Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: Therapeutic implications

Synapse

Volumn 43, Issue 3, 2002, Pages 181-187

  Volkow, Nora D ^a,b   Wang, Gene Jack ^a   Fowler, Joanna S ^a   Logan, Jean ^a   Franceschi, Dinko ^a   Maynard, Laurence ^a   Ding, Yu Shin ^a   Gatley, Samuel J ^a   Gifford, Andrew ^a   Zhu, Wei ^c   Swanson, James M ^d  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c Stony Brook University   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Attention deficit hyperactivity disorder; DA receptors; Imaging; Raclopride; Ritalin; Striatum

Indexed keywords

COCAINE; DOPAMINE; DOPAMINE TRANSPORTER; METHYLPHENIDATE; RACLOPRIDE;

ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; CORPUS STRIATUM; DOPAMINE BRAIN LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ADULT; AGE FACTORS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BEHAVIOR; BRAIN; CARBON RADIOISOTOPES; CARDIOVASCULAR PHYSIOLOGY; COCAINE; DOPAMINE; DOPAMINE ANTAGONISTS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; EXTRACELLULAR SPACE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT MODULATORS; MEMBRANE TRANSPORT PROTEINS; METHYLPHENIDATE; NEOSTRIATUM; NERVE TISSUE PROTEINS; NEURONS; RACLOPRIDE; TOMOGRAPHY, EMISSION-COMPUTED; UP-REGULATION;

EID: 0036497938     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.10038     Document Type: Article

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