Escherichia coli tryptophanyl-tRNA synthetase mutants selected for tryptophan auxotrophy implicate the dimer interface in optimizing amino acid binding

Biochemistry

Volumn 35, Issue 1, 1996, Pages 32-40

  Sever, Sanja ^a,c   Rogers, Kelley ^a,d   Rogers, M John ^a,e   Carter Jr , Charles ^b   Söll, Dieter ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ZAGREB   (Croatia)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRYPTOPHAN; TRYPTOPHAN TRANSFER RNA LIGASE;

ACYLATION; ALPHA HELIX; AMINO ACID METABOLISM; ARTICLE; AUXOTROPHY; DIMERIZATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; BACILLUS STEAROTHERMOPHILUS; BACILLUS SUBTILIS; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; DNA PRIMERS; ESCHERICHIA COLI; GENES, BACTERIAL; HAEMOPHILUS INFLUENZAE; KINETICS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; RESTRICTION MAPPING; SEQUENCE HOMOLOGY, AMINO ACID; TRYPTOPHAN; TRYPTOPHAN-TRNA LIGASE;

ESCHERICHIA COLI; GEOBACILLUS STEAROTHERMOPHILUS;

EID: 0030058138     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952103d     Document Type: Article

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