Characterization of yeast seryl-tRNA synthetase active site mutants with improved discrimination against substrate analogues

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1480, Issue 1-2, 2000, Pages 160-170

  Landeka, Irena ^a,b   Filipić Ročak, Sanda ^a,b   Žinić, Biserka ^b   Weygand Durašević, Ivana ^a,b  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

Inhibition; Seryl tRNA synthetase; Substrate analogue

Indexed keywords

ADENOSINE DERIVATIVE; HYDROXAMIC ACID; SERINE DERIVATIVE; SERINE TRANSFER RNA LIGASE;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVE SITE; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; YEAST;

KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTAGENESIS; RNA, TRANSFER, SER; SACCHAROMYCES CEREVISIAE; SERINE; SERINE-TRNA LIGASE; SUBSTRATE SPECIFICITY;

SACCHAROMYCES CEREVISIAE;

EID: 0342647021     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(00)00066-2     Document Type: Article

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