Pro-apoptotic Activity of HIV-1 Auxiliary Regulatory Protein Vpr Is Subtype-dependent and Potently Enhanced by Nonconservative Changes of the Leucine Residue at Position 64

Journal of Biological Chemistry

Volumn 278, Issue 45, 2003, Pages 44326-44330

  Jian, Heng ^b   Zhao, Ling Jun ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYST ACTIVITY; CELLS; DEGRADATION; DNA; SUBSTITUTION REACTIONS; TISSUE;

APOPTOSIS;

PROTEINS;

ALANINE; ARGININE; CASPASE; DNA; DNA FRAGMENT; LEUCINE; MUTANT PROTEIN; PROLINE; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; REGULATOR PROTEIN; VPR PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC RECOMBINATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOTHESIS; MOLECULE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; APOPTOSIS; CASPASES; CELL LINE; DNA; DNA FRAGMENTATION; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION; GENE PRODUCTS, VPR; HIV-1; HUMANS; KIDNEY; LEUCINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0242666392     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300378200     Document Type: Article

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