Dual role of NF-κB in apoptosis of THP-1 cells during treatment with etoposide and lipopolysaccharide

Leukemia Research

Volumn 28, Issue 1, 2004, Pages 63-69

  Sato, Keiko ^a   Taniguchi, Takahiro ^a   Suzuki, Maiko ^a   Shinohara, Fumiaki ^a   Takada, Haruhiko ^a   Rikiishi, Hidemi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bax; Etoposide; Lipopolysaccharide; NF B; THP 1 cells; XIAP

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3 INHIBITOR; CYCLOHEXIMIDE; DACTINOMYCIN; ETOPOSIDE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TOSYLLYSYL CHLOROMETHYL KETONE;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOLECULAR BIOLOGY; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROTEIN FUNCTION; X CHROMOSOME LINKAGE;

EID: 0242468282     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(03)00127-9     Document Type: Article

References (25)

1. Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1995;1456-1462.
2. Fisher D.E. Apoptosis in cancer therapy: crossing the threshold. Cell. 78:1994;539-542.
3. Kingma P.S., Osheroff N. The response of eukaryotic topoisomerases to DNA damage. Biochim. Biophys. Acta. 1400:1998;223-232.
4. Evan G., Littlewood T. A matter of life and cell death. Science. 281:1998;1317-1322.
5. Jia L., Patwari Y., Srinivasula S.M., Newland A.C., Fernandes-Alnemri T., Alnemri E.S., et al. Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis. Oncogene. 20:2001;4817-4826.
6. Kasibhatla S., Brunner T., Genestier L., Echeverri F., Mahboubi A., Green D.R. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1. Mol. Cell. 1:1998;543-551.
7. Beg A.A., Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science. 274:1996;782-787.
8. Wang C.Y., Guttridge D.C., Mayo M.W., Baldwin A.S. Jr. NF-κB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol. Cell. Biol. 19:1999;5923-5929.
9. Wang C.Y., Mayo M.W., Korneluk R.G., Goeddel D.V., Baldwin A.S. Jr. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 281:1998;1680-1683.
10. Stehlik C., de Martin R., Kumabashiri I., Schmid J.A., Binder B.R., Lipp J. Nuclear factor (NF)-kappa B-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis. J. Exp. Med. 188:1998;211-216.
11. Tang G., Yang J., Minemoto Y., Lin A. Blocking caspase-3-mediated proteolysis of IKKβ suppresses TNF-α-induced apoptosis. Mol. Cell. 8:2001;1005-1016.
12. Manna S.K., Aggarwal B.B. Lipopolysaccharide inhibits TNF-induced apoptosis: role of nuclear factor-κB activation and reactive oxygen intermediates. J. Immunol. 162:1999;1510-1518.
13. Thompson J.E., Phillips R.J., Erdjument-Bromage H., Tempst P., Ghosh S. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell. 80:1995;573-582.
14. Pahl H.L. Activators and target genes of Rel/NF-κB transcription factors. Oncogene. 18:1999;6853-6866.
15. Jeong J.Y., Kim K.U., Jue D.M. Tosylphenylalanine chloromethyl ketone inhibits TNF-α mRNA synthesis in the presence of activated NF-κB in RAW 264.7 macrophages. Immunology. 92:1997;267-273.
16. Tabata M., Tabata R., Grabowski D.R., Bukowski R.M., Ganapathi M.K., Ganapathi R. Role of NF-κB and 26S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma. J. Biol. Chem. 276:2001;8029-8036.
17. Henkel T., Machleidt T., Alkalay I., Ben-Neriah Y., Kronke M., Baeuerle P.A. Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB. Nature. 365:1993;82-85.
18. Bentires-Alj M., Dejardin E., Viatour P., van Lint C., Froesch B., Reed J.C., et al. Inhibition of the NF-κB transcription factor increases Bax expression in cancer cell lines. Oncogene. 20:2001;2805-2813.
19. Li P., Nijhawan D., Budihardjo I., Srinivasula S., Ahmad M., Alnemri E., et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
20. Lassus P., Opitz-Araya X., Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science. 297:2002;1352-1354.
21. Le Bail O., Schmidt-Ullrich R., Israel A. Promoter analysis of the gene encoding the IκBα/MAD3 inhibitor of NF-κB: positive regulation by members of the rel/NF-κB family. EMBO J. 12:1993;5043-5049.
22. Widmann C., Gerwins P., Johnson N.L., Jarpe M.B., Johnson G.L. MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis. Mol. Cell. Biol. 18:1998;2416-2429.
23. Lin H., Chen C., Li X., Chen B.D. Activation of the MEK/MAPK pathway is involved in bryostatin 1-induced monocytic differentiation and up-regulation of X-linked inhibitor of apoptosis protein. Exp. Cell. Res. 272:2002;192-198.
24. Nechushtan A., Smith C.L., Hsu Y.T., Youle R.J. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J. 18:1999;2330-2341.
25. Deveraux Q.L., Roy N., Stennicke H.R., Arsdale T.V., Zhou Q., Srinivasula S.M., et al. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 17:1998;2215-2223.