Evaluation of a New Norepinephrine Transporter PET Ligand in Baboons, Both in Brain and Peripheral Organs

Synapse

Volumn 50, Issue 4, 2003, Pages 345-352

  Ding, Yu Shin ^a   Lin, Kuo Shyan ^a   Garza, Victor ^a   Carter, Pauline ^a   Alexoff, David ^a   Logan, Jean ^a   Shea, Colleen ^a   Xu, Youwen ^a   King, Payton ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Antidepressant; C 11; Norepinephrine transporter; Positron emission tomography; Reboxetine

Indexed keywords

CARBON 11; DESIPRAMINE; METHYL GROUP; METHYLREBOXETINE; NISOXETINE; NORADRENALIN TRANSPORTER; RADIOLIGAND; UNCLASSIFIED DRUG; VANOXERINE;

ANIMAL EXPERIMENT; ARTICLE; BABOON; BRAIN; CEREBELLUM; CHIRAL CHROMATOGRAPHY; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; ENANTIOMER; ENANTIOSELECTIVITY; FEMALE; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGE ANALYSIS; IMAGING; IMAGING SYSTEM; IN VIVO STUDY; ISOMER; NONHUMAN; ORGAN; POSITRON EMISSION TOMOGRAPHY; PRECURSOR; PRIORITY JOURNAL; RACEMIC MIXTURE; RADIOACTIVITY; RODENT; STATISTICAL SIGNIFICANCE; THALAMUS; TISSUE DISTRIBUTION; TISSUE SPECIFICITY; TRUNK;

ANIMALS; AUTORADIOGRAPHY; BINDING, COMPETITIVE; BRAIN; BRAIN CHEMISTRY; BRAIN MAPPING; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART; KIDNEY; LIVER; LUNG; MORPHOLINES; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PAPIO; RADIOLIGAND ASSAY; STEREOISOMERISM; SYMPORTERS; TIME FACTORS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0242653791     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.10281     Document Type: Article

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