Molecular cytogenetics of brain tumors

Journal of Neuropathology and Experimental Neurology

Volumn 56, Issue 11, 1997, Pages 1173-1181

  Bigner, Sandra H ^a   Schröck, Evelin ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

Brain tumors; Chromosomes; Comparative genomic hybridization; Fluorescence in situ hybridization; Genes; Glioma; Medulloblasmma

Indexed keywords

DNA;

BRAIN TUMOR; CHROMOSOME 10; CHROMOSOME 17Q; CHROMOSOME 7; CHROMOSOME 9P; CHROMOSOME ABERRATION; CHROMOSOME DELETION; CHROMOSOME LOSS; CHROMOSOME PAINTING; CYTOGENETICS; DNA HYBRIDIZATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GLIOBLASTOMA; HUMAN; ISOCHROMOSOME; KARYOTYPING; MEDULLOBLASTOMA; MOLECULAR GENETICS; PRIORITY JOURNAL; REVIEW; SUPERNUMERARY CHROMOSOME;

EID: 1842290325     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199711000-00001     Document Type: Review

References (74)

1. Zang KD, Singer H. Chromosomal constitution of meningiomas. Nature 1967;216:84-85
2. Zankl H, Zang KD. Cytological and cytogenetical studies on brain tumors. IV. Identification of the missing G chromosome in human meningiomas as No. 22 by fluorescence technique. Humangenetik 1972;14:167-69
3. Seizinger BR, De La Monte S, Atkins L, Gusella JF, Martuza RI. Molecular genetic approach to human meningiomas: Loss of genes on chromosomes. Proceedings of the National Academy of Science, U.S.A. 1987;84:5419-23
4. Rouleau GA, Merel P, Lutchman M, et al. Alteration in a new gene encoding a putative membrane-organizing protein causes neurofibromatosis type 2. Nature 1993;363:515-21
5. Trofatter JA, MacCollin MM, Rutter JL, et al. A novel Moesin-, Ezrin-, Radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell 1993;72:791-800
6. Bigner SH, Mark J, Burger PC, et al. Specific chromosomal abnormalities in malignant human gliomas. Cancer Res 1988;48:405-11
7. Bigner SH, Wong AJ, Mark J, et al. Relationship between gene amplification and chromosomal deviations in malignant human gliomas. Cancer Genet Cytogenet 1987;29:165-70
8. Jen JJ, Harper JW, Bigner SH, et al. Deletion of p16 and p15 genes in brain tumors. Cancer Res 1994;54:6353-58
9. Ransom DT, Ritland SR, Moertel CA, et al. Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligoastrocytomas. Genes, Chromosomes and Cancer 1992;5:357-74
10. Rasheed BK, McLendon RE, Friedman HS, et al. Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25. Oncogene 1995;10:2243-46
11. Karlbom AE, James CD, Boethius J, et al. Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10. Hum Genet 1993;92:169-74
12. Fults D, Pedone C. Deletion mapping of the long arm of chromosome 10 in glioblastoma multiform. Genes, Chromosomes and Cancer 1993;7:173-77
13. Kimmelman AC, Ross DA, Liang BC. Loss of heterozygosity of chromosome 1Op in human gliomas. Genomics 1996;34:250-54
14. Li J, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997; 275:1943-47
15. Steck PA, Pershouse MA, Jasser SA, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancer. Nature Genet 1997; 15:356-62
16. Bigner SH, Mark J, Friedman HS, Biegel JA, Bigner DD. Structural chromosomal abnormalities in human medulloblastomas. Cancer Genet Cytogenet 1988;30:91-101
17. Griffin CA, Hawkins AL, Packer RJ, Rorke LB, Emanuel BS. Chromosome abnormalities in pediatric brain tumors. Cancer Res 1988;48:175-80
18. Ohgaki H, Eibl RH, Wiestler OD, Yasargil MG, Newcomb EW, Kleihues P. P53 mutations in nonastrocytic human brain tumors. Cancer Res 1991;51:6202-5
19. Biegel JA, Burk CD, Barr FG, Emanuel BS. Evidence for a 17p tumor related locus distinct from p53 in pediatric primitive neuroectodermal tumors. Cancer Res 1992;52:3391-95
20. Adesina AM, Nalbantoglu J, Cavenee WK. p53 Gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res 1994;54:5649-51
21. Batra SK, McLendon RE, Koo JS, et al. Prognostic implications of chromosome 17q deletions in human medulloblastomas. J Neurooncol 1995b;24:39-45
22. Bigner SH, Friedman HS, Vogelstein B, Oakes WJ, Bigner DD. Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts. Cancer Res 1990;50:2347-50
23. Tenan M, Colombo BM, Polio B, Cajola L, Broggi G, Finoocchiaro G. P53 mutations and microsatellite analysis of loss of heterozygosity in malignant gliomas. Cancer Genet Cytogenet 1994;74: 139-43
24. Rasheed BK, McLendon RE, Herndon JE, Friedman HS, Friedman AH, Bigner DD, Bigner SH. Alternations of the TP53 gene in human gliomas. Cancer Res 1994;54:1324-30
25. von Deimling A, von Ammon K, Schoenfeld D, Wiestler OD, Seizinger BR, Louis DN. Subsets of glioblastoma multiform defined by molecular genetic analysis. Brain Pathol 1993;3:19-26
26. Lang FF, Miller DC, Koslow M, Newcomb EW. Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors. J Neurosurg 1994;81:427-36
27. Ohgaki H, Schäuble B, zur Hausen A, von Ammon K, Kleihues P. Genetic alterations associated with the evolution and progression of astrocytic brain tumours. Virchows Archiv 1995;427:113-18
28. Reifenberger J, Ring GU, Gies U, et al. Analysis of p53 mutations and epidermal growth factor receptor amplification in recurrent gliomas with malignant progression. J Neuropathol Exp Neurol 1996;55:822-31
29. Louis DN. Clinicopatho-genetic subsets of glioblastoma multiforme: From both sides now [editorial]. Brain Pathol 1996;6:223-24
30. Watanabe K, Tachibana O, Sato K, Yonekawa Y, Kleihues P, Ohgaki H. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 1996;6:217-23
31. von Deimling A, Louis DN, von Ammon K, Petersen I, Wiestler OD, Seizinger BR. Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas. Cancer Res 1992;52:4277-79
32. Rosenberg JE, Lisle DK, Burwick JA, Ueki K, von Deimling A, Mohrenweiser HW, Louis DN. Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval. Oncogene 1996;13:2483-85
33. Pinkel DT, Straume T, Gray JW. Cytogenetic analysis using quantitative, high-sensitivity fluorescence hybridization. Proc Natl Acad Sci USA 1986;83:2934-38
34. Arnoldus EPJ, Wolters LBT, Voormolen JHC, van Dunen SG, Raap AK, van der Pleog M, Peters ACB. Interphase cytogenetics: A new tool for the study of genetic changes in brain tumors. J Neurosurg 1992;76:997-1003
35. Lõw M, Feiden W, Moringlane JR, Zang KD, Henn W. Detection of numerical chromosome aberrations in brain tumours by fluorescence in situ hybridization on smear preparations of small tumour biopsies. Neuropathol Appl Neurobiol 1994;20:432-38
36. Kwak T, Nishizaki T, Ito H, Kimura Y, Murakami T, Sasaki K. Flow-cytometric quantification in human gliomas of alpha satellite DNA sequences specific for chromosome 7 using fluorescence in situ hybridization. Cytometry 1994;17:26-32
37. Schneider BF, Shashi V, von Kap-herr C, Golden WL. Loss of chromosomes 22 and 14 in the malignant progression of meningiomas. A comparative study of fluorescence in situ hybridization (FISH) and standard cytogenetic analysis. Cancer Genet Cytogenet 1995; 85:101-4
38. Yu I-Ting, Griffin CA, Phillips PC, Strauss LC, Perlman EJ. Numerical sex chromosomal abnormalities in pineal teratomas by cytogenetic analysis and fluorescence In situ hybridization. Lab Invest 1995;72:419-23
39. Donovan MJ, Yunis EJ, DeGirolami U, Fletcher JA, Schofield DE. Chromosome aberrations in choroid plexus papillomas. Genes, Chromosomes & Cancer 1994;11:267-70
40. White FV, Anthony DC, Yunis EJ, Tarbell NJ, Scott RM, Schofield DE. Nonrandom chromosomal gains in pilocytic astrocytomas of childhood. Human Pathol 1995;26:979-86
41. Dalrymple SJ, Herath JE, Borell TJ, Moertel CA, Jenkins RB. Correlation of cytogenetic and fluorescence In situ hybridization (FISH) studies in normal and gliotic brain. J Neuropathol Exp Neurol 1994;53:448-56
42. Hecht BK, Turc-Carel C, Chatel M, et al. Cytogenetics of malignant gliomas. II. The sex chromosomes with reference to X isodisomy and the role of numerical X/Y changes. Cancer Genet Cytogenet 1995;84:9-14
43. Park SH, Maeda T, Mohapatra G, Waldman FM, Davis, RL, Feuerstein BG. Heterogeneity, polyploidy, aneusomy, and 9p deletion in human glioblastoma multiform. Cancer Genet Cytogenet 1995;83: 127-35
44. Feuerstein BG, Mohapatra G. Molecular cytogenetic quantitation of gains and losses of genetic material from human gliomas. J Neurooncol 1995;24:47-55
45. Dreyling MH, Bohlander SK, Adeyanju MO, Olopade OI. Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in Situ hybridization. Cancer Res 1995; 55:984-88
46. Hashimoto N, Ichikawa D, Arakawa Y, et al. Frequent deletions of material from chromosome arm 1p in oligodendroglial tumors revealed by double-target fluorescence in situ hybridization and microsatellite analysis. Genes, Chromosomes & Cancer 1995;14:295-300
47. Wernicke C, Thiel G, Lozanova T, Vogel S, Witkowski R. Numerical aberrations of chromosomes 1, 2, and 7 in astrocytomas studied by interphase cytogenetics. Genes, Chromosomes & Cancer 1997; 19:6-13
48. Vagner-Capodano AM, Zattara-Cannoni H, Gambarelli D, et al. Detection if i(17q) chromosome by fluorescent in situ hybridization (FISH) with interphase nuclei in medulloblastoma. Cancer Genet Cytogenet 1994;78:1-6
49. Scheurlen WG, Seranski P, Mincheva A, et al. High-resolution deletion mapping of chromosome arm 17p in childhood primitive neuroectodermal tumors reveals a common chromosomal disruption within the Smith-Magenis region, an unstable region in chromosome band 17p11.2. Genes, Chromosomes & Cancer 1997;18:50-58
50. McKeever PE, Dennis TR, Burgess AC, Meltzer PS, Marchuk, DA, Trent JM. Chromosome breakpoint of 17q11.2 and insertion of DNA from three different chromosomes in a glioblastoma with exceptional glial fibrillary acidic protein expression. Cancer Genet Cytogenet 1996;87:41-47
51. Klopfenstein K, Soukup S, Blough R, et al. Chromosome analyses in a rhabdoid tumor of the brain. Cancer Genet Cytogenet 1997; 93:152-56
52. Giollant J, Bertrand S, Verrelle P. Characterization of double minute chromosomes' DNA content in a human high grade astrocytoma cell line by using comparative genomic hybridization and fluorescence in situ hybridization. Human Genet 1996;98:265-70
53. Muleris M, Almeida A, Dutrillaux AM, et al. Oncogene amplification in human gliomas: A molecular cytogenetic analysis. Oncogene 1994;9:2717-22
54. Speicher MR, Ballard SG, Ward DC. Computer image analysis of combinatorial multi-fluor FISH. Bioimaging 1996;4:52-64
55. Speicher MR, Ballard SG, Ward DC. Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nature Genet 1996; 12:368-75
56. Le Beau MM. One FISH, two FISH, red FISH, blue FISH. Nature Genet 1996;12:341-44
57. Schröck E, Du Manoir S, Veldman T, et al. Multicolor spectral karyotyping of human chromosomes. Science 1996;273:494-97
58. Liyanage M, Coleman A, Du Manoir S, et al. Multicolour spectral karyotyping of mouse chromosomes. Nature Genet 1996;14:312-15
59. Garini Y, Macville M, du Manior S, et al. Spectral karyotyping. Bioimaging 1996;4:65-72
60. Schröck E, et al. Human molecular genetics. Submitted.
61. Veldman T, Vignon C, Schröck E, Rowley JD, Ried T. Hidden chromosomal abnormalities in hematological malignancies detected by multicolor spectral karyotyping. Nature Genet 1997; 15:406-10
62. Kallioniemi A, Kallioniemi Olli-P, Sudar D, et al. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 1992;258:818-21
63. Houldsworth J, Chaganti RSK. Comparative genomic hybridization: An overview. Am J Pathol 1994;145:1253-60
64. Du Manoir S, Speicher MR, Joos S, et al. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization. Human Genet 1993;90:590-610
65. Speicher MR, Du Manoir S, Schröck E, et al. Molecular cytogenetic analysis of formalin fixed, paraffin embedded solid tumors by comparative genomic hybridization after universal DNA amplification. Human Mol Genet 1993;2:1907-14
66. Schröck E, Thiel G, Lozanova T, et al. Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and nonrandom chromosomal gains and losses. Am J Pathol 1994;144:1203-18
67. Mohapatra G, Kim DH, Feuerstein BG. Detection of multiple gains and losses of genetic material in ten glioma cell lines by comparative genomic hybridization. Genes, Chromosomes & Cancer 1995; 13:86-93
68. Schlegel J, Scherthan H, Arens N, Stumm G, Kiessling M. Detection of complex genetic alterations in human glioblastoma multiform using comparative genomic hybridization. J Neuropathol Exp Neurol 1996;55:81-87
69. Boerman RH, Anderl K, Herath J, et al. The glial and mesenchymal elements of gliosarcomas share similar genetic alterations. J Neuropathol Exp Neurol 1996;55:973-81
70. Schröck E, Blume C, Meffert M-C, et al. Recurrent gain of chromosome arm 7q in low-grade astrocytic tumors studied by comparative genomic hybridization. Genes, Chromosomes & Cancer 1996;15:199-205
71. Weber RG, Sabel M, Reifenberger J, et al. Characterization of genomic alterations associated with glioma progression of comparative genomic hybridization. Oncogene 1996;13:983-94
72. Weber RG, Sommer C, Albert FK, Kiessling M, Cremer T. Clinically distinct subgroups of glioblastoma multiform studies by comparative genomic hybridization. Lab Invest 1996;74:108-19
73. Schütz BR, Scheurlen W, Krauss J, et al. Mapping of chromosomal gains and losses in primitive neuroectodermal tumors by comparative genomic hybridization. Genes, Chromosomes & Cancer 1996; 16:196-203
74. Bayani J, Thorner P, Zielenska M, Pandita A, Beatty B, Squire JA. Application of a simplified comparative genomic hybridization technique to screen for gene amplification in pediatric solid tumors. Ped Pathol Lab Med 1995;15:831-44