Roles of NF-κB and 26 S Proteasome in Apoptotic Cell Death Induced by Topoisomerase I and II Poisons in Human Nonsmall Cell Lung Carcinoma

Journal of Biological Chemistry

Volumn 276, Issue 11, 2001, Pages 8029-8036

  Tabata, Masahiro ^b   Tabata, Rika ^b   Grabowski, Dale R ^b   Bukowski, Ronald M ^b   Ganapathi, Mahrukh K ^b   Ganapathi, Ram ^a  

^a TAUSSIG CANCER INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; DNA; DRUG THERAPY; MUTAGENESIS; TOXIC MATERIALS;

BINDING ACTIVITIES; MITOCHONDRIAL RELEASE; TRANSCRIPTION;

CELL CULTURE;

7 ETHYL 10 HYDROXYCAMPTOTHECIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEASOME; 7-ETHYL-10-HYDROXYCAMPTOTHECIN; ATP DEPENDENT 26S PROTEASE; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CAMPTOTHECIN; CISPLATIN; DNA; DNA BINDING PROTEIN; DRUG DERIVATIVE; ENZYME INHIBITOR; I KAPPA B; LEUPEPTIN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PACLITAXEL; PEPTIDE HYDROLASE;

APOPTOSIS; ARTICLE; CELL DEATH; DNA DAMAGE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; DRUG ANTAGONISM; DRUG EFFECT; LUNG TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY;

APOPTOSIS; CAMPTOTHECIN; CARCINOMA, NON-SMALL-CELL LUNG; CISPLATIN; DNA; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; ENZYME INHIBITORS; ETOPOSIDE; HUMANS; I-KAPPA B PROTEINS; LEUPEPTINS; LUNG NEOPLASMS; NF-KAPPA B; PACLITAXEL; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 0035896601     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009831200     Document Type: Article

References (23)

1. Hoffman, P. C., Mauer, A. M., and Vokes, E. E. (2000) Lancet 355, 479-485
2. Schneider, E., Hsiang, Y-W., and Liu, L. F. (1990) Adv. Pharmacol. 21, 149-183
3. Chen, A. Y., and Liu, L. F. (1994) Annu. Rev. Pharmacol. Toxicol. 36, 191-218
4. Pommier, Y., Leteurtre, F., Fesen, M. R., Fujimori, A., Bertrand, R., Solary, E., Kohlhagen, G., and Kohn, K. W. (1994) Cancer Invest. 12, 530-542
5. Chen, K-V., Pasta, I., and Gottesman, M. M. (1993) Adv. Cancer Res. 60, 157-180
6. Ganapathi, R., Kuo, T., Teeter, L., Grabowski, D., and Ford, J. (1991) Mol. Pharmacol. 39, 1-8
7. Lenardo, M. J., and Baltimore, D. (1989) Cell 58, 227-229.
8. Barnes, P. J., and Karin, M. (1997) N. Engl. J. Med. 336, 1066-1071
9. Rayet, B., and Gelinas, C. (1999) Oncogene 18, 6938-6947
10. Beg, A. A., and Baltimore, D. (1996) Science 274, 782-784
11. Cusack, J. C., Liu, R., and Baldwin, A. S. (1999) Drug Resistance Updates 2, 271-273
12. Schmitt, S. E., Sane, A-T., and Bertrand, R. (1999) Drug Resistance Updates 2, 21-29
13. Bentires-Alj, M., Hellin, A-C., Ameyar, M., Chouaib, S., Merville, M-P., and Bours, V. (1999) Cancer Res. 59, 811-815
14. Pajonk, F., Pajonk, K., and McBride, W. H. (1999) J. Natl. Cancer Inst. 91, 1956-1960
15. Ganapathi, M. K., Weizer, A. K., Borsellino, S., Bukowski, R. M., Ganapathi, R., Rice, T., Casey, G., and Kawamura, K-I. (1996) Cell Growth Differ. 7, 923-929
16. Grabowski, D., Holmes, K. A., Aoyama, M., Ye, Y., Rybicki, L. A., Bukowski, R. M., Ganapathi, M. K., Hickson, I. D., and Ganapathi, R. (1999) Mol. Pharmacol. 56, 1340-1345
17. Muscarella, D. E., Rachlinski, M. K., Sotiriadis, J., and Bloom, S. E. (1998) Exp. Cell Res. 238, 155-167
18. Kawamura, K-I., Grabowski, D., Krivacic, K., Hidaka, H., and Ganapathi, R. (1996) Biochem. Pharmacol. 52, 1903-1909
19. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
20. Boland, M. P., Foster, S. J., and O'Neill, L. A. J. (1997) J. Biol. Chem. 272, 12952-12960
21. Sun, X-M., MacFarlane, M., Zhuang, J., Wolf, B. B., Green, D. R., and Cohen, G. M. (1999) J. Biol. Chem. 274, 50553-5060
22. Palombella, V. J., Rando, O. J., Goldberg, A. L., and Maniatis, T. (1994) Cell 78, 773-785
23. Desai, S. D., Liu, L. F., Vazquez-Abad, D., and D'Arpa, P. (1997) J. Biol. Chem. 272, 24159-24164