156:1996;4224.
7. Pazmany L., Mandelboim O., Valẽs-Gomez M., Davis D.M., Reyburn H.T., Strominger J.L. Protection from natural killer cell mediated lysis by HLA-G expression on target cells. Science. 274:1996;792.
8. Rouas-Freiss N., Marchal R.E., Kirszenbaum M., Dausset J., Carosella E.D. The alpha-1 domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells Is HLA-G the public ligand for natural killer cell inhibitory receptors? Proc Natl Acad Sci USA. 94:1997;5249.
9. Yokoyama W.M. HLA class I specificity for natural killer cell receptor CD94NKG2A Two for one in more ways than one . Proc Natl Acad Sci USA. 95:1998;4791.
10. Cantoni C., Verdiani S., Falco M., Pessino A., Cilli M., Conte R., Pende D., Ponte M., Mikaelson M.S., Moretta L., Biassoni R. p49, a putative HLA class I-specific inhibitory NK receptor belonging to the Ig superfamily. Eur J Immunol. 28:1998;1980.
11. Colonna M., Navarro F., Bellon T., Llano M., Garcia P., Samaridis J., Angman L., Cella M. a common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med. 186:1997;1809.
12. Colonna M., Samaridis J., Cella M., Angman L., Allen R.L., O'Callaghan C.A., Dunbar R., Ogg G.S., Cerundolo V., Rolink A. Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J Immunol. 160:1998;3096.
13. Geraghty D.E., Koller B.H., Orr H.T. A human major histocompatibility complex class I gene that encodes a protein with shortened cytoplasmic segment. Proc Natl Acad Sci USA. 84:1987;9145.
14. Schmidt C.M., Ehlenfeldt R.G., Athanasiou M.C., Duvick L.A., Heinrichs H., David C.S., Orr H.T. Extraembryonic expression of the human MHC class I gene HLA-G in transgenic mice evidence for a positive regulatory region located 1 kilobase 5′ to the start site of transcription . J Immunol. 151:1993;2633.
15. Schmidt C.M., Orr H.T. HLA-G transgenic mice A model for studying expression and function at the maternal/fetal interface . Immunol Rev. 147:1995;53.
16. Moreau P., Paul P., Gourand L., Prost S., Dausset J., Carosella E.D., Kirszenbaum M. HLA-G gene transcriptional regulation in trophoblasts and blood cells differential binding of nuclear factors to a regulatory element located 1.1 kb from exon 1 . Hum Immunol. 52:1997;41.
17. Ek S., Ringdén O., Markling L., Westgren M. Immunological capacity of human fetal livers cells. Bone Marrow Transplant. 14:1994;9.
18. Gabbianelli M., Boccoli G., Cianetti L., Russo G., Testa U., Peschle C. HLA expression in hemopoietic development class I and class II antigens are induced in the definitive erythroid lineage and differentially modulated by fetal liver cytokines . J Immunol. 144:1990;3354.
19. Houlihan J.M., Biro P.A., Fergar-Payne A., Simpson K.L., Holmes C.H. Evidence for the expression of non-HLA-A,-B,-C class I genes in the human fetal liver. J Immunol. 149:1992;668.
20. Zemmour J., Little A.M., Schendel D.J., Parham P. The HLA-A,B «negative» mutant cell line C1R expresses a novel HLA-B35 allele, which also has a point mutation in the translation initiation codon. J Immunol. 148:1992;1941.
21. Guillaudeux T., Rodriguez A.M., Girr M., Mallet V., Ellis S.A., Sargent I.L., Fauchet R., Alsat E., Le Bouteiller P. Methylation status and transcriptional expression of the MHC class I loci in human trophoblast cells from term placenta. J Immunol. 154:1995;3283.
22. Kirszenbaum M., Moreau P., Gluckman E., Dausset J., Carosella E.D. An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes. Proc Natl Acad Sci USA. 91:1994;4209.
23. Kirszenbaum M., Moreau P., Teyssier M., Lafon C., Gluckman E., Dausset J., Carosella E.D. Evidence for the presence of the alternatively spliced HLA-G mRNA forms in human mononuclear cells from peripheral blood and umbilical cord blood. Hum Immunol. 43:1995;237-241.
24. Onno M., Guillaudeux T., Amiot L., Renard I., Drénou B., Hirel B., Girr M., Semana G., Le bouteiller P., Fauchet R. HLA-G gene is expressed at a low mRNA level in different human cells and tissues. Hum Immunol. 41:1994;79.
25. Teyssier M., Bensussan A., Kirszenbaum M., Moreau P., Gluckman E., Dausset J., Carosella E.D. Natural killer cells are the unique lymphocyte cell subset which do not express HLA-G. Nat Immun. 14:1995;262.
26. Yang Y., Chu W., Geraghty D.E., Hunt J.S. Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-γ J Immunol. 156:1996;4224.
27. Paul P., Rouas-Freiss N., Khalil-Daher I., Moreau P., Riteau B., Le Gal F.A., Avril M.F., Dausset J., Guillet J.G., Carosella E.D. HLA-G expression in melanoma A way for tumor cells to escape from immunosurveillance . Proc Natl Acad Sci USA. 95:1998;4510.