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Volumn 8, Issue 12, 1998, Pages 993-1002

Selection and characterisation of Lactobacillus and Bifidobacterium strains for use as probiotics

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM IDENTIFICATION; BILE; ENVIRONMENT; GENETIC STRAIN; HUMAN; MICROORGANISM SCREENING; MOLECULAR TYPING; PH; PHYSICAL RESISTANCE; PROBE; PROBIOTICS; PROTEIN ANALYSIS; RANDOM AMPLIFIED POLYMORPHIC DNA; SDS POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE HOMOLOGY; SURVIVAL;

EID: 0342744954     PISSN: 09586946     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-6946(99)00024-2     Document Type: Article
Times cited : (337)

References (63)
  • 2
    • 0020466191 scopus 로고
    • Electrophoretic patterns of protein in the genus Bifidobacterium and proposal of four new species
    • Biavati, B., Scardovi, V. and Moore, W. E. C. (1982) Electrophoretic patterns of protein in the genus Bifidobacterium and proposal of four new species. International Journal of Systematic Bacteriology 32, 358-373.
    • (1982) International Journal of Systematic Bacteriology , vol.32 , pp. 358-373
    • Biavati, B.1    Scardovi, V.2    Moore, W.E.C.3
  • 4
    • 0030031126 scopus 로고    scopus 로고
    • 16S rRNA and 16S to 23S internal transcribed spacer sequence analyses reveal inter-and intraspecific Bifidobacterium phylogeny
    • Bourget, L. N., Philippe, H., Mangin, I. and Decaris, B. (1996) 16S rRNA and 16S to 23S internal transcribed spacer sequence analyses reveal inter-and intraspecific Bifidobacterium phylogeny. International Journal of Systematic Bacteriology 46, 102-111.
    • (1996) International Journal of Systematic Bacteriology , vol.46 , pp. 102-111
    • Bourget, L.N.1    Philippe, H.2    Mangin, I.3    Decaris, B.4
  • 5
    • 0030682499 scopus 로고    scopus 로고
    • The use of probiotics to reinforce mucosal defence mechanisms
    • Brassart, D. and Schiffirin, E., (1997) The use of probiotics to reinforce mucosal defence mechanisms. Trends in Food Science and Technology 8, 321-326.
    • (1997) Trends in Food Science and Technology , vol.8 , pp. 321-326
    • Brassart, D.1    Schiffirin, E.2
  • 6
    • 0008874211 scopus 로고
    • In vitro digestibility of protein in yoghurt at various stages of processing
    • Breslaw, E. S. and Kleyn, D. H. (1973) In vitro digestibility of protein in yoghurt at various stages of processing. Journal of Food Science 38, 1016-1021.
    • (1973) Journal of Food Science , vol.38 , pp. 1016-1021
    • Breslaw, E.S.1    Kleyn, D.H.2
  • 7
    • 0028365078 scopus 로고
    • Heterogeneity of bile salts resistance in the Lactobacillus isolates of a probiotic consortium
    • Chateau, N., Descchamps, A. M. and Hadj Sassi, A. (1994) Heterogeneity of bile salts resistance in the Lactobacillus isolates of a probiotic consortium. Letters in Applied Microbiology 18, 42-44.
    • (1994) Letters in Applied Microbiology , vol.18 , pp. 42-44
    • Chateau, N.1    Descchamps, A.M.2    Hadj Sassi, A.3
  • 9
    • 0030746791 scopus 로고    scopus 로고
    • Use of RAPD and 16S rRNA sequencing for the study of Lactobacillus population dynamics in natural whey culture
    • Cocconcelli, P. S., Paris, M. G., Senini, L. and Bottazzi, V. (1997) Use of RAPD and 16S rRNA sequencing for the study of Lactobacillus population dynamics in natural whey culture. Letters in Applied Microbiology 25, 8-12.
    • (1997) Letters in Applied Microbiology , vol.25 , pp. 8-12
    • Cocconcelli, P.S.1    Paris, M.G.2    Senini, L.3    Bottazzi, V.4
  • 10
    • 0024511136 scopus 로고
    • Deoxiribonucleic acid homology studies of Lb. casei, Lb. paracasei sp. nov., subsp. paracasei and subsp. tolerance, and Lb. rhamnosus sp. nov., comb. nov
    • Collins, M. D., Phillips, B. A. and Zanoni, P. (1989) Deoxiribonucleic acid homology studies of Lb. casei, Lb. paracasei sp. nov., subsp. paracasei and subsp. tolerance, and Lb. rhamnosus sp. nov., comb. nov. International Journal of Systematic Bacteriology 39, 105-108.
    • (1989) International Journal of Systematic Bacteriology , vol.39 , pp. 105-108
    • Collins, M.D.1    Phillips, B.A.2    Zanoni, P.3
  • 12
    • 0023087233 scopus 로고
    • Survival of lactic acid bacteria in the human stomach and adhesion to intestinal cells
    • Conway, P. L., Gorbach, S. L. and Goldin, B. R. (1987) Survival of lactic acid bacteria in the human stomach and adhesion to intestinal cells. Journal of Dairy Science 70, 1-12.
    • (1987) Journal of Dairy Science , vol.70 , pp. 1-12
    • Conway, P.L.1    Gorbach, S.L.2    Goldin, B.R.3
  • 14
    • 0002455343 scopus 로고
    • Yoghurt: Nutritive and therapeutic aspects
    • Deeth, H. C. and Tamime, A. Y. (1981) Yoghurt: nutritive and therapeutic aspects. Journal of Food Protection 44, 78-86.
    • (1981) Journal of Food Protection , vol.44 , pp. 78-86
    • Deeth, H.C.1    Tamime, A.Y.2
  • 15
    • 0025176875 scopus 로고
    • Taxonomy of Leuconostoc species, particularly Leuconostoc oenos, as revealed by numerical analysis of total soluble cell protein patterns, DNA base composition, and DNA-DNA hybridisations
    • Dicks, L. M. T., Van Vuuren, H. J. J. and Dellaglio, F. (1990) Taxonomy of Leuconostoc species, particularly Leuconostoc oenos, as revealed by numerical analysis of total soluble cell protein patterns, DNA base composition, and DNA-DNA hybridisations. International Journal of Systematic Bacteriology 40, 83-91.
    • (1990) International Journal of Systematic Bacteriology , vol.40 , pp. 83-91
    • Dicks, L.M.T.1    Van Vuuren, H.J.J.2    Dellaglio, F.3
  • 16
    • 0000335244 scopus 로고    scopus 로고
    • Differentiation of Lb. helveticus strains using molecular typing methods
    • Drake, M. A., Small, C. L., Spence, K. D. and Swanson, B. G. (1996) Differentiation of Lb. helveticus strains using molecular typing methods. Food Research International 29, 451-455.
    • (1996) Food Research International , vol.29 , pp. 451-455
    • Drake, M.A.1    Small, C.L.2    Spence, K.D.3    Swanson, B.G.4
  • 17
    • 0024358339 scopus 로고
    • Fluorometric deoxiribonucleic acid-deoxiribonucleic acid hybridisation in microdilution wells as an alternative to membrane filter hybridisation in which radioisotopes are used to determine genetic relatedness among bacterial strains
    • Ezaki, T., Hashimoto, Y. and Yabuuchi (1989) Fluorometric deoxiribonucleic acid-deoxiribonucleic acid hybridisation in microdilution wells as an alternative to membrane filter hybridisation in which radioisotopes are used to determine genetic relatedness among bacterial strains. International Journal of Systematic Bacteriology 39, 224-229.
    • (1989) International Journal of Systematic Bacteriology , vol.39 , pp. 224-229
    • Ezaki, T.1    Hashimoto, Y.2    Yabuuchi3
  • 19
    • 0030859030 scopus 로고    scopus 로고
    • Influence of various bile salts on β-glucuronidase activity of intestinal bacteria
    • Fujisawa, T. and Mori, M. (1997) Influence of various bile salts on β-glucuronidase activity of intestinal bacteria. Letters in Applied Microbiology 25, 95-97.
    • (1997) Letters in Applied Microbiology , vol.25 , pp. 95-97
    • Fujisawa, T.1    Mori, M.2
  • 21
    • 0345641420 scopus 로고    scopus 로고
    • Enhancement of natural and acquired immunity by Lactobacillus rhamnosus HN001, Lactobacillus acidophilus HN017 and Bifidobacterium lactis HN019
    • submitted
    • Gill, H., Rutherfurd, K., Prasad J. and Gopal, P. (1998) Enhancement of natural and acquired immunity by Lactobacillus rhamnosus HN001, Lactobacillus acidophilus HN017 and Bifidobacterium lactis HN019. British Journal of Nutrition, submitted.
    • (1998) British Journal of Nutrition
    • Gill, H.1    Rutherfurd, K.2    Prasad, J.3    Gopal, P.4
  • 23
    • 0021669414 scopus 로고
    • Importance of bile tolerance of Lb. acidophilus used as a dietary adjunct
    • Gilliland, S. E., Staley, T. E. and Bush, L. J. (1984) Importance of bile tolerance of Lb. acidophilus used as a dietary adjunct. Journal of Dairy Science 67, 3045-3051.
    • (1984) Journal of Dairy Science , vol.67 , pp. 3045-3051
    • Gilliland, S.E.1    Staley, T.E.2    Bush, L.J.3
  • 24
    • 0017716374 scopus 로고
    • Alterations in faecal micro flora enzymes related to diet, age, Lactobacillus supplements and dimethylhydrazine
    • Goldin, B. and Gorbach, S. L. (1977) Alterations in faecal micro flora enzymes related to diet, age, Lactobacillus supplements and dimethylhydrazine. Cancer 40, 2421-2426.
    • (1977) Cancer , vol.40 , pp. 2421-2426
    • Goldin, B.1    Gorbach, S.L.2
  • 27
  • 28
    • 0026553858 scopus 로고
    • Development of diagnostic oligonucleotide probes for four Lactobacillus species occurring in the intestinal tract
    • Hensiek, R., Krupp, G. and Stackebrandt, E. (1992) Development of diagnostic oligonucleotide probes for four Lactobacillus species occurring in the intestinal tract. Systematic and Applied Microbiology 15, 123-128.
    • (1992) Systematic and Applied Microbiology , vol.15 , pp. 123-128
    • Hensiek, R.1    Krupp, G.2    Stackebrandt, E.3
  • 29
    • 84985200341 scopus 로고
    • Effect of low pH on the ability of Lactobacillus acidophilus to survive and adhere to human intestinal cells
    • Hood, S. K. and Zottola, E. A. (1988) Effect of low pH on the ability of Lactobacillus acidophilus to survive and adhere to human intestinal cells. Journal of Food Science 53, 1514-1516.
    • (1988) Journal of Food Science , vol.53 , pp. 1514-1516
    • Hood, S.K.1    Zottola, E.A.2
  • 30
    • 0342683835 scopus 로고    scopus 로고
    • Identification and phylogenetic analysis of Lactobacillus using multiplex RAPD-PCR
    • Khaled, A. K. D., Neilan, B. A., Henricksson, A. and Conway, P. L. (1997) Identification and phylogenetic analysis of Lactobacillus using multiplex RAPD-PCR. FEMS Microbiology Letters 153, 191-197.
    • (1997) FEMS Microbiology Letters , vol.153 , pp. 191-197
    • Khaled, A.K.D.1    Neilan, B.A.2    Henricksson, A.3    Conway, P.L.4
  • 31
    • 0001229718 scopus 로고
    • Lactase activity of cultured and acidified dairy products
    • Kilara, A. and Shahani, K. M. (1976) Lactase activity of cultured and acidified dairy products. Journal of Dairy Science 59, 2031-2035.
    • (1976) Journal of Dairy Science , vol.59 , pp. 2031-2035
    • Kilara, A.1    Shahani, K.M.2
  • 32
    • 0001420383 scopus 로고
    • Genetics of intestinal lactobacilli
    • Klaenhammer, T. R. (1995) Genetics of intestinal lactobacilli. International Dairy Journal 5, 1019-1058.
    • (1995) International Dairy Journal , vol.5 , pp. 1019-1058
    • Klaenhammer, T.R.1
  • 33
    • 0019487590 scopus 로고
    • Growth characteristics, bile sensitivity, and freeze damage in colonial variants of Lb. acidophilus
    • Klaenhammer, T. R. and Kleeman, E. G. (1981) Growth characteristics, bile sensitivity, and freeze damage in colonial variants of Lb. acidophilus. Applied and Environmental Microbiology 41, 1461-1467.
    • (1981) Applied and Environmental Microbiology , vol.41 , pp. 1461-1467
    • Klaenhammer, T.R.1    Kleeman, E.G.2
  • 34
    • 0029043887 scopus 로고
    • Intra-species characterisation of clinical isolates and biotechnologically used strains of Lb. rhamnosus by analysis of the total soluble cytoplasmic proteins with silver staining
    • Klein, G., Hack, B., Hanstein, S., Zimmermann, K. and Reuter, G. (1995) Intra-species characterisation of clinical isolates and biotechnologically used strains of Lb. rhamnosus by analysis of the total soluble cytoplasmic proteins with silver staining. International Journal of Food Microbiology 25, 263-275.
    • (1995) International Journal of Food Microbiology , vol.25 , pp. 263-275
    • Klein, G.1    Hack, B.2    Hanstein, S.3    Zimmermann, K.4    Reuter, G.5
  • 36
    • 0002355794 scopus 로고
    • Survival of Lb. acidophilus and Bifidobacterium spp in the presence of acid and bile
    • Lankaputra, W. E. V. and Shah, N. P. (1995) Survival of Lb. acidophilus and Bifidobacterium spp in the presence of acid and bile. Cultured Dairy Products Journal 30, 2-7.
    • (1995) Cultured Dairy Products Journal , vol.30 , pp. 2-7
    • Lankaputra, W.E.V.1    Shah, N.P.2
  • 37
    • 0026234283 scopus 로고
    • Molecular cloning and DNA polymorphism in Lb. acidophilus and L.gasseri
    • Luchansky, J., Tennant, M. and Klaenhammer, T. (1991) Molecular cloning and DNA polymorphism in Lb. acidophilus and L.gasseri. Journal of Dairy Science 71, 3293-3307.
    • (1991) Journal of Dairy Science , vol.71 , pp. 3293-3307
    • Luchansky, J.1    Tennant, M.2    Klaenhammer, T.3
  • 38
  • 39
    • 0016168624 scopus 로고
    • Studies of a surfactant and cholesteremia in the Maasai
    • Mann, G. V. and Spoerry, A. (1974) Studies of a surfactant and cholesteremia in the Maasai. American Journal of Clinical Nutrition 27, 464-470.
    • (1974) American Journal of Clinical Nutrition , vol.27 , pp. 464-470
    • Mann, G.V.1    Spoerry, A.2
  • 40
    • 0031158713 scopus 로고    scopus 로고
    • Survival of lactic acid bacteria in a dynamic model of stomach and small intestine: Validation and the effects of bile
    • Marteau, P., Minekus, M., Havenaar, R. and Huis In't Veld, J. H. J. (1997) Survival of lactic acid bacteria in a dynamic model of stomach and small intestine: validation and the effects of bile. Journal of Dairy Science 80, 1031-1037.
    • (1997) Journal of Dairy Science , vol.80 , pp. 1031-1037
    • Marteau, P.1    Minekus, M.2    Havenaar, R.3    Huis In't Veld, J.H.J.4
  • 41
    • 0021034485 scopus 로고
    • The adhesion of lactic acid bacteria to the columnar epithelial cells of pigs and calves
    • Mayara-Makinen, A., Manninen, M. and Gyllenberg, H. (1983) The adhesion of lactic acid bacteria to the columnar epithelial cells of pigs and calves. Journal of Applied Bacteriology 55, 241-245.
    • (1983) Journal of Applied Bacteriology , vol.55 , pp. 241-245
    • Mayara-Makinen, A.1    Manninen, M.2    Gyllenberg, H.3
  • 43
    • 0001548475 scopus 로고
    • Role of vitamins and minerals in growth stimulation of rats fed with yoghurt
    • McDonough, F., Wells, P., Wong, N., Hitchins, A. and Bodewell, C. (1983) Role of vitamins and minerals in growth stimulation of rats fed with yoghurt. Federation Proceedings 42, 556-58.
    • (1983) Federation Proceedings , vol.42 , pp. 556-558
    • McDonough, F.1    Wells, P.2    Wong, N.3    Hitchins, A.4    Bodewell, C.5
  • 46
    • 0031204567 scopus 로고    scopus 로고
    • Improvement of lactose digestion by humans following ingestion of unfermented acidophilus milk: Influence of bile sensitivity, lactose transport and acid tolerance of Lb. acidophilus
    • Mustapha, A., Jiang, T. and Savaiano, A. (1997) Improvement of lactose digestion by humans following ingestion of unfermented acidophilus milk: influence of bile sensitivity, lactose transport and acid tolerance of Lb. acidophilus. Journal of Dairy Science 80, 1537-1545.
    • (1997) Journal of Dairy Science , vol.80 , pp. 1537-1545
    • Mustapha, A.1    Jiang, T.2    Savaiano, A.3
  • 47
    • 0030824433 scopus 로고    scopus 로고
    • Biotype and ribotype diversity among Lactobacillus isolates from the mouse ileum
    • Ning, W., Mackie, R. I. and Gaskins, H. R. (1997) Biotype and ribotype diversity among Lactobacillus isolates from the mouse ileum. Systematic and Applied Mic robiology 20, 423-431.
    • (1997) Systematic and Applied Mic Robiology , vol.20 , pp. 423-431
    • Ning, W.1    Mackie, R.I.2    Gaskins, H.R.3
  • 48
    • 0031308824 scopus 로고    scopus 로고
    • Incorporation of cholesterol into the cellular membrane of Lb. acidophilus ATCC 43121
    • Noh, D. O., Kim, S. H. and Gilliland, S. E. (1997) Incorporation of cholesterol into the cellular membrane of Lb. acidophilus ATCC 43121. Journal of Dairy Science 80, 3107-3113.
    • (1997) Journal of Dairy Science , vol.80 , pp. 3107-3113
    • Noh, D.O.1    Kim, S.H.2    Gilliland, S.E.3
  • 49
    • 0031573028 scopus 로고    scopus 로고
    • Determination of genetic diversity within the genus Bifidobacterium and estimation of chromosomal size
    • O'Riordan, K. and Fitzgerald, G. F. (1997) Determination of genetic diversity within the genus Bifidobacterium and estimation of chromosomal size. FEMS Microbiology Letters 156, 259-264.
    • (1997) FEMS Microbiology Letters , vol.156 , pp. 259-264
    • O'Riordan, K.1    Fitzgerald, G.F.2
  • 50
    • 0028305476 scopus 로고
    • Identification of lactic acid bacteria isolated from Portuguese wines and musts by SDS-PAGE
    • Patarata, L., Pimentel, M. S., Pot, B., Kersters, K. and Faia, A. M. (1994) Identification of lactic acid bacteria isolated from Portuguese wines and musts by SDS-PAGE. Journal of Applied Bacteriology 76, 288-293.
    • (1994) Journal of Applied Bacteriology , vol.76 , pp. 288-293
    • Patarata, L.1    Pimentel, M.S.2    Pot, B.3    Kersters, K.4    Faia, A.M.5
  • 52
    • 0029069692 scopus 로고
    • Evaluation of random amplified polymorphic DNA (RAPD)-PCR as a method to differentiate Lb. acidophilus, Lb. crispatus, Lb. amylovorous, Lb. gallinarum, Lb. gasseri and Lb. johnsonii
    • Plessis, E. M. D. and Dicks, L. M. T. (1995) Evaluation of random amplified polymorphic DNA (RAPD)-PCR as a method to differentiate Lb. acidophilus, Lb. crispatus, Lb. amylovorous, Lb. gallinarum, Lb. gasseri and Lb. johnsonii. Current Microbiology 31, 114-118.
    • (1995) Current Microbiology , vol.31 , pp. 114-118
    • Plessis, E.M.D.1    Dicks, L.M.T.2
  • 54
    • 0027156201 scopus 로고
    • Strain characterisation, genome size and plasmid content in the Lb. acidophilus group (Hansen and Mocquot)
    • Roussel, Y., Colmin, C., Simonet, J. M. and Decaris, B. (1993) Strain characterisation, genome size and plasmid content in the Lb. acidophilus group (Hansen and Mocquot). Journal of Applied Bacteriology 74, 549-556.
    • (1993) Journal of Applied Bacteriology , vol.74 , pp. 549-556
    • Roussel, Y.1    Colmin, C.2    Simonet, J.M.3    Decaris, B.4
  • 55
    • 0029870649 scopus 로고    scopus 로고
    • Differentiation of bifidobacteria by use of pulsed-field gel electrophoresis and polymerase chain reaction
    • Roy, D., Ward, P. and Champagne, G. (1996) Differentiation of bifidobacteria by use of pulsed-field gel electrophoresis and polymerase chain reaction. International Journal of Food Microbiology 29, 11-29.
    • (1996) International Journal of Food Microbiology , vol.29 , pp. 11-29
    • Roy, D.1    Ward, P.2    Champagne, G.3
  • 57
    • 0001024359 scopus 로고
    • On the concentration of bile acids in the human intestine during absorption bile acids and steroids 74
    • Sjovall, J. (1959) On the concentration of bile acids in the human intestine during absorption bile acids and steroids 74. Acta Physiologia Scandinavia 46, 339-345.
    • (1959) Acta Physiologia Scandinavia , vol.46 , pp. 339-345
    • Sjovall, J.1
  • 58
    • 21744462018 scopus 로고    scopus 로고
    • Lb. acidophilus M92 as potential probiotic strain
    • Suskovic, J., Brkic, B., Matosic, S. and Maric, V. (1997) Lb. acidophilus M92 as potential probiotic strain. Milchwissenschaft 52, 430-435.
    • (1997) Milchwissenschaft , vol.52 , pp. 430-435
    • Suskovic, J.1    Brkic, B.2    Matosic, S.3    Maric, V.4
  • 59
    • 0030934185 scopus 로고    scopus 로고
    • Development of oligonucleotide primers from the 16S-23S rRNA intergenic sequences for identifying different dairy and probiotic lactic acid bacteria by PCR
    • Timisjarvi, A. T. and Alatossava, T. (1997) Development of oligonucleotide primers from the 16S-23S rRNA intergenic sequences for identifying different dairy and probiotic lactic acid bacteria by PCR. International Journal of Food Microbiology 35, 49-56.
    • (1997) International Journal of Food Microbiology , vol.35 , pp. 49-56
    • Timisjarvi, A.T.1    Alatossava, T.2
  • 60
    • 0028578007 scopus 로고
    • The combined use of whole-cell protein extracts for the identification(SDS-PAGE) and enzyme activity screening of lactic acid bacteria isolated from traditional Greek dairy products
    • Tsakalidou, E., Monolopoulou, E., Kabaraki, E., Zoidou, E., Pot, B., Kersters, K. and Kalantzopoulos, G. (1994) The combined use of whole-cell protein extracts for the identification(SDS-PAGE) and enzyme activity screening of lactic acid bacteria isolated from traditional Greek dairy products. Systematic and Applied Microbiology 17, 444-458.
    • (1994) Systematic and Applied Microbiology , vol.17 , pp. 444-458
    • Tsakalidou, E.1    Monolopoulou, E.2    Kabaraki, E.3    Zoidou, E.4    Pot, B.5    Kersters, K.6    Kalantzopoulos, G.7
  • 62
    • 0031661069 scopus 로고    scopus 로고
    • Two methods for the genetic differentiation of Lactococcus lactis subsp. lactis and cremoris based on differences in the 16S rRNA gene sequence
    • Ward, L. J. H., Brown, J. and Davey, G. P. (1998) Two methods for the genetic differentiation of Lactococcus lactis subsp. lactis and cremoris based on differences in the 16S rRNA gene sequence. FEMS Microbiology Letters 166, 15-20.
    • (1998) FEMS Microbiology Letters , vol.166 , pp. 15-20
    • Ward, L.J.H.1    Brown, J.2    Davey, G.P.3
  • 63
    • 0030197953 scopus 로고    scopus 로고
    • Identification of bifidobacteria from dairy products and evaluation of a micro plate hybridisation method
    • Yaeshima, T., Takahashi, S., Ishibashi, N. and Shimamura, S. (1996) Identification of bifidobacteria from dairy products and evaluation of a micro plate hybridisation method. International Journal of Food Microbiology 30, 303-313.
    • (1996) International Journal of Food Microbiology , vol.30 , pp. 303-313
    • Yaeshima, T.1    Takahashi, S.2    Ishibashi, N.3    Shimamura, S.4


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