Paraoxonase-2 G148 variant in an aboriginal Canadian girl with non-insulin-dependent diabetes [7]

Lancet

Volumn 350, Issue 9080, 1997, Pages 785-

  Hegele, Robert A ^a   Connelly, Philip W ^b   Scherer, Stephen W ^b   Hanley, Anthony J G ^b   Harris, Stewart B ^b   Tsui, Lap Chee ^b   Zinman, Bernard ^b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARYLESTERASE; ENZYME VARIANT; GENE PRODUCT; GLUCOSE;

ABORIGINE; ADIPOSE TISSUE; BODY FAT; CANADA; CASE REPORT; CHROMOSOME 7Q; DISEASE SEVERITY; ETIOLOGY; FEMALE; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOME; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HOMOZYGOSITY; HUMAN; LETTER; MULTIGENE FAMILY; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; PANCREAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD;

EID: 0343923422     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)62570-6     Document Type: Article

References (5)

1. Prochazka M, Thompson B, Scherer SW, et al. Linkage and association of insulin resistance and NIDDM with markers at 7q21.3-q22.1 in the Pima Indians. Diabetes 1996; 45: 42A.
2. Humbert R, Adler DA, Disteche CM, Hassett C, Omiecinski CJ, Furlong CE. The molecular basis of the human serum plasma paraoxonase activity polymorphism. Nat Genet 1993; 3: 73-76.
3. Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN. The human serum paraoxonase/arylestcrase gene (PON1) is one member of a multigene family. Genomics 1996; 33: 498-507.
4. Harris SB, Gittelsohn J, Hanley AGJ, et al. The prevalence of NIDDM and associated risk factors in native Canadians. Diabetes Care 1997; 20: 185-97.
5. Hegele RA, Connelly PW, Scherer SW, et al. Paraoxonase-2-gene (PON2) G148 variant associated with elevated fasting plasma glucose in NIDDM. J Clin Endocrinol Metab (in press).