Regulatory region variability in the human presenilin-2 (PSEN2) gene: Potential contribution to the gene activity and risk for AD

Molecular Psychiatry

Volumn 7, Issue 8, 2002, Pages 891-898

  Riazanskaia, N ^a   Lukiw, W J ^b,c   Grigorenko, A ^a,d   Korovaitseva, G ^a   Dvoryanchikov, G ^a   Moliaka, Y ^a   Nicolaou, M ^e   Farrer, L ^e,f   Bazan, N G ^b,c   Rogaev, Evgeny I ^a  

^a MENTAL HEALTH RESEARCH CENTER   (Russian Federation)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d INSTITUTE OF MOLECULAR GENETICS   (Russian Federation)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Alzheimer's disease; Genetic association; Polymorphism; Presenilin; Promoter; Transcription factors

Indexed keywords

AMYLOID BETA PROTEIN; INTERFERON REGULATORY FACTOR 2; INTERLEUKIN 1BETA; PRESENILIN 2; TRANSCRIPTION FACTOR;

ALZHEIMER DISEASE; ARTICLE; DNA SEQUENCE; GENE ACTIVITY; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; INFLAMMATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; REGRESSION ANALYSIS; REGULATOR GENE; REPORTER GENE; SEQUENCE ANALYSIS;

5' UNTRANSLATED REGIONS; AGED; ALZHEIMER DISEASE; CELLS, CULTURED; DNA MUTATIONAL ANALYSIS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENES, REPORTER; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUCIFERASES; MEMBRANE PROTEINS; MIDDLE AGED; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; PRESENILIN-2; PROMOTER REGIONS (GENETICS); RISK FACTORS; STEM CELLS; TRANSCRIPTION FACTORS; VARIATION (GENETICS);

EID: 0036385788     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001101     Document Type: Article

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