Essential role for the homeoprotein vHNF1/HNF1β in visceral endoderm differentiation

Development

Volumn 126, Issue 21, 1999, Pages 4785-4794

  Coffinier, Catherine ^a   Thépot, Dominique ^a,c   Babinet, Charles ^b   Yaniv, Moshe ^a   Barra, Jacqueline ^b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c CEMAGREF   (France)

Author keywords

Embryonic lethality; Gene knock out; Homeoprotein; Tetraploid rescue; Visceral endoderm

Indexed keywords

HOMEODOMAIN PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; GENE INACTIVATION; GENETIC COMPLEMENTATION; LETHAL MUTANT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DIFFERENTIATION; VISCERA;

ABNORMALITIES, MULTIPLE; ANIMALS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; EMBRYO; ENDODERM; FETAL DEATH; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HEPATOCYTE NUCLEAR FACTOR 1-BETA; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; NUCLEAR PROTEINS; POLYPLOIDY; RABBITS; TRANSCRIPTION FACTORS; VISCERA;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0344771681     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Abe, K., Niwa, H., Iwase, K., Takiguchi, M., Mori, M., Abe, S. I., Abe, K. and Yamamura, K. I. (1996). Endoderm-specific gene expression in embryonic stem cells differentiated to embryoid bodies. Exp. Cell Res. 229, 27-34.
2. Ang, S. L. and Rossant, J. (1994). HNF-3 beta is essential for node and notochord formation in mouse development. Cell 78, 561-574.
3. Beddington, R. S. and Robertson, E. J. (1998). Anterior patterning in mouse. Trench Genet. 14, 277-284.
4. Blumenfeld, M., Maury, M., Chouard, T., Yaniv, M. and Condamine, H. (1991). Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse. Development 113, 589-599.
5. Cereghini, S., Ott, M. O., Power, S. and Maury, M. (1992). Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplanlation embryos suggest distinct and sequential developmental roles. Development 116, 783-797.
6. Chen, W. S., Manova, K., Weinstein, D. C., Duncan, S. A., Plump, A. S., Prezioso, V. R., Bachvarova, R. F. and Darnell, J. E. J. (1994). Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev. 8, 2466-2477.
7. Copp, A. J. (1995). Death before birth: clues from gene knockouts and mutations. Trends Genet. 11, 87-93.
8. Demartis, A., Maffei, M., Vignali, R., Barsacchi, G. and De Simone, V. (1994). Cloning and developmental expression of LFB3/HNF1 beta transcription factor in Xenopus laevis. Mech. Dev. 47, 19-28.
9. Deng, C. X., Wynshaw-Boris, A., Shen, M. M., Daugherty, C., Ornitz, D. M. and Leder, P. (1994). Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 8, 3045-3057.
10. Dufort, D., Schwartz, L., Harpal, K. and Rossant, J. (1998). The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development 125, 3015-3025.
11. Duncan, S. A., Manova, K., Chen, W. S., Hoodless, P., Weinstein, D. C., Bachvarova, R. F. and Darnell, J. E. J. (1994). Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc. Natl. Acad. Sci. USA 91, 7598-7602.
12. Duncan, S. A., Nagy, A. and Chan, W. (1997). Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos. Development 124, 279-287.
13. Duncan, S. A., Navas, M. A., Dufort, D., Rossant, J. and Stoffel, M. (1998). Regulation of a transcription factor network required for differentiation and metabolism. Science 281, 692-695.
14. George, E. L., Georges-Labouesse, E. N., Patel-King, R. S., Rayburn, H. and Hynes, R. O. (1993). Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 119, 1079-1091.
15. Gu, H., Zhou, Y. R. and Rajewsky, K. (1993). Independent control of immunoglobulin switch at individual switch regions evidenced through the Cre-loxP-mediated gene targeting. Cell 73, 1155-1164.
16. Guillemot, F., Nagy, A., Auerbach, A., Rossant, J. and Joyner, A. L. (1994). Essential role of Mash-2 in extraembryonic development. Nature 371, 333-336.
17. Horikawa, Y., Iwasaki, N., Hara, M., Furuta, H., Hinokio, Y., Cockburn, B. N., Lindner, T., Yamagata, K., Ogata, M., Tomonaga, O. et al. (1997) Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nature Genet. 17, 384-385.
18. Keller, G. M. (1995). In vitro differentiation of embryonic stem cells. Curr. Opin. Cell Biol 7, 862-869.
19. Koopman, P. (1993). Analysis of gene expression by reverse transcriptase-polymerase chain reaction. In Essential Developmental Biology; a Practical Approach, (ed. C. D. Stern and P. W. H. Holland), pp. 231-242. Oxford: IRL Press Limited.
20. d conditional lethal mutation. Mammalian Genome 9, 998-1001.
21. McClatchey, A. I., Saotome, I., Ramesh, V., Gusella, J. F. and Jacks, T. (1997). The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes Dev. 11, 1253-1265.
22. Meehan, R. R., Barlow, D. P., Hill, R. E., Hogan, B. L. M. and Hastie, N. D. (1984). Pattern of serum protein gene expression in mouse visceral yolk sac and foetal liver. EMBO J. 3, 1881-1885.
23. Monaghan, A. P., Kaestner, K. H., Grau, E. and Schutz, G. (1993) Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development 119, 567-578.
24. Morrisey, E. E., Tang, Z., Sigrist, K., Lu, M. M., Jiang, F., Ip, H. S. and Parmacek, M. S. (1998). GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev. 12, 3579-3590.
25. Mortensen, R. M., Conner, D. A., Chao, S., Geisterfer-Lowrance, A. A. and Seidman, J. G. (1992). Production of homozygous mutant ES cells with a single targeting construct. Mol. Cell. Biol. 12, 2391-2395.
26. Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W. and Roder, J. C. (1993). Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428.
27. Nishigori, H., Yamada, S., Kohama, T., Tomura, H., Sho, K., Horikawa, Y., Bell, G. I., Takeuchi, T. and Takeda, J. (1998). Frameshift mutation, A263fsinsGG, in the hepatocyte nuclear factor-1beta gene associated with diabetes and renal dysfunction. Diabetes 47, 1354-1355.
28. Ott, M. O., Rey-Campos, J., Cereghini, S. and Yaniv, M. (1991). vHNF1 is expressed in epithelial cells of distinct embryonic origin during development and precedes HNF1 expression. Mech. Dev. 36, 47-58.
29. Pontoglio, M., Barra, J., Hadchouel, M., Doyen, A., Kress, C., Bach, J. P., Babinet, C. and Yaniv, M. (1996). Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome. Cell 84, 575-585.
30. Pontoglio, M., Sreenan, S., Roe, M., Pugh, W., Ostrega, D., Doyen, A., Pick, A. J., Baldwin, A., Velho, G., Froguel, P. et al. (1998). Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. J. Clin. Invest. 101, 2215-2222.
31. Radice, G. L., Rayburn, H., Matsunami, H., Knudsen, K. A., Takeichi, M. and Hynes, R. O. (1997). Developmental defects in mouse embryos lacking N-cadherin. Dev. Biol. 181, 64-78.
32. Roberts, D. J., Smith, D. M., Goff, D. J. and Tabin, C. J. (1998). Epithelial-mesenchymal signaling during the regionalization of the chick gut. Development 125, 2791-2801.
33. Rossant, J. and Spence, A. (1998). Chimeras and mosaics in mouse mutant analysis. Trends Genet. 14, 358-363.
34. Rudnicki, M. A. and McBurney, M. W. (1987). Cell culture methods and induction of differentiation of embryonal carcinoma cell lines. In Teratocarcinomas and Embryonic Stem cells: a Practical Approach, (ed. E. J. Robertson), pp. 19-49. Oxford: IRL Press Limited.
35. Sirard, C., de la Pompa, J. L., Elia, A., Itie, A., Mirtsos, C., Cheung, A., Hahn, S., Wakeham, A., Schwartz, L., Kern, S. E. et al. (1998). The tumor suppressor gene Smad4/Dpc4 is required for gastrulalion and later for anterior development of the mouse embryo. Genes Dev. 12, 107-119.
36. Soudais, C., Bielinska, M., Heikinheimo, M., MacArthur, C. A., Narita, N., Saffitz, J. E., Simon, M. C., Leiden, J. M. and Wilson, D. B. (1995). Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro. Development 121, 3877-3888.
37. Spyropoulos, D. D. and Capecchi, M. R. (1994). Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. Genes Dev. 8, 1949-1961.
38. Taraviras, S., Monaghan, A. P., Schutz, G. and Kelsey, G. (1994). Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis. Mech. Dev. 48, 67-79.
39. Thisse, C. and Thisse, B. (1998). Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction. Development 126, 229-240.
40. Tronche, F. and Yaniv, M. (1992). HNF1, a homeodomain member of the hepatic transcription regulatory network. BioEssays 14, 579-587.
41. Tronche, F., Bach, I., Chouard, T., David-Wattine, B., Pontoglio, M., Ringeisen, F., Sourdive, D., Thépot, D. and Yaniv, M. (1994). Hepatocyte Nuclear factor 1 (HNF1) and liver gene expression. In Liver Gene Expression, (ed. F. Tronche and M. Yaniv), pp. 155-181. Austin: R. G. Landes Company.
42. Tybulewicz, V. L., Crawford, C. E., Jackson, P. K., Bronson, R. T. and Mulligan, R. C. (1991). Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65, 1153-1163.
43. Weinstein, D. C., Ruiz i Altaba, A., Chen, W. S., Hoodless, P., Prezioso, V. R., Jessell, T. M. and Darnell, J. E. J. (1994). The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell 78, 575-588.
44. Wiles, M. V. (1993). Embryonic stem cells differentiation in vitro. In Methods in Enzymology, vol. 225, pp 900-918. New York: Academic Press Inc.
45. Xanthopoulos, K. G., Prezioso, V. R., Chen, W. S., Sladek, F. M., Cortese, R. and Darnell, J. E. J. (1991). The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription. Proc. Natl. Acad. Sci. USA 88, 3807-3811.
46. Yamaguchi, T. P., Harpal, K., Henkemeyer, M. and Rossant, J. (1994). fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev. 8, 3032-3044.
47. Yamamoto, H., Flannery, M. L., Kupriyanov, S., Pearce, J., McKercher, S. R., Henkel, G. W., Maki, R. A., Werb, Z. and Oshima, R. G. (1998). Defective trophoblast function in mice with a targeted mutation of Ets2. Genes Dev. 12, 1315-1326.
48. Yang, J. T., Rayburn, H. and Hynes, R. O. (1993). Embryonic mesodermal defects in α5 integrin-deficient mice. Development 119, 1093-1105.