메뉴 건너뛰기




Volumn 285, Issue 6 54-6, 2003, Pages

Ca2+-dependent inhibition of NHE3 requires PKCα which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes

Author keywords

Na absorption; PDZ domains; Signal complex

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CALCIUM; IONOMYCIN; PROTEIN E3KARP; PROTEIN KINASE C ALPHA; PROTEIN KINASE C INHIBITOR; REGULATOR PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; ENZYME INHIBITOR; PHOSPHOPROTEIN; PROTEIN KINASE C; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER 3; SODIUM-HYDROGEN EXCHANGER REGULATORY FACTOR;

EID: 0242594703     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00017.2003     Document Type: Article
Times cited : (91)

References (55)
  • 1
    • 0032778706 scopus 로고    scopus 로고
    • Phorbol ester promotes endocytosis by activating a factor involved in endosomal fusion
    • Aballay A, Stahl PD, and Mayorga LS. Phorbol ester promotes endocytosis by activating a factor involved in endosomal fusion. J Cell Sci 112: 2549-2557, 1999.
    • (1999) J Cell Sci , vol.112 , pp. 2549-2557
    • Aballay, A.1    Stahl, P.D.2    Mayorga, L.S.3
  • 2
    • 0342657745 scopus 로고    scopus 로고
    • Effect of a tyrosine 155 to phenylalanine mutation of protein kinase C delta on the proliferative and tumorigenic properties of NHE3 fibroblasts
    • Acs P, Beheshti M, Szallasi Z, Li L, Yuspa SH, and Blumberg PM. Effect of a tyrosine 155 to phenylalanine mutation of protein kinase C delta on the proliferative and tumorigenic properties of NHE3 fibroblasts. Carcinogenesis 21: 887-891, 2000.
    • (2000) Carcinogenesis , vol.21 , pp. 887-891
    • Acs, P.1    Beheshti, M.2    Szallasi, Z.3    Li, L.4    Yuspa, S.H.5    Blumberg, P.M.6
  • 4
    • 0026073228 scopus 로고
    • Regulation of receptor-mediated endocytosis by phorbol esters
    • Backer JM and King GL. Regulation of receptor-mediated endocytosis by phorbol esters. Biochem Pharmacol 41: 1267-1277, 1991.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1267-1277
    • Backer, J.M.1    King, G.L.2
  • 5
    • 0035971106 scopus 로고    scopus 로고
    • Active (9.6.s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border
    • Biemesderfer D, DeGray B, and Aronson PS. Active (9.6.s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border. J Biol Chem 276: 10161-10167, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 10161-10167
    • Biemesderfer, D.1    DeGray, B.2    Aronson, P.S.3
  • 8
    • 0035172705 scopus 로고    scopus 로고
    • Protein phosphorylation is required for endocytosis in nerve terminals: Potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin
    • Cousin MA, Tan TC, and Robinson PJ. Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin. J Neurochem 76: 105-116, 2001.
    • (2001) J Neurochem , vol.76 , pp. 105-116
    • Cousin, M.A.1    Tan, T.C.2    Robinson, P.J.3
  • 9
    • 0033544844 scopus 로고    scopus 로고
    • Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
    • Daniels GM and Amara SG. Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters. J Biol Chem 274: 35794-35801, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 35794-35801
    • Daniels, G.M.1    Amara, S.G.2
  • 10
    • 0034724969 scopus 로고    scopus 로고
    • Inhibition of protein kinase C counteracts TNFα-induced intercellular adhesion molecule 1 expression and fluid phase endocytosis on brain microvascular cells
    • Defazio G, Nico B, Trojano M, Ribatti D, Giorelli M, Ricchiuti F, Martino D, Roncali L, and Livrea P. Inhibition of protein kinase C counteracts TNFα-induced intercellular adhesion molecule 1 expression and fluid phase endocytosis on brain microvascular cells. Brain Res 863: 245-248, 2000.
    • (2000) Brain Res , vol.863 , pp. 245-248
    • Defazio, G.1    Nico, B.2    Trojano, M.3    Ribatti, D.4    Giorelli, M.5    Ricchiuti, F.6    Martino, D.7    Roncali, L.8    Livrea, P.9
  • 11
    • 0020803854 scopus 로고
    • Calcium in the control of active intestinal Na and Cl transport and involvement in neurohumoral action
    • Donowitz M. Calcium in the control of active intestinal Na and Cl transport and involvement in neurohumoral action. Am J Physiol Gastrointest Liver Physiol 245: G165-G177, 1983.
    • (1983) Am J Physiol Gastrointest Liver Physiol , vol.245
    • Donowitz, M.1
  • 13
    • 0020424208 scopus 로고
    • Calcium content in rabbit ileum is increased by the neurohumoral secretagogues serotonin, carbachol, substance P and neurotensin
    • Donowitz M, Fogel R, Battisti L, and Asarkof N. Calcium content in rabbit ileum is increased by the neurohumoral secretagogues serotonin, carbachol, substance P and neurotensin. Life Sci 31: 1929-1937, 1982.
    • (1982) Life Sci , vol.31 , pp. 1929-1937
    • Donowitz, M.1    Fogel, R.2    Battisti, L.3    Asarkof, N.4
  • 14
    • 0027505810 scopus 로고
    • A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor
    • Eichholtz T, deBont DB, de Widt J, Liskamp RM, and Ploegh HL. A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor. J Biol Chem 268: 1982-1986, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 1982-1986
    • Eichholtz, T.1    DeBont, D.B.2    De Widt, J.3    Liskamp, R.M.4    Ploegh, H.L.5
  • 15
    • 0028101308 scopus 로고
    • + exchanger isoforms NHE1 and NHE3 exist as stable dimmers in membranes with a high degree of specificity for homodimers
    • + exchanger isoforms NHE1 and NHE3 exist as stable dimmers in membranes with a high degree of specificity for homodimers. J Biol Chem 269: 2589-2596, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 2589-2596
    • Fafournoux, P.1    Noel, J.2    Pouyssegur, J.3
  • 16
    • 0028956320 scopus 로고
    • Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
    • Holm PK, Eker P, Sandvig K, and van Deurs B. Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells. Exp Cell Res 217: 157-168, 1995.
    • (1995) Exp Cell Res , vol.217 , pp. 157-168
    • Holm, P.K.1    Eker, P.2    Sandvig, K.3    Van Deurs, B.4
  • 18
    • 0035920227 scopus 로고    scopus 로고
    • + exchanger (NHE3) endocytosis via clathrin-coated vesicles: Dependence on protein kinase A-mediated NHE3 phosphorylation
    • + exchanger (NHE3) endocytosis via clathrin-coated vesicles: dependence on protein kinase A-mediated NHE3 phosphorylation. J Biol Chem 276: 26906-26915, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 26906-26915
    • Hu, M.C.1    Fan, L.2    Crowder, L.A.3    Karim-Jimenez, Z.4    Murer, H.5    Moe, O.W.6
  • 20
    • 0032491428 scopus 로고    scopus 로고
    • The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3
    • Lamprecht G, Weinman EJ, and Yun CH. The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3. J Biol Chem 273: 29972-29978, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 29972-29978
    • Lamprecht, G.1    Weinman, E.J.2    Yun, C.H.3
  • 23
    • 0029981094 scopus 로고    scopus 로고
    • A calcineurin homologous protein inhibits GTPase-stimulated Na/H exchange
    • Lin X and Barber DL. A calcineurin homologous protein inhibits GTPase-stimulated Na/H exchange. Proc Natl Acad Sci USA 93: 12631-12636, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12631-12636
    • Lin, X.1    Barber, D.L.2
  • 24
    • 0028169455 scopus 로고
    • 2+ sensitive phospholipid-binding protein with very high affinity for protein kinase C
    • 2+ sensitive phospholipid-binding protein with very high affinity for protein kinase C. J Biol Chem 269: 21043-21050, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 21043-21050
    • Liu, J.P.1    Powell, K.A.2    Sudhof, T.C.3    Robinson, P.J.4
  • 26
    • 0036201478 scopus 로고    scopus 로고
    • Endo- and exocytic rate constants for spontaneous and protein kinase C activation in cell receptor cycling
    • Menne C, Sorensen TM, Siersma V, von Essen M, Odum N, and Geisler C. Endo- and exocytic rate constants for spontaneous and protein kinase C activation in cell receptor cycling. Eur J Immunol 22: 616-626, 2002.
    • (2002) Eur J Immunol , vol.22 , pp. 616-626
    • Menne, C.1    Sorensen, T.M.2    Siersma, V.3    Von Essen, M.4    Odum, N.5    Geisler, C.6
  • 27
    • 0028927563 scopus 로고
    • Regulation of protein traffic in polarized epithelial cells
    • Mostov KE. Regulation of protein traffic in polarized epithelial cells. Histol Histopathol 10: 423-431, 1995.
    • (1995) Histol Histopathol , vol.10 , pp. 423-431
    • Mostov, K.E.1
  • 28
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function and regulation
    • Newton AC. Protein kinase C: structure, function and regulation. J Biol Chem 270: 28495-28498, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 31
    • 0034697319 scopus 로고    scopus 로고
    • Phosphorylation of dynamin I on Ser-795 by protein kinase C blocks its association with phospholipids
    • Powell KA, Valova VA, Malladi CS, Jensen ON, Larsen MR, and Robinson P. Phosphorylation of dynamin I on Ser-795 by protein kinase C blocks its association with phospholipids. J Biol Chem 275: 11610-11617, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 11610-11617
    • Powell, K.A.1    Valova, V.A.2    Malladi, C.S.3    Jensen, O.N.4    Larsen, M.R.5    Robinson, P.6
  • 34
    • 0032493929 scopus 로고    scopus 로고
    • Role of phosphorylation in regulation of the assembly of endocytic coat complexes
    • Slepnev VI, Ochoa GC, Butler MH, Grabs D, and De Camilli P. Role of phosphorylation in regulation of the assembly of endocytic coat complexes. Science 281: 821-824, 1998.
    • (1998) Science , vol.281 , pp. 821-824
    • Slepnev, V.I.1    Ochoa, G.C.2    Butler, M.H.3    Grabs, D.4    De Camilli, P.5
  • 35
    • 0000207414 scopus 로고    scopus 로고
    • Different protein kinase C isozymes mediate lower esophageal sphincter tone phasic contraction of esophageal circular smooth muscle
    • Sohn UD, Zoukhri D, Dartt D, Sergheraert C, Harnett KM, Behar J, and Biancani P. Different protein kinase C isozymes mediate lower esophageal sphincter tone phasic contraction of esophageal circular smooth muscle. Mol Pharmacol 51: 462-470, 1997.
    • (1997) Mol Pharmacol , vol.51 , pp. 462-470
    • Sohn, U.D.1    Zoukhri, D.2    Dartt, D.3    Sergheraert, C.4    Harnett, K.M.5    Behar, J.6    Biancani, P.7
  • 36
    • 0033385962 scopus 로고    scopus 로고
    • PKC-epsilon regulates basolateral endocytosis in human T84 intestinal epithelial of F-actin and MARCKS
    • Song JC, Hrnjez BJ, Farokhzad OC, and Matthews JB. PKC-epsilon regulates basolateral endocytosis in human T84 intestinal epithelial of F-actin and MARCKS. Am J Physiol Cell Physiol 277: C1239-C1249, 1999.
    • (1999) Am J Physiol Cell Physiol , vol.277
    • Song, J.C.1    Hrnjez, B.J.2    Farokhzad, O.C.3    Matthews, J.B.4
  • 37
    • 0032835198 scopus 로고    scopus 로고
    • Direct evidence of cytoplasmic delivery of PKC-alpha,-epsilon-zeta pseudosubstrate lipopeptides: Study of their implication in induction of apoptosis
    • Thiam K, Loing E, Zoukhri D, Rommens C, Hodges R, Dartt D, Verwaerde C, Auriault C, Gras-Masse H, and Sergheraert C. Direct evidence of cytoplasmic delivery of PKC-alpha,-epsilon-zeta pseudosubstrate lipopeptides: study of their implication in induction of apoptosis. FEBS Lett 459: 285-290, 1999.
    • (1999) FEBS Lett , vol.459 , pp. 285-290
    • Thiam, K.1    Loing, E.2    Zoukhri, D.3    Rommens, C.4    Hodges, R.5    Dartt, D.6    Verwaerde, C.7    Auriault, C.8    Gras-Masse, H.9    Sergheraert, C.10
  • 41
    • 0033864485 scopus 로고    scopus 로고
    • Protein kinase C isoenzymes: A review of their structure, regulation and role in regulating airways smooth muscle tone and mitogen
    • Webb BLJ, Hirst SJ, and Giembycz MA. Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogen. Br J Pharmacol 130: 1433-1452, 2000.
    • (2000) Br J Pharmacol , vol.130 , pp. 1433-1452
    • Webb, B.L.J.1    Hirst, S.J.2    Giembycz, M.A.3
  • 42
    • 0034705178 scopus 로고    scopus 로고
    • NHERF associations with sodium-hydrogen exchanger isoform (NHE3) and ezrin are essential for cAMP-mediated phosphorylation and inhibition of NHE3
    • Weinman EJ, Steplock D, Donowitz M, and Shenolikar S. NHERF associations with sodium-hydrogen exchanger isoform (NHE3) and ezrin are essential for cAMP-mediated phosphorylation and inhibition of NHE3. Biochemistry 39: 6123-6129, 2000.
    • (2000) Biochemistry , vol.39 , pp. 6123-6129
    • Weinman, E.J.1    Steplock, D.2    Donowitz, M.3    Shenolikar, S.4
  • 44
    • 0033021073 scopus 로고    scopus 로고
    • Acute regulation of Na/H exchanger NHE3 activity by protein kinase C: Role of phosphorylation
    • Wiederkekr MR, Zhao H, and Moe OW. Acute regulation of Na/H exchanger NHE3 activity by protein kinase C: role of phosphorylation. Am J Physiol Cell Physiol 276: C1205-C1217, 1999.
    • (1999) Am J Physiol Cell Physiol , vol.276
    • Wiederkekr, M.R.1    Zhao, H.2    Moe, O.W.3
  • 45
    • 0021971295 scopus 로고
    • Redistribution of phospholipid/calcium-dependent protein kinase and altered phosphorylation of its soluble and particulate substrate proteins in phorbol ester-treated rat pancreatic acini
    • Wooten MW and Wrenn RW. Redistribution of phospholipid/calcium-dependent protein kinase and altered phosphorylation of its soluble and particulate substrate proteins in phorbol ester-treated rat pancreatic acini. Cancer Res 45: 3912-3917, 1985.
    • (1985) Cancer Res , vol.45 , pp. 3912-3917
    • Wooten, M.W.1    Wrenn, R.W.2
  • 47
    • 0030738872 scopus 로고    scopus 로고
    • + exchanger isoform 3 stably expressed in fibroblasts by fibroblast growth factor and phorbol esters is not through changes in phosphorylation of the exchanger
    • + exchanger isoform 3 stably expressed in fibroblasts by fibroblast growth factor and phorbol esters is not through changes in phosphorylation of the exchanger. J Biol Chem 272: 18473-18480, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 18473-18480
    • Yip, J.W.1    Ko, W.H.2    Viberti, G.3    Huganir, R.L.4    Donowitz, M.5    Tse, C.M.6
  • 48
    • 0037040897 scopus 로고    scopus 로고
    • + exchanger isoform 3 revisited. The role of SGK1 and NHERF2
    • + exchanger isoform 3 revisited. The role of SGK1 and NHERF2. J Biol Chem 277: 7676-7683, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 7676-7683
    • Yun, C.C.1    Chen, Y.2    Lang, F.3
  • 49
    • 0032476006 scopus 로고    scopus 로고
    • NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border exchanger NHE3 and the cytoskeletal protein ezrin
    • Yun CH, Lamprecht G, Forster DV, and Sidor A. NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border exchanger NHE3 and the cytoskeletal protein ezrin. J Biol Chem 273: 25856-25863, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 25856-25863
    • Yun, C.H.1    Lamprecht, G.2    Forster, D.V.3    Sidor, A.4
  • 51
    • 0033548156 scopus 로고    scopus 로고
    • Acute inhibition of Na/H exchanger NHE3 by cAMP. Role of protein kinase NHE3 phosphoserines 552 and 605
    • Zhao H, Wiederkehr MR, Fan L, Collazo RL, Crowder LA, and Moe OW. Acute inhibition of Na/H exchanger NHE3 by cAMP. Role of protein kinase NHE3 phosphoserines 552 and 605. J Biol Chem 274: 3978-3987, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 3978-3987
    • Zhao, H.1    Wiederkehr, M.R.2    Fan, L.3    Collazo, R.L.4    Crowder, L.A.5    Moe, O.W.6
  • 53
    • 0031959120 scopus 로고    scopus 로고
    • Lacrimal gland functions are differentially controlled by protein kinase C isoforms
    • Zoukhri D, Hodges RR, Sergheraert C, and Dartt DA. Lacrimal gland functions are differentially controlled by protein kinase C isoforms. Ann NY Acad Sci 842: 217-220, 1998.
    • (1998) Ann NY Acad Sci , vol.842 , pp. 217-220
    • Zoukhri, D.1    Hodges, R.R.2    Sergheraert, C.3    Dartt, D.A.4
  • 54
    • 0031814977 scopus 로고    scopus 로고
    • Protein kinase C isoforms differentially control lacrimal gland functions
    • Zoukhri D, Hodges RR, Sergheraert C, and Dartt DA. Protein kinase C isoforms differentially control lacrimal gland functions. Adv Exp Med Biol 438: 181-186, 1998.
    • (1998) Adv Exp Med Biol , vol.438 , pp. 181-186
    • Zoukhri, D.1    Hodges, R.R.2    Sergheraert, C.3    Dartt, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.