Synthesis and biological evaluation of fluorescently labeled epothilone analogs for tubulin binding studies

Tetrahedron

Volumn 59, Issue 50, 2003, Pages 9979-9984

  Ganesh, Thota ^a   Schilling, Jennifer K ^a   Palakodety, Radha K ^a   Ravindra, Rudravajhala ^b   Shanker, Natasha ^b   Bane, Susan ^b   Kingston, David G I ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b BINGHAMTON UNIVERSITY   (United States)

Author keywords

Bioactivity; Epothilone; Fluorescence; Tubulin

Indexed keywords

EPOTHILONE DERIVATIVE; PACLITAXEL; TUBULIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CELL LINE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG ACTIVITY; DRUG BINDING; DRUG SYNTHESIS; FEMALE; FLUORESCENCE; HUMAN; HUMAN CELL; IC 50; MALE; MICROTUBULE; NICOLAU MACROLACTONIZATION; OVARY CANCER; PRIORITY JOURNAL; STILLE COUPLING STRATEGY;

EID: 0242635942     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.10.024     Document Type: Article

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