Independent Molecular Development of Metachronous Glioblastomas with Extended Intervening Recurrence-free Interval

Brain Pathology

Volumn 13, Issue 4, 2003, Pages 598-607

  Martinez, Ramon ^b   Hans K Schackert, ^c   Von Kannen, Stephanie ^c   Lichter, Peter ^a   Joos, Stefan ^a   Schackert, Gabriele ^c  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; NIMUSTINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P14; PROTEIN P16; PROTEIN P53; TEMOZOLOMIDE; TENIPOSIDE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CASE REPORT; CHROMOSOME ABERRATION; COMPARATIVE GENOMIC HYBRIDIZATION; CRANIOTOMY; GENE MUTATION; GLIOBLASTOMA; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MISMATCH REPAIR; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; SECOND CANCER; SURVIVAL TIME; TUMOR RECURRENCE;

EID: 0242667871     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2003.tb00488.x     Document Type: Article

References (34)

1. Bigner SH, Schröck E (1997) Molecular cytogenetics of brain tumors. J Neuropathol Exp Neurol 56:1173-1181.
2. Boland R, Thibodeau S, Hamilton S, Sidransky D, Eshleman J, Rodriguez-Bigas M, Fodde R, Ranzani GN, Srivastava S (1998) A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination for microsatellite instability in colorectal cancer. Cancer Res 58:5248-5257.
3. Bonneau D, Longy M (2000) Mutations of the human PTEN gene. Human Mutat 16:109-122.
4. Burton EC, Lamborn KR, Forsyth P, Scott J, O'Campo J, Uyehara-Lock J, Prados M, Berger M, Passe S, Uhm J, O'Neill B, Jenkins RB, Aldape KD (2002) Aberrant p53, mdm2 and proliferation differ in glioblastomas from long-term compared with typical survivors. Clin Cancer Res 8:180-187.
5. Cawkwell L, Lewis FA, Quirke P (1994) Frequency of allele loss of DCC, p53, RB1, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. Br J Cancer 70:813-818.
6. Cho Y, Gorina S, Jeffrey P Pavletich NP (1994) Crystal structure of a p53 tumor suppressor DNA complex: a framework for understanding how mutations inactivate p53. Science 265:346-355.
7. Collins VP (1998) Gliomas. Cancer Survey 32:37-51.
8. Dietmaier W, Wallinger S, Bocker T, Kullman F, Fishel R and Ruschoff J (1997) Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res 57:4749-4756.
9. Du Manoir S, Schröck E, Bentz M, Speicher MR, Joos S, Ried T, Lichter P, Cremer T (1995) Quantitative analysis of comparative genomic hybridization. Cytometry 19:27-41.
10. Duerr EM, Rollbrocker B, Hayashi Y, Peters N, Meyer-Puttlitz B, Louis DN, Schramm J, Wiestler OD, Parsons R, Eng C, von Deimling A (1998) PTEN mutations in gliomas and glioneuronal tumors. Oncogene 16:2259-2264.
11. Fujisawa H, Kurrer M, Reis RM, Yonekawa Y, Kleihues P, Ohgaki H (1999) Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter. Am J Pathol 155:387-394.
12. Greenblatt MS, Bennett M, Hollstein M, Harris CC (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878.
13. Hahn M, Wieland I, Koufaki ON, Görgens H, Sobottka SB, Schackert G, Schackert HK (1999) Genetic alterations of the tumor suppressor gene PTEN/MMAC1 in human brain metastases. Clin Cancer Res 5:2431-2437.
14. Hainaut P, Soussi T, Shomer B, Hollstein M, Greenblatt M, Hovig E, Harris CC, Montesano R (1997) Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects. Nucleic Acids Res 25:151-157.
15. Hayashi Y, Ueki K, Waha A, Wiestler OD, Louis DN, von Deimling A (1997) Association of gene amplification and CDKN2A(p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathol 7:871-875.
16. Joos S, Bergerheim USR, Pan Y, Matsuyama H, Bentz M, du Manoir S, Lichter P (1995) Mapping of chromosomal gains and losses in prostate cancer by comparative genomic hybridization. Genes Chromosomes Cancer 14:267-276.
17. Joos S, Otaño-Joos MI, Ziegler S, Brüderlein S, du Manoir S, Bentz M, Möller P, Lichter P (1996) Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene. Blood 87:1571-1578.
18. Kleihues P, Ohgaki H (1999) Primary and secondary glioblastomas: from concept to clinical diagnosis. Neurooncol 1:44-51.
19. Kraus JA, Lamszus K, Glesmann N, Beck M, Wolter M, Sabel M, Krex D, Klockgether T, Reifenberger G, Schlegel U (2001) Molecular genetic alterations in glioblastomas with oligodendroglial component. Acta Neuropathol 101:311-320.
20. Lacroix M, Abi-Said D, Fourney DR, Gokaslan ZL, Shi W, DeMonte F, Lang FF, McCutcheon IE, Hassenbusch SJ, Holland E, Hess K, Michael C, Miller D, Sawaya R (2001) A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection and survival. J Neurosurg 95:190-198.
21. Liaw D, Marsh DJ, Li J, Dahia PL, Wang SI, Zheng Z, Bose S, Call KM, Tsou HC, Peacocke M, Eng C, Parsons R (1997) Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16:64-67.
22. Louis DN (1997) A molecular genetic model of astrocytoma histopathology. Brain Pathol 7:755-764.
23. Morse RP, Darras BT, Ye Z, Wu JK (1994) Clonal analysis of human astrocytomas. J Neurooncol 21:151-157.
24. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali R, Harris CC, Vogelstein B (1989) Mutations in the p53 gene occur in diverse human tumor types. Nature 342:705-708.
25. Plaschke J, Kruger S, Pistorius S, Theissig F, Saeger HD, Schackert HK (2002) Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. Int J Cancer 97:643-648.
26. Reis RM, Herva R, Brandner S, Koivukangas J, Mironov N, Bär W, Kleihues P, Ohgaki H (2001) Second primary glioblastoma. J Neuropathol Exp Neurol 60:208-215.
27. Rollbrocker B, Waha A, Louis DN, Wiestler OD, von Deimling A (1996) Amplification of the cyclin dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme. Acta Neuropathol 92:70-74.
28. Saxena A, Shriml L, Dean M, Ali IU (1999) Comparative molecular genetic profiles of anaplastic astrocytomas/glioblastomas multiforme and their subsequent recurrences. Oncogene 18:1385-1390.
29. Scott JN, Rewcastle NB, Brasher PMA, Fulton D, Hagen NA, MacKinnon JA, Hamilton M, Cairncross JC, Forsyth P (1999) Which glioblastoma multiforme patient will become a long-term survivor? A population based study. Ann Neurol 46:183-188.
30. Smith JS, Perry A, Borell TJ, Lee HK, O'Fallon J, Hosek SM, Kimmel D, Yates A, Burger PC, Scheithauer BW, Jenkins RB (2000) Alterations of chromosome arms 1 p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas. J Clin Oncol 18:636-645.
31. Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DH, Tavtigian SV (1997) Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advances cancers. Nat Genet 15:356-362.
32. Tada M, Sawamura Y, Abe H, Iggo R (1997) Homozygous p53 gene mutation in a radiation-induced glioblastoma 10 years after treatment for an intracranial germ-cell tumor: case report. Neurosurgery 40:393-396.
33. Von Deimling A, Louis DN, Wiestler OD (1995) Molecular pathways in the formation of gliomas. Glia 15:328-338.
34. Von Deimling A, von Ammon K, Schoenfeld D, Wiestler OD, Seizinger BR, Louis DN (1993) Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol 3:19-26.