메뉴 건너뛰기




Volumn 170, Issue 2, 2003, Pages 215-224

Evaluation of the phencyclidine-like discriminative stimulus effects of novel NMDA channel blockers in rats

Author keywords

Drug discrimination; NMDA receptor antagonists; Phencyclidine; Rats; Side effects

Indexed keywords

1 (4 METHOXYPHENYL) 1,2,3,4 TETRAHYDROISOQUINOLINE; 1 METHYL 1 PHENYL 1,2,3,4 TETRAHYDROISOQUINOLINE; 1 PHENYL 1,2,3,4 TETRAHYDROISOQUINOLINE; 8 (2 METHOXYPHENYL) 1,2,3,4 TETRAHYDROISOQUINOLINE; ALAPROCLATE; ANTAZOLINE; FR 115427; IDAZOXAN; N METHYL 1,3 DIPHENYLISOPROPYLAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NERAMEXANE; ORPHENADRINE; PD 137889; PD 138289; PHENCYCLIDINE; UNCLASSIFIED DRUG;

EID: 0242492184     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1527-6     Document Type: Article
Times cited : (14)

References (68)
  • 1
    • 0024381934 scopus 로고
    • Substitution and antagonism in rats trained to discriminate (+)-N-allylnormetazocine from saline
    • Balster RL (1989) Substitution and antagonism in rats trained to discriminate (+)-N-allylnormetazocine from saline. J Pharmacol Ther 249:749-756
    • (1989) J Pharmacol Ther , vol.249 , pp. 749-756
    • Balster, R.L.1
  • 2
    • 0026388927 scopus 로고
    • Discriminative stimulus properties of phencyclidine and other NMDA antagonists
    • Glennon RA, Järbe TUC, Frankenheim J (eds) Drug discrimination: applications to drug abuse research. DHHS Publication No. ADXM 92-1878. U.S. Government Printing Office, Washington
    • Balster RL (1991a) Discriminative stimulus properties of phencyclidine and other NMDA antagonists. In: Glennon RA, Järbe TUC, Frankenheim J (eds) Drug discrimination: applications to drug abuse research. National Institute on Drug Abuse Research Monograph Series 116, DHHS Publication No. ADXM 92-1878. U.S. Government Printing Office, Washington, pp 163-180
    • (1991) National Institute on Drug Abuse Research Monograph Series , vol.116 , pp. 163-180
    • Balster, R.L.1
  • 3
    • 0009719763 scopus 로고
    • Drug abuse potential evaluation in animals
    • Balster RL (1991b) Drug abuse potential evaluation in animals. Br J Addict 86:549-1558
    • (1991) Br J Addict , vol.86 , pp. 549-1558
    • Balster, R.L.1
  • 5
    • 0025236764 scopus 로고
    • The self-administration of MK-801 can depend upon drug-reinforcement history and its discriminative stimulus properties are phencyclidine-like in rhesus monkeys
    • Beardsley PM, Hayes BA, Balster RL (1990) The self-administration of MK-801 can depend upon drug-reinforcement history and its discriminative stimulus properties are phencyclidine-like in rhesus monkeys. J Pharmacol Ther 252:953-959
    • (1990) J Pharmacol Ther , vol.252 , pp. 953-959
    • Beardsley, P.M.1    Hayes, B.A.2    Balster, R.L.3
  • 9
    • 0020086084 scopus 로고
    • Stereoisomers of N-allylnormetazocine: Phencyclidine-like behavioral effects in squirrel monkeys and rats
    • Brady KT, Balster RL, May EL (1982a) Stereoisomers of N-allylnormetazocine: phencyclidine-like behavioral effects in squirrel monkeys and rats. Science 215:178-180
    • (1982) Science , vol.215 , pp. 178-180
    • Brady, K.T.1    Balster, R.L.2    May, E.L.3
  • 10
    • 0020077026 scopus 로고
    • Discriminative stimulus and reinforcing properties of etoxadrol and dexoxadrol in monkeys
    • Brady KT, Woolverton WL, Balster RL (1982b) Discriminative stimulus and reinforcing properties of etoxadrol and dexoxadrol in monkeys. J Pharmacol Exp Ther 220:56-62
    • (1982) J Pharmacol Exp Ther , vol.220 , pp. 56-62
    • Brady, K.T.1    Woolverton, W.L.2    Balster, R.L.3
  • 11
    • 0242666551 scopus 로고
    • Treatment of paralysis agitans with orphenadrine (Disipal). Results in 176 cases
    • Doshay LJ, Constable K (1957) Treatment of paralysis agitans with orphenadrine (Disipal). Results in 176 cases. J Am Med Assoc 163:1352-1357
    • (1957) J Am Med Assoc , vol.163 , pp. 1352-1357
    • Doshay, L.J.1    Constable, K.2
  • 12
    • 0242414875 scopus 로고
    • Clinical trial of orphenadrine in skeletal muscle disorders
    • Finch JW (1959) Clinical trial of orphenadrine in skeletal muscle disorders. Clin Med Surg 6:195-198
    • (1959) Clin Med Surg , vol.6 , pp. 195-198
    • Finch, J.W.1
  • 14
    • 0032882035 scopus 로고    scopus 로고
    • Behavioral effects and anticonvulsant efficacies of low-affinity, uncompetitive NMDA antagonists in mice
    • Geter-Douglass B, Witkin JM (1999) Behavioral effects and anticonvulsant efficacies of low-affinity, uncompetitive NMDA antagonists in mice. Psychopharmacology 146:280-289
    • (1999) Psychopharmacology , vol.146 , pp. 280-289
    • Geter-Douglass, B.1    Witkin, J.M.2
  • 15
    • 0030483729 scopus 로고    scopus 로고
    • Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists
    • Grant KA, Colombo G, Grant J, Rogawski MA (1996) Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists. Neuropharmacology 35:1709-1719
    • (1996) Neuropharmacology , vol.35 , pp. 1709-1719
    • Grant, K.A.1    Colombo, G.2    Grant, J.3    Rogawski, M.A.4
  • 16
    • 0024328330 scopus 로고
    • Phencyclidine-like effects of tetrahydroisoquinolines and related compounds
    • Gray NM, Cheng BK, Mick SJ, Lair CM, Contrereas PC (1989) Phencyclidine-like effects of tetrahydroisoquinolines and related compounds. J Med Chem 32:1242-1248
    • (1989) J Med Chem , vol.32 , pp. 1242-1248
    • Gray, N.M.1    Cheng, B.K.2    Mick, S.J.3    Lair, C.M.4    Contrereas, P.C.5
  • 18
    • 0031897446 scopus 로고    scopus 로고
    • The role of N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission in the pathophysiology and therapeutics of psychiatric syndromes
    • Heresco-Levy U, Javitt DC (1998) The role of N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission in the pathophysiology and therapeutics of psychiatric syndromes. Eur Neuropsychopharmacol 8:141-152
    • (1998) Eur Neuropsychopharmacol , vol.8 , pp. 141-152
    • Heresco-Levy, U.1    Javitt, D.C.2
  • 19
    • 0032850730 scopus 로고    scopus 로고
    • Brain distribution of an uncompetitive NMDA receptor antagonist: Comparison to its in vitro potency in electrophysiological studies
    • Hesselink MB, Parsons CG, Wollenburg C, Danysz W (1999) Brain distribution of an uncompetitive NMDA receptor antagonist: comparison to its in vitro potency in electrophysiological studies. Naunyn Schmiedebergs Arch Pharmacol 360:144-550
    • (1999) Naunyn Schmiedebergs Arch Pharmacol , vol.360 , pp. 144-550
    • Hesselink, M.B.1    Parsons, C.G.2    Wollenburg, C.3    Danysz, W.4
  • 20
    • 0242414917 scopus 로고
    • Orphenadrine citrate in the treatment of muscular pain
    • Hoddes SH (1964) Orphenadrine citrate in the treatment of muscular pain. Practitioner 193:76-80
    • (1964) Practitioner , vol.193 , pp. 76-80
    • Hoddes, S.H.1
  • 22
    • 0001072453 scopus 로고
    • Discriminative stimulus effects of drugs: Relationship to potential for abuse
    • Adler MA, Cowan A (eds). Wiley-Liss, New York
    • Holtzman SG (1990) Discriminative stimulus effects of drugs: relationship to potential for abuse. In: Adler MA, Cowan A (eds) Testing and evaluation of drugs of abuse. Wiley-Liss, New York, pp 193-210
    • (1990) Testing and Evaluation of Drugs of Abuse , pp. 193-210
    • Holtzman, S.G.1
  • 23
    • 0031054784 scopus 로고    scopus 로고
    • NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857
    • Hu P-S, Ross SB (1997) NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857. Pharmacol Tox 80:97-102
    • (1997) Pharmacol Tox , vol.80 , pp. 97-102
    • Hu, P.-S.1    Ross, S.B.2
  • 24
    • 0025806856 scopus 로고
    • Clinical and pharmacological review of the efficacy of orphenadrine and its combination with paracetamol in painful conditions
    • Hunskaar S, Donnell D (1991) Clinical and pharmacological review of the efficacy of orphenadrine and its combination with paracetamol in painful conditions. J Int Med Res 19:71-87
    • (1991) J Int Med Res , vol.19 , pp. 71-87
    • Hunskaar, S.1    Donnell, D.2
  • 25
    • 0023808784 scopus 로고
    • Is the discriminative stimulus produced by phencyclidine due to an interaction with N-methyl-D-aspartate receptors?
    • Jackson A, Sanger DJ (1988) Is the discriminative stimulus produced by phencyclidine due to an interaction with N-methyl-D-aspartate receptors? Psychopharmacology 96:87-92
    • (1988) Psychopharmacology , vol.96 , pp. 87-92
    • Jackson, A.1    Sanger, D.J.2
  • 26
    • 0032005724 scopus 로고    scopus 로고
    • Failure of ibogaine to produce phencyclidine-like discriminative stimulus effects in rats and monkeys
    • Jones HE, Li H, Balster RL (1998) Failure of ibogaine to produce phencyclidine-like discriminative stimulus effects in rats and monkeys. Pharmacol Biochem Behav 59:413-418
    • (1998) Pharmacol Biochem Behav , vol.59 , pp. 413-418
    • Jones, H.E.1    Li, H.2    Balster, R.L.3
  • 28
    • 0028836150 scopus 로고
    • The neuroprotective effect of the novel noncompetitive NMDA antagonist, FR 115427 in focal cerebral ischemia in rats
    • Katsuta K, Nakanishi H, Shirakawa K, Yoshida K, Takagi K, Tamura A (1995) The neuroprotective effect of the novel noncompetitive NMDA antagonist, FR 115427 in focal cerebral ischemia in rats. J Cereb Blood Flow Metab 15:345-348
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 345-348
    • Katsuta, K.1    Nakanishi, H.2    Shirakawa, K.3    Yoshida, K.4    Takagi, K.5    Tamura, A.6
  • 29
    • 0031934530 scopus 로고    scopus 로고
    • Discriminative stimulus effects of 8-hydroxy-2-(di-n-propylamino) tetralin in pigeons and rats: Species similarities and differences
    • Kleven MS, Koek W (1998) Discriminative stimulus effects of 8-hydroxy-2-(di-n-propylamino)tetralin in pigeons and rats: species similarities and differences. J Pharmacol Exp Ther 284:238-249
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 238-249
    • Kleven, M.S.1    Koek, W.2
  • 30
    • 0021643628 scopus 로고
    • Effects of histamine and H1- And H2-receptor antagonists on wet-dog-shake episodes in rats induced with tranylcypromine and 5-methoxytryptamine
    • Kolasa K, Kleinrok Z, Rajtar G, Juszkiewicz M (1984) Effects of histamine and H1-and H2-receptor antagonists on wet-dog-shake episodes in rats induced with tranylcypromine and 5-methoxytryptamine. Acta Physiol Pol 35:225-230
    • (1984) Acta Physiol Pol , vol.35 , pp. 225-230
    • Kolasa, K.1    Kleinrok, Z.2    Rajtar, G.3    Juszkiewicz, M.4
  • 31
    • 0029417266 scopus 로고
    • Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: Binding and patch clamp studies
    • Kornhuber J, Parsons CG, Hartmann S, Retz W, Kamolz S, Thome J, Riederer P (1995) Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies. J Neural Trans 102:237-246
    • (1995) J Neural Trans , vol.102 , pp. 237-246
    • Kornhuber, J.1    Parsons, C.G.2    Hartmann, S.3    Retz, W.4    Kamolz, S.5    Thome, J.6    Riederer, P.7
  • 33
    • 0018191185 scopus 로고
    • Inhibitors of neuronal monoamine uptake. 2. Selective inhibition of 5-hydroxytryptamine uptake by alpha-amino acid esters of phenethyl alcohols
    • Lindberg UH, Thorberg SO, Bengtsson S, Renyi AL, Ross SB, Ogren SO (1978) Inhibitors of neuronal monoamine uptake. 2. Selective inhibition of 5-hydroxytryptamine uptake by alpha-amino acid esters of phenethyl alcohols. J Med Chem 21:448-456
    • (1978) J Med Chem , vol.21 , pp. 448-456
    • Lindberg, U.H.1    Thorberg, S.O.2    Bengtsson, S.3    Renyi, A.L.4    Ross, S.B.5    Ogren, S.O.6
  • 34
    • 0034678533 scopus 로고    scopus 로고
    • MRZ 2/579, a novel uncompetitive N-methyl-D-aspartate antagonist, reduces infarct volume and brain swelling and improves neurological deficit after focal cerebral ischemia in rats
    • Liu Y, Belayev L, Zhao W, Busto R, Ginsberg MD (2000) MRZ 2/579, a novel uncompetitive N-methyl-D-aspartate antagonist, reduces infarct volume and brain swelling and improves neurological deficit after focal cerebral ischemia in rats. Brain Res 862:111-119
    • (2000) Brain Res , vol.862 , pp. 111-119
    • Liu, Y.1    Belayev, L.2    Zhao, W.3    Busto, R.4    Ginsberg, M.D.5
  • 35
    • 0031850091 scopus 로고    scopus 로고
    • Drug discrimination studies of the interoceptive cues produced by selective serotonin uptake inhibitors and selective serotonin releasing agents
    • Marona-Lewicka D, Nichols DE (1998) Drug discrimination studies of the interoceptive cues produced by selective serotonin uptake inhibitors and selective serotonin releasing agents. Psychopharmacology 138:67-75
    • (1998) Psychopharmacology , vol.138 , pp. 67-75
    • Marona-Lewicka, D.1    Nichols, D.E.2
  • 36
    • 0034925001 scopus 로고    scopus 로고
    • S33005, a novel ligand at both serotonin and norepinephrine transporters. II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine
    • Millan MJ, Dekeyne A, Papp M, La Rochelle CD, MacSweeny C, Peglion J-L, Brocco M (2001) S33005, a novel ligand at both serotonin and norepinephrine transporters. II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine. J Pharmacol Exp Ther 298:581-591
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 581-591
    • Millan, M.J.1    Dekeyne, A.2    Papp, M.3    La Rochelle, C.D.4    MacSweeny, C.5    Peglion, J.-L.6    Brocco, M.7
  • 37
    • 0015421882 scopus 로고
    • Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism
    • Mindham RHS, Gaind R, Anstee BH, Rimmer L (1972) Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism. Psychol Med 2:406-413
    • (1972) Psychol Med , vol.2 , pp. 406-413
    • Mindham, R.H.S.1    Gaind, R.2    Anstee, B.H.3    Rimmer, L.4
  • 38
    • 0029079769 scopus 로고
    • α-Benzyl-N-methylphenethylamine (BNMPA), an impurity of illicit methamphetamine synthesis: Pharmacological evaluation and interaction with methamphetamine
    • Moore KA, Lichtman AH, Poklis A, Borzelleca JF (1995) α-Benzyl-N-methylphenethylamine (BNMPA), an impurity of illicit methamphetamine synthesis: pharmacological evaluation and interaction with methamphetamine. Drug Alcohol Depend 39:83-89
    • (1995) Drug Alcohol Depend , vol.39 , pp. 83-89
    • Moore, K.A.1    Lichtman, A.H.2    Poklis, A.3    Borzelleca, J.F.4
  • 39
    • 17544386280 scopus 로고    scopus 로고
    • Pharmacological characterization of BNMPA (α-benzyl-N- methylphenethylamine), an impurity of illicit methamphetamine synthesis
    • Moore KA, Mirshahi T, Compton DR, Poklis A, Woodward JJ (1996) Pharmacological characterization of BNMPA (α-benzyl-N- methylphenethylamine), an impurity of illicit methamphetamine synthesis. Eur J Pharmacol 311:133-139
    • (1996) Eur J Pharmacol , vol.311 , pp. 133-139
    • Moore, K.A.1    Mirshahi, T.2    Compton, D.R.3    Poklis, A.4    Woodward, J.J.5
  • 41
    • 0031779010 scopus 로고    scopus 로고
    • Evaluation of the reinforcing and discriminative stimulus properties of the low-affinity N-methyl-D-aspartate channel blocker memantine
    • Nicholson KL, Jones HE, Balster RL (1998) Evaluation of the reinforcing and discriminative stimulus properties of the low-affinity N-methyl-D-aspartate channel blocker memantine. Behav Pharmacol 9:231-243
    • (1998) Behav Pharmacol , vol.9 , pp. 231-243
    • Nicholson, K.L.1    Jones, H.E.2    Balster, R.L.3
  • 42
    • 0032822457 scopus 로고    scopus 로고
    • Evaluation of the reinforcing properties and phencyclidine-like discriminative stimulus effects of dextromethorphan and dextrorphan in rats and rhesus monkeys
    • Nicholson KL, Hayes BA, Balster RL (1999) Evaluation of the reinforcing properties and phencyclidine-like discriminative stimulus effects of dextromethorphan and dextrorphan in rats and rhesus monkeys. Psychopharmacology 146:49-59
    • (1999) Psychopharmacology , vol.146 , pp. 49-59
    • Nicholson, K.L.1    Hayes, B.A.2    Balster, R.L.3
  • 43
    • 0026717307 scopus 로고
    • The suppression of olfactory bulbectomy-induced muricide by antidepressants and antihistamines via histamine H1 receptor blocking
    • Noguchi S, Inukai T, Kuno T, Tanaka C (1992) The suppression of olfactory bulbectomy-induced muricide by antidepressants and antihistamines via histamine H1 receptor blocking. Physiol Behav 51:1123-1127
    • (1992) Physiol Behav , vol.51 , pp. 1123-1127
    • Noguchi, S.1    Inukai, T.2    Kuno, T.3    Tanaka, C.4
  • 45
    • 0030605955 scopus 로고    scopus 로고
    • Imidazoli(di)ne compounds interact with the phencyclidine site of NMDA receptors in the rat brain
    • Olmos G, Ribera J, Garcia-Sevilla JA (1996) Imidazoli(di)ne compounds interact with the phencyclidine site of NMDA receptors in the rat brain. Eur J Pharmacol 310:273-276
    • (1996) Eur J Pharmacol , vol.310 , pp. 273-276
    • Olmos, G.1    Ribera, J.2    Garcia-Sevilla, J.A.3
  • 46
    • 0034852744 scopus 로고    scopus 로고
    • Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies
    • Palmer GC (2001) Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies. Curr Drug Targets 2:241-271
    • (2001) Curr Drug Targets , vol.2 , pp. 241-271
    • Palmer, G.C.1
  • 47
    • 0028885626 scopus 로고
    • Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo
    • Parsons CG, Quack G, Bresink I, Baran L, Przegalinski E, Kostowski W, Krzascik P, Hartmann S, Danysz W (1995) Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo. Neuropharmacology 34:1239-1258
    • (1995) Neuropharmacology , vol.34 , pp. 1239-1258
    • Parsons, C.G.1    Quack, G.2    Bresink, I.3    Baran, L.4    Przegalinski, E.5    Kostowski, W.6    Krzascik, P.7    Hartmann, S.8    Danysz, W.9
  • 48
    • 0032467053 scopus 로고    scopus 로고
    • Glutamate in CNS disorders as a target for drug development?
    • Parsons CG, Danysz W, Quack G (1998) Glutamate in CNS disorders as a target for drug development? Drug News Perspect 11:523-569
    • (1998) Drug News Perspect , vol.11 , pp. 523-569
    • Parsons, C.G.1    Danysz, W.2    Quack, G.3
  • 49
    • 0032968779 scopus 로고    scopus 로고
    • Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: In vitro and in vivo characterization
    • Parsons CG, Danysz W, Bartmann A, Spielmanns P, Frankiewicz T, Hesselink M, Eilbacher B, Quack G (1999) Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo characterization. Neuropharmacology 38:85-108
    • (1999) Neuropharmacology , vol.38 , pp. 85-108
    • Parsons, C.G.1    Danysz, W.2    Bartmann, A.3    Spielmanns, P.4    Frankiewicz, T.5    Hesselink, M.6    Eilbacher, B.7    Quack, G.8
  • 50
    • 0033806040 scopus 로고    scopus 로고
    • Memantine and the amino-alkyl-cyclohexane MRZ 2/579 are moderate affinity uncompetitive NMDA receptor antagonists - In vitro characterisation
    • Parsons CG, Danysz W, Quack G (2000) Memantine and the amino-alkyl-cyclohexane MRZ 2/579 are moderate affinity uncompetitive NMDA receptor antagonists - in vitro characterisation. Amino Acids 19:157-166
    • (2000) Amino Acids , vol.19 , pp. 157-166
    • Parsons, C.G.1    Danysz, W.2    Quack, G.3
  • 51
    • 0034098620 scopus 로고    scopus 로고
    • Clinically available NMDA receptor antagonists memantine and dextromethorphan reverse existing tolerance to the antinociceptive effects of morphine in mice
    • Popik P, Kozela E, Danysz W (2000) Clinically available NMDA receptor antagonists memantine and dextromethorphan reverse existing tolerance to the antinociceptive effects of morphine in mice. Naunyn Schmiedebergs Arch Pharmacol 361:425-432
    • (2000) Naunyn Schmiedebergs Arch Pharmacol , vol.361 , pp. 425-432
    • Popik, P.1    Kozela, E.2    Danysz, W.3
  • 52
    • 0027176541 scopus 로고
    • Therapeutic potential of excitatory amino acid antagonists: Channel blockers and 2,3-benzodiazepines
    • Rogawski MA (1993) Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines. Trends Pharmacol Sci 14:325-331
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 325-331
    • Rogawski, M.A.1
  • 53
    • 0024340712 scopus 로고
    • Discriminative stimulus effects of the alpha 2-adrenoceptor antagonist idazoxan
    • Sanger DJ (1989) Discriminative stimulus effects of the alpha 2-adrenoceptor antagonist idazoxan. Psychopharmacology 99:117-121
    • (1989) Psychopharmacology , vol.99 , pp. 117-121
    • Sanger, D.J.1
  • 54
    • 0026767797 scopus 로고
    • Memantine has phencyclidine-like but not cocaine-like discriminative stimulus effects in rats
    • Sanger DJ, Terry P, Katz JL (1992) Memantine has phencyclidine-like but not cocaine-like discriminative stimulus effects in rats. Behav Pharmacol 3:265-268
    • (1992) Behav Pharmacol , vol.3 , pp. 265-268
    • Sanger, D.J.1    Terry, P.2    Katz, J.L.3
  • 55
    • 0028067244 scopus 로고
    • Ethanol drug discrimination in rats: Substitution with GABA agonists and NMDA antagonists
    • Shelton KL, Balster RL (1994) Ethanol drug discrimination in rats: substitution with GABA agonists and NMDA antagonists. Behav Pharmacol 5:441-451
    • (1994) Behav Pharmacol , vol.5 , pp. 441-451
    • Shelton, K.L.1    Balster, R.L.2
  • 57
    • 0021553607 scopus 로고
    • Phencyclidine-like discriminative stimulus properties of the stereoisomers of dioxadrol
    • Slifer BL, Balster RL (1985) Phencyclidine-like discriminative stimulus properties of the stereoisomers of dioxadrol. Subst Alcohol Actions Misuse 5:273-280
    • (1985) Subst Alcohol Actions Misuse , vol.5 , pp. 273-280
    • Slifer, B.L.1    Balster, R.L.2
  • 58
    • 0034071804 scopus 로고    scopus 로고
    • Effects of the NMDA receptor channel blockers memantine and MRZ 2/579 on morphine withdrawal-facilitated aggression in mice
    • Sukhotina IA, Bespalov AY (2000) Effects of the NMDA receptor channel blockers memantine and MRZ 2/579 on morphine withdrawal-facilitated aggression in mice. Psychopharmacology 149:345-350
    • (2000) Psychopharmacology , vol.149 , pp. 345-350
    • Sukhotina, I.A.1    Bespalov, A.Y.2
  • 60
    • 0028307264 scopus 로고
    • Alaproclate effects on voltage-dependent K+ channels and NMDA receptors: Studies in cultured rat hippocampal neurons and fibroblast cells transformed with Kv1.2 K+ channel cDNA
    • Svensson BE, Werkman TR, Rogawski MA (1994) Alaproclate effects on voltage-dependent K+ channels and NMDA receptors: studies in cultured rat hippocampal neurons and fibroblast cells transformed with Kv1.2 K+ channel cDNA. Neuropharmacology 33:795-804
    • (1994) Neuropharmacology , vol.33 , pp. 795-804
    • Svensson, B.E.1    Werkman, T.R.2    Rogawski, M.A.3
  • 61
    • 0023831051 scopus 로고
    • Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung
    • Syvälahti EK, Kunelius R, Lauren L (1988) Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung. Pharmacol Toxicol 62:90-94
    • (1988) Pharmacol Toxicol , vol.62 , pp. 90-94
    • Syvälahti, E.K.1    Kunelius, R.2    Lauren, L.3
  • 62
  • 64
    • 0024230487 scopus 로고
    • The discriminative stimulus effects of N-methyl-D-aspartate antagonists in phencyclidine-trained rats
    • Willetts J, Balster RL (1988a) The discriminative stimulus effects of N-methyl-D-aspartate antagonists in phencyclidine-trained rats. Neuropharmacology 27:1249-1256
    • (1988) Neuropharmacology , vol.27 , pp. 1249-1256
    • Willetts, J.1    Balster, R.L.2
  • 65
    • 0023874510 scopus 로고
    • Phencyclidine-like discriminative stimulus properties of MK-801 in rats
    • Willetts J, Balster RL (1988b) Phencyclidine-like discriminative stimulus properties of MK-801 in rats. Eur J Pharmacol 146:167-169
    • (1988) Eur J Pharmacol , vol.146 , pp. 167-169
    • Willetts, J.1    Balster, R.L.2
  • 66
    • 0032906982 scopus 로고    scopus 로고
    • Anticonvulsant efficacy of N-methyl-D-aspartate antagonists against convulsions induced by cocaine
    • Witkin JM, Gasior M, Heifets B, Tortella FC (1999) Anticonvulsant efficacy of N-methyl-D-aspartate antagonists against convulsions induced by cocaine. J Pharmacol Exp Ther 289:703-711
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 703-711
    • Witkin, J.M.1    Gasior, M.2    Heifets, B.3    Tortella, F.C.4
  • 67
    • 0027137403 scopus 로고
    • Dose-dependent discriminative stimulus properties of 8-OH-DPAT
    • Ybema CE, Slangen JL, Olivier B, Mos J (1993) Dose-dependent discriminative stimulus properties of 8-OH-DPAT. Behav Pharmacol 4:610-624
    • (1993) Behav Pharmacol , vol.4 , pp. 610-624
    • Ybema, C.E.1    Slangen, J.L.2    Olivier, B.3    Mos, J.4
  • 68
    • 0030042201 scopus 로고    scopus 로고
    • Infusion of (+)-MK-801 and memantine - Contrasting effects on radial maze learning in rats with entorhinal cortex lesion
    • Zajaczkowski W, Quack G, Danysz W (1996) Infusion of (+)-MK-801 and memantine - contrasting effects on radial maze learning in rats with entorhinal cortex lesion. Eur J Pharmacol 296:239-246
    • (1996) Eur J Pharmacol , vol.296 , pp. 239-246
    • Zajaczkowski, W.1    Quack, G.2    Danysz, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.