Xylose and cellobiose fermentation to ethanol by the thermotolerant methylotrophic yeast Hansenula polymorpha

FEMS Yeast Research

Volumn 4, Issue 2 SPEC.ISS., 2003, Pages 157-164

  Ryabova, Olena B ^a   Chmil, Oksana M ^a   Sibirny, Andrii A ^a,b  

^a INSTITUTE OF CELL BIOLOGY   (Ukraine)

^b UNIVERSITY OF RZESZÓW   (Poland)

Author keywords

Cellobiose fermentation; Fuel ethanol; Hansenula polymorpha; High temperature alcoholic fermentation; Methylotrophic yeast; Riboflavin auxotrophy; Xylose fermentation

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; CARBON; CELLOBIOSE; GLUCOSE; RIBOFLAVIN; XYLOSE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FERMENTATION; HANSENULA POLYMORPHA; HEAT TOLERANCE; HIGH TEMPERATURE PROCEDURES; MUTANT; NONHUMAN; PICHIA STIPITIS; PRODUCTIVITY; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE; WILD TYPE; GENETIC ENGINEERING; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PICHIA;

HANSENULA POLYMORPHA; PICHIA ANGUSTA; PICHIA STIPITIS; SACCHAROMYCES CEREVISIAE;

CELLOBIOSE; ETHANOL; FERMENTATION; GENETIC ENGINEERING; GLUCOSE; PICHIA; RIBOFLAVIN; XYLOSE;

EID: 0242576754     PISSN: 15671356     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-1356(03)00146-6     Document Type: Article

References (34)

1. Wheals A.E. Basso L.C. Alves D.M.G. Amorim H.V. Fuel ethanol after 25 years Trends Biotechnol. 17 1999 482-486
2. Aristidou A. Penttilä M. Metabolic engineering applications to renewable resource utilization Curr. Opin. Biotechnol. 11 2000 187-198
3. Jeffries T.W. Jin Y.-S. Ethanol and thermotolerance in the bioconversion of xylose by yeasts Adv. Appl. Microbiol. 47 2000 221-268
4. Zaldivar J. Nielsen J. Olsson L. Fuel ethanol production from lignocellulose: a challenge for metabolic engineering and process integration Appl. Microbiol. Biotechnol. 56 2001 17-34
5. Banat I.M. Nigam P. Singh D. Marchant P. McHale A.P. Ethanol production at elevated temperatures and alcohol concentrations. Part I: Yeasts in general World J. Microbiol. Biotechnol. 14 1998 809-821
6. McMillan J.D. Newman M.M. Templeton D.W. Mohagheghi A. Simultaneous saccharification and cofermentation of dilute-acid pretreated yellow poplar hardwood to ethanol using xylose-fermenting Zymomonas mobilis Appl. Biochem. Biotechnol. 77/79 1999 649-655
7. du Preez J.C. Process parameters and environmental factors affecting D-xylose fermentation by yeasts Enzyme Microb. Technol. 16 1994 944-956
8. Jeffries T.W. Shi N.-Q. Genetic engineering for improved xylose fermentation by yeasts Adv. Biochem. Eng. Biotechnol. 65 1999 117-161
9. Kötter P. Ciriacy M. Xylose fermentation by Saccharomyces cerevisiae Appl. Microbiol. Biotechnol. 38 1993 776-783
10. Bao X. Gao D. Qu Y. Wang Z. Walfridson M. Hahn-Hägerdal B. Effect on product formation in recombinant Saccharomyces cerevisiae strains expressing different levels of xylose metabolic genes Chin. J. Biotechnol. 13 1997 225-231
11. Ho N.W.Y. Chen Z. Brainard A.P. Sedlak M. Successful design and development of genetically engineered Saccharomyces yeasts for effective cofermentation of glucose and xylose from cellulosic biomass to fuel ethanol Adv. Biochem. Eng. Biotechnol. 65 1999 163-192
12. Ryabova, O., Stelmashchuk, S., Maidan, M., Gonchar, M., Kotylak, Z., Grabek, D., Zaczek, A., Oklejewicz, B., Grzadka, M. and Sibirny, A. (2001) Glucose and xylose fermentation to ethanol or acetaldehyde using novel mutants of Hansenula polymorpha and Pichia stipitis. In: Abstracts 21st International Special Symposium on Yeasts: 'Biochemistry, Genetics, Biotechnology and Ecology of Non-conventional Yeasts', Lviv, Ukraine, 2001, p. 126.
13. Ryabova, O.B., Gonchar, M.V., Zaczek, A., Grabek, D., Sibirny, V.A., Kotylak, Z. and Sibirny, A.A. (2002) Xylose and glucose fermentation to ethanol and acetaldehyde by the thermotolerant yeast Hansenula polymorpha. In: Abstracts second Hansenula polymorpha Worldwide Network Conference, Tenerife, Spain, 2002, p.13.
14. Sibirny, A.A., Shavlovsky, G.M., Kshanovskaya, B.V. and Kutsiaba, V.I. (1982) Intraspecific and interspecific hybridization of yeasts by protoplast fusion (in Russian). In: Molekularnaya Biologiya Vol. 32, pp. 16-24. Naukova Dumka, Kiev.
15. 2 are non-essential for energy supply of yeast methylotrophic growth Arch. Microbiol. 154 1990 566-575
16. Sibirny A.A. Ksheminskaya G.P. Ubiyvovk V.M. Gonchar M.V. Bliznik K.M. Kapultsevich Y.G. The mutants of methylotrophic yeast Hansenula polymorpha defective in formaldehyde reductase (in Russian) Biotekhnologiya 5 1990 13-17
17. Shavlovsky G.M. Sibirny A.A. Kshanovskaya B.V. Koltun L.V. Logvinenko E.M. Genetic classification of the riboflavin deficient mutants of the yeast Pichia guilliermondii (in Russian) Genetika 15 1979 1561-1568
18. Voronovsky A.Y. Abbas C.A. Fayura L.R. Kshanovska B.V. Dmytruk K.V. Sybirna K.A. Sibirny A.A. Development of a transformation system for the flavinogenic yeast Candida famata FEMS Yeast Res. 2 2002 381-388
19. Gonchar M.V. Maidan M.M. Sibirny A.A. A new oxidase-peroxidase kit 'Alcotest' for ethanol assays in alcoholic beverages Food Technol. Biotechnol. 39 2001 37-42
20. Gonchar M.V. Sensitive method for quantitative determination of hydrogen peroxide and oxidase substrates in biological samples Ukr. Biochem. J. 70 1998 157-163
21. Somogyi M. Notes on sugar determination J. Biol. Chem. 195 1952 19-23
22. Singh D. Nigam P. Banat I.M. Marchant R. McHale A.P. Ethanol production at elevated temperatures and alcohol concentrations. Part II: Use of Kluyveromyces marxianus IMB3 World J. Microbiol. Biotechnol. 14 1998 823-834
23. Sibirny A.A. Titorenko V.I. Gonchar M.V. Ubiyvovk V.M. Ksheminskaya G.P. Vitvitskaya O.P. Genetic control of methanol utilization in yeasts J. Basic Microbiol. 28 1988 293-319
24. Gonchar M.V. Kostryk L.B. Sibirny A.A. Cytochrome c peroxidase from a methylotrophic yeast. Physiological role and isolation Appl. Microbiol. Biotechnol. 48 1997 454-458
25. 2-electrode sensors for alcohol assays based on the use of permeabilized mutant cells as the sensitive bioelements Biosens. Bioelectron. 13 1998 945-952
26. Moroz O.M. Gonchar M.V. Sibirny A.A. Efficient bioconversion of ethanol to acetaldehyde using a novel mutant strain of the methylotrophic yeast Hansenula polymorpha Biotechnol. Bioeng. 68 2000 44-51
27. Ubiyvovk V.M. Nazarko T.Y. Stasyk O.G. Sohn M.J. Kang H.A. Sibirny A.A. GSH2, a gene encoding γ-glutamylcysteine synthetase in the methylotrophic yeast Hansenula polymorpha FEMS Yeast Res. 2 2002 327-332
28. Sahm H. Metabolism of methanol by yeasts Adv. Biochem. Eng. 6 1977 77-103
29. Hansen, H. and Hollenberg, C.P. (1996) Hansenula polymorpha (Pichia angusta). In: Nonconventional Yeasts in Biotechnology (Wolf, K., Ed.), pp. 293-311. Springer, Berlin.
30. van Dijken J.P. Harder W. Beardsmore A.J. Quayle R.R. Dihydroxyacetone: an intermediate in the assimilation of methanol by yeasts? FEMS Microbiol. Lett. 4 1978 97-102
31. Barnett, J.A., Payne, R.W. and Yarrow, D. (1990) Yeasts. Characteristics and Identification, 2nd Edn. Cambridge University Press, Cambridge.
32. Shi N.Q. Davis B. Sherman F. Cruz J. Jeffries T.W. Disruption of the cytochrome c gene in xylose-utilizing yeast Pichia stipitis leads to higher ethanol production Yeast 15 1999 1021-1030
33. Gellissen G. Piontek M. Dahlems U. Jenzelewski V. Gavagan J.E. DiCosimo R. Andton D.L. Janowicz Z.A. Recombinant Hansenula polymorpha as a biocatalyst: coexpression of the spinach glycolate oxidase (GO) and the S. cerevisiae catalase T (CTT1) gene Appl. Microbiol. Biotechnol. 46 1996 46-54
34. Sohn J.H. Choi E.S. Kang H.A. Rhee J.S. Agaphonov M.O. Ter-Avanesyan M.D. Rhee S.K. A dominant selection system designed for copy-number-controlled gene integration in Hansenula polymorpha DL1 Appl. Microbiol. Biotechnol. 51 1999 800-807