Chiral drugs: Comparison of the pharmacokinetics of [11C]d-threo and l-threo-methylphenidate in the human and baboon brain

Psychopharmacology

Volumn 131, Issue 1, 1997, Pages 71-78

  Ding, Y S ^a   Fowler, J S ^a   Volkow, N D ^b   Dewey, S L ^a   Wang, G J ^a   Logan, J ^a   Gatley, S J ^a   Pappas, N ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Chiral drugs; Dopamine transporter; Methylphenidate; Positron emission tomography; Ritalin; Stereoselectivity

Indexed keywords

CARBON 11; DOPAMINE; METHYLPHENIDATE; VANOXERINE;

ANIMAL EXPERIMENT; ARTICLE; BABOON; BASAL GANGLION; CEREBELLUM; CHIRALITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BINDING; DRUG DISTRIBUTION; DRUG UPTAKE; ENANTIOMER; FEMALE; HUMAN; HUMAN EXPERIMENT; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; NORMAL HUMAN; PHARMACOKINETICS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RACEMIC MIXTURE; RAT;

AGED; ANIMALS; BRAIN; FEMALE; HUMANS; MALE; METHYLPHENIDATE; MIDDLE AGED; PAPIO; RADIOLIGAND ASSAY; STEREOISOMERISM; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0030941402     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050267     Document Type: Article

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