A Neisserial autotransporter NaIP modulating the processing of other autotransporters

Molecular Microbiology

Volumn 50, Issue 3, 2003, Pages 1017-1030

  Van Ulsen, Peter ^a,b,c   Van Alphen, Loek ^c   Ten Hove, Jan ^d   Fransen, Floris ^a   Van Der Ley, Peter ^c   Tommassen, Jan ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c NETHERLANDS VACCINE INSTITUTE   (Netherlands)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; AUTOTRANSPORTER; CARRIER PROTEIN; IGA PROTEINASE; LIPOPROTEIN; PROTEIN APP; PROTEIN NALP; SERINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL OUTER MEMBRANE; BACTERIAL VIRULENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; GRAM NEGATIVE BACTERIUM; HAEMOPHILUS INFLUENZAE; MASS SPECTROMETRY; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN TRANSPORT;

BACTERIA (MICROORGANISMS); HAEMOPHILUS; HAEMOPHILUS INFLUENZAE; NEGIBACTERIA; NEISSERIA; NEISSERIA MENINGITIDIS;

EID: 0242437804     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03773.x     Document Type: Article

References (50)

1. Abdel-Hadi, H.A., Wooldridge, K.G., Robinson, K., and Ala'Aldeen, D.A. (2001) Identification and characterization of App: an immunogenic autotransporter protein of Neisseria meningitidis. Mol Microbiol 41: 611-623.
2. Ait-Tahar, K., Wooldridge, K.G., Turner, D.P., Atta, M., Todd, I., and Ala'Aldeen, D.A. (2000) Auto-transporter A protein of Neisseria meningitidis: a potent CD4+ T-cell and B-cell stimulating antigen detected by expression cloning. Mol Microbiol 37: 1094-1105.
3. Benz, I., and Schmidt, M.A. (1992) AIDA-I, the adhesin involved in diffuse adherence of the diarrhoeagenic Escherichia coli strain 2787 (O126: H27), is synthesized via a precursor molecule. Mol Microbiol 6: 1539-1546.
4. Brooks, G.F., Lammel, C.J., Blake, M.S., Kusecek, B., and Achtman, M. (1992) Antibodies against IgA1 protease are stimulated both by clinical disease and asymptomatic carriage of serogroup A Neisseria meningitidis. J Infect Dis 166: 1316-1321.
5. Caugant, D.A., Kristiansen, B.E., Froholm, L.O., Bovre, K., and Selander, R.K. (1988) Clonal diversity of Neisseria meningitidis from a population of asymptomatic carriers. Infect Immun 56: 2060-2068.
6. Coutte, L., Antoine, R., Drobecq, H., Locht, C., and Jacob-Dubuisson, F. (2001) Subtilisin-like autotransporter serves as maturation protease in a bacterial secretion pathway. EMBO J 20: 5040-5048.
7. Coutte, L., Willery, E., Antoine, R., Drobecq, H., Locht, C., and Jacob-Dubuisson, F. (2003a) Surface anchoring of bacterial subtilisin important for maturation function. Mol Microbiol 49: 529-539.
8. Coutte, L., Alonso, S., Reveneau, N., Willery, E., Quatannens, B., Locht, C., and Jacob-Dubuisson, F. (2003b) Role of adhesin release for mucosal colonization by a bacterial pathogen. J Exp Med 197: 735-742.
9. Fernandez, R.C., and Weiss, A.A. (1994) Cloning and sequencing of a Bordetella pertussis serum resistance locus. Infect Immun 62: 4727-4738.
10. Fink, D.L., and St Geme, J.W. III (2003) Chromosomal expression of the Haemophilus influenzae Hap autotransporter allows fine-tuned regulation of adhesive potential via inhibition of intermolecular autoproteolysis. J Bacteriol 185: 1608-1615.
11. Fink, D.L., Cope, L.D., Hansen, E.J., and St. Geme, J.W. III (2001) The Hemophilus influenzae Hap autotransporter is a chymotrypsin clan serine protease and undergoes autoproteolysis via an intermolecular mechanism. J Biol Chem 276: 39492-39500.
12. Halter, R., Pohlner, J., and Meyer, T.F. (1989) Mosaic-like organization of IgA protease genes in Neisseria gonorrhoeae generated by horizontal genetic exchange in vivo. EMBO J 8: 2737-2744.
13. Henderson, I.R., and Nataro, J.P. (2001) Virulence functions of autotransporter proteins. Infect Immun 69: 1231-1243.
14. Henderson, I.R., Navarro-Garcia, F., and Nataro, J.P. (1998) The great escape: structure and function of the autotransporter proteins. Trends Microbiol 6: 370-378.
15. Hendrixson, D.R., de la Morena, M.L., Stathopoulos, C., and St. Geme, J.W. (1997) Structural determinants of processing and secretion of the Haemophilus influenzae Hap protein. Mol Microbiol 26: 505-518.
16. Huang, J.Z., and Schell, M.A. (1990) Evidence that extracellular export of the endoglucanase encoded by egl of Pseudomonas solanacearum occurs by a two-step process involving a lipoprotein intermediate. J Biol Chem 265: 11628-11632.
17. Inukai, M., Takeuchi, K., Shimizu, K., and Arai, M. (1978) Mechanism of action of globomycin. J Antibiot 31: 1203-1205.
18. Jose, J., Wölk, U., Lorenzen, D., Wenschuh, H., and Meyer, T.F. (2000) Human T-cell response to meningococcal immunoglobulin A1 protease associated alpha-proteins. Scand J Immunol 51: 176-185.
19. Klauser, T., Pohlner, J., and Meyer, T.F. (1990) Extracellular transport of cholera toxin B subunit using Neisseria IgA protease beta-domain: conformation-dependent outer membrane translocation. EMBO J 9: 1991-1999.
20. Koster, M., Bitter, W., and Tommassen, J. (2000) Protein secretion mechanisms in Gram-negative bacteria. Int J Med Microbiol 290: 325-331.
21. van der Ley, P., and Poolman, J.T. (1992) Construction of a multivalent meningococcal vaccine strain based on the class 1 outer membrane protein. Infect Immun 60: 3156-3161.
22. Lomholt, H., Poulsen, K., and Kilian, M. (1995) Comparative characterization of the iga gene encoding IgA1 protease in Neisseria meningitidis, Neisseria gonorrhoeae and Haemophilus influenzae. Mol Microbiol 15: 495-506.
23. Maurer, J., Jose, J., and Meyer, T.F. (1997) Autodisplay: one-component system for efficient surface display and release of soluble recombinant proteins from Escherichia coli. J Bacteriol 179: 794-804.
24. Maurer, J., Jose, J., and Meyer, T.F. (1999) Characterization of the essential transport function of the AIDA-I autotransporter and evidence supporting structural predictions. J Bacteriol 181: 7014-7020.
25. (n): technical design and applications to peptide and protein analysis. J Sep Sci 25: 557-568.
26. Odenbreit, S., Till, M., Hofreuter, D., Faller, G., and Raas, R. (1999) Genetic and functional characterization of the alpAB gene locus essential for the adhesion of Helicobacter pylori to human gastric tissue. Mol Microbiol 31: 1537-1548.
27. Pagotto, F.J., Salimnia, H., Totten, P.A., and Dillon, J.R. (2000) Stable shuttle vectors for Neisseria gonorrhoeae, Haemophilus spp. & other bacteria based on a single origin of replication. Gene 244: 13-19.
28. Parkhill, J., Achtman, M., James, K.D., Bentley, S.D., Churcher, C., Klee, S.R., et al. (2000) Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. Nature 404: 502-506.
29. Peltola, H. (1983) Meningococcal disease: still with us. Rev Infect Dis 5: 71-91.
30. Pohlner, J., Halter, R., Beyreuther, K., and Meyer, T.F. (1987) Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease. Nature 325: 458-462.
31. Pohlner, J., Langenberg, U., Wolk, U., Beck, S.C., and Meyer, T.F. (1995) Uptake and nuclear transport of Neisseria IgA1 protease-associated alpha-proteins in human cells. Mol Microbiol 17: 1073-1083.
32. Pugsley, A.P., and Kornacker, M.G. (1991) Secretion of the cell surface lipoprotein pullulanase in Escherichia coli. Cooperation or competition between the specific secretion pathway and the lipoprotein-sorting pathway. J Biol Chem 266: 13640-13645.
33. St. Geme, J.W., de la Morena, M.L., and Falkow, S. (1994) A Haemophilus influenzae IgA protease-like protein promotes intimate interaction with human epithelial cells. Mol Microbiol 14: 217-233.
34. Sankaran, K., and Wu, H.C. (1994) Lipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol. J Biol Chem 269: 19701-19706.
35. Saunders, N.J., Jeffries, A.C., Peden, J.F., Hood, D.W., Tettelin, H., Rappuoli, R., and Moxon, E.R. (2000) Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58. Mol Microbiol 37: 207-215.
36. Schmitt, W., and Haas, R. (1994) Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein. Mol Microbiol 12: 307-319.
37. Serruto, D., Adu-Bobie, J., Scarselli, M., Veggi, D., Pizza, M., Rappuoli, R., and Aricò, B. (2003) Neisseria meningitidis App, a new adhesin with autocatalytic serine protease activity. Mol Microbiol 48: 323-334.
38. Suzuki, T., Lett, M.C., and Sasakawa, C. (1995) Extracellular transport of VirG protein in Shigella. J Biol Chem 270: 30874-30880.
39. Tettelin, H., Saunders, N.J., Heidelberg, J., Jeffries, A.C., Nelson, K.E., Eisen, J.A., et al. (2000) Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science 287: 1809-1815.
40. Thanassi, D.G., and Hultgren, S.J. (2000) Multiple pathways allow protein secretion across the bacterial outer membrane. Curr Opin Cell Biol 12: 420-430.
41. Turner, D.P., Wooldridge, K.G., and Ala'Aldeen, D.A. (2002) Autotransported serine protease A of Neisseria meningitidis: an immunogenic, surface-exposed outer membrane, and secreted protein. Infect Immun 70: 4447-4461.
42. Tzeng, Y.L., and Stephens, D.S. (2000) Epidemiology and pathogenesis of Neisseria meningitidis. Microbes Infect 2: 687-700.
43. van Ulsen, P., Van Alphen, L., Hopman, C.T., Van der Ende, A., and Tommassen, J. (2001) In vivo expression of Neisseria meningitidis proteins homologous to the Haemophilus influenzae Hap and Hia autotransporters. FEMS Immunol Med Microbiol 32: 53-64.
44. Valls, M., Atrian, S., De Lorenzo, V., and Fernandez, L.A. (2000) Engineering a mouse metallothionein on the cell surface of Ralstonia eutropha CH34 for immobilization of heavy metals in soil. Nat Biotechnol 18: 661-665.
45. Veiga, E., Sugawara, E., Nikaido, H., De Lorenzo, V., and Fernandez, L.A. (2002) Export of autotransported proteins proceeds through an oligomeric ring shaped by C-terminal domains. EMBO J 21: 2122-2131.
46. Vieira, J., and Messing, J. (1982) The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene 19: 189-194.
47. Voulhoux, R., Bos, M.P., Geurtsen, J., Mols, M., and Tommassen, J. (2003) Role of ahighly conserved bacterial protein in outer membrane protein assembly. Science 299: 262-265.
48. Wilhelm, S., Tommassen, J., and Jaeger, K.E. (1999) A novel lipolytic enzyme located in the outer membrane of Pseudomonas aeruginosa. J Bacteriol 181: 6977-6986.
49. Willems, R.J., Geuijen, C., Van der Heide, H.G., Renauld, G., Bertin, P., Van den Akker, W.M., et al. (1994) Mutational analysis of the Bordetella pertussis fim/fha gene cluster: identification of a gene with sequence similarities to haemolysin accessory genes involved in export of FHA. Mol Microbiol 11: 337-347.
50. Yanagida, N., Uozumi, T., and Beppu, T. (1986) Specific excretion of Serratia marcescens protease through the outer membrane of Escherichia coli. J Bacteriol 166: 937-944.