In vivo expression of Neisseria meningitidis proteins homologous to the Haemophilus influenzae Hap and Hia autotransporters

FEMS Immunology and Medical Microbiology

Volumn 32, Issue 1, 2001, Pages 53-64

  Van Ulsen, Peter ^a,b   Van Alphen, Loek ^b   Hopman, Carla Th P ^c   Van der Ende, Arie ^c   Tommassen, Jan ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Adhesin; Autotransporter; In vivo expression; Neisseria meningitidis; Outer membrane protein

Indexed keywords

BACTERIAL PROTEIN; IMMUNOGLOBULIN A1 PROTEASE; PROTEIN ANTIBODY; PROTEIN HAP; PROTEIN HIA; PROTEINASE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL MENINGITIS; CARBOXY TERMINAL SEQUENCE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; GENE SEQUENCE; HAEMOPHILUS INFLUENZAE; HUMAN; IMMUNOGENICITY; MALE; MOLECULAR CLONING; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

ADHESINS, BACTERIAL; ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; CHILD; CHILD, PRESCHOOL; CLONING, MOLECULAR; ESCHERICHIA COLI; FEMALE; HAEMOPHILUS INFLUENZAE; HUMANS; MALE; MENINGOCOCCAL INFECTIONS; MENINGOCOCCAL VACCINES; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEISSERIA MENINGITIDIS; OPEN READING FRAMES; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES;

EID: 0035663001     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(01)00271-1     Document Type: Article

References (34)

1. Meningococcal disease: Still with us
2. Epidemiology and pathogenesis of Neisseria meningitidis
3. Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway
4. Immunogenicity and safety of a hexavalent meningococcal outer-membrane-vesicle vaccine in children of 2-3 and 7-8 years of age
5. Effect of sequence variation in meningococcal PorA outer membrane protein on the effectiveness of a hexavalent PorA outer membrane vesicle vaccine
6. Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491
7. Complete genome sequence of Neisseria meningitidis serogroup B strain MC58
8. A novel family of channel-forming, autotransporting, bacterial virulence factors
9. The great escape: Structure and function of the autotransporter proteins
10. Antibody and cell-mediated immune responses to booster immunization with a new acellular pertussis vaccine in school children
11. Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease
12. Comparative characterization of the iga gene encoding IgA1 protease in Neisseria meningitidis, Neisseria gonorrhoeae and Haemophilus influenzae
13. Tetranucleotide repeats identify novel virulence determinant homologues in Neisseria meningitidis
14. Identification and characterisation of a novel conserved outer membrane protein from Neisseria meningitidis
15. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
16. Clonal diversity of Neisseria meningitidis from a population of asymptomatic carriers
17. Identification of a glycoprotein produced by enterotoxigenic Escherichia coli
18. Characterization of an exported protease from Shiga toxin-producing Escherichia coli
19. Vag8, a Bordetella pertussis bvg-regulated protein
20. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
21. A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
22. Structural determinants of processing and secretion of the Haemophilus influenzae Hap protein
23. Use of T7 RNA polymerase to direct expression of cloned genes
24. Molecular characterization of the structural gene for the lactoferrin receptor of the meningococcal strain H44/76
25. Mutational analysis of the Bordetella pertussis fim/fha gene cluster: Identification of a gene with sequence similarities to haemolysin accessory genes involved in export of FHA
26. Identification of a second family of high-molecular-weight adhesion proteins expressed by non-typable Haemophilus influenzae
27. The Haemophilus influenzae Hap serine protease promotes adherence and microcolony formation, potentiated by a soluble host protein
28. Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58
29. The Haemophilus influenzae Hia adhesin is an autotransporter protein that remains uncleaved at the C terminus and fully cell associated
30. Virulence functions of autotransporter proteins
31. Auto-transporter A protein of Neisseria meningitidis: A potent CD4+ T-cell and B-cell stimulating antigen detected by expression cloning
32. A Haemophilus influenzae IgA protease-like protein promotes intimate interaction with human epithelial cells
33. Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
34. Recognition of a bacterial adhesion by an integrin: Macrophage CR3 (αMβ2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis