Sex differences in response to oral amitriptyline in three animal models of depression in C57BL/6J mice

Psychopharmacology

Volumn 170, Issue 1, 2003, Pages 94-101

  Caldarone, B J ^a   Karthigeyan, K ^a   Harrist, A ^a   Hunsberger, J G ^a   Wittmack, E ^a   King, S L ^a   Jatlow, P ^a   Picciotto, M R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antidepressant; Forced swim; Gender; Learned helplessness; Tail suspension

Indexed keywords

AMITRIPTYLINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; FEMALE; FORCED SWIMMING TEST; LEARNED HELPLESSNESS; LOCOMOTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; SEX DIFFERENCE;

ADMINISTRATION, ORAL; AMITRIPTYLINE; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; FEMALE; HELPLESSNESS, LEARNED; HINDLIMB SUSPENSION; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; SEX FACTORS; SWIMMING;

EID: 0242407444     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1518-7     Document Type: Article

References (51)

1. Anisman H, Hayley S, Kelly O, Borowski T, Merali Z (2001) Psychogenic, neurogenic, and systemic stressor effects on plasma corticosterone and behavior: mouse strain-dependent outcomes. Behav Neurosci 115:443-454
2. Bai F, Li X, Clay M, Lindstrom T, Skolnick P (2001) Intra-and interstrain differences in models of "behavioral despair". Pharmacol Biochem Behav 70:187-192
3. 2 receptors. Nature 377:424-428
4. Blier P, de Montigny C (1994) Current advances and trends in the treatment of depression. Trends Pharmacol Sci 15:220-226
5. Bourtchuladze R, Frenguelli B, Blendy J, Cioffi D, Schutz G, Silva AJ (1994) Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell 79:59-68
6. Breyer-Pfaff U, Gaertner HJ, Giedke H (1982) Plasma levels, psychophysiological variables, and clinical response to amitriptyline. Psychiatry Res 6:223-34
7. Breyer-Pfaff U, Giedke H, Gaertner HJ, Nill K (1989) Validation of a therapeutic plasma level range in amitriptyline treatment of depression. J Clin Psychopharmacol 9:116-121
8. Caldarone BJ, George TP, Zachariou V, Picciotto MR (2000) Gender differences in learned helplessness behavior are influenced by genetic background. Pharmacol Biochem Behav 66:811-817
9. Conti AC, Cryan JF, Dalvi A, Lucki I, Blendy JA (2002) cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs. J Neurosci 22:3262-3268
10. Coudore F, Besson A, Eschalier A, Lavarenne J, Fialip J (1996) Plasma and brain pharmacokinetics of amitriptyline and its demethylated and hydroxylated metabolites after one and six half-life repeated administrations to rats. Gen Pharmacol 27:215-219
11. Cryan JF, Dalvi A, Jin SH, Hirsch BR, Lucki I, Thomas SA (2001) Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. J Pharmacol Exp Ther 298:651-657
12. Cryan JF, Markou A, Lucki I (2002) Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci 23:238-245.
13. Dalvi A, Lucki I (1999) Murine models of depression. Psychopharmacology 147:14-16
14. David DJ, Nic Dhonnchadha BA, Jolliet P, Hascoet M, Bourin M (2001) Are there gender differences in the temperature profile of mice after acute antidepressant administration and exposure to two animal models of depression? Behav Brain Res 119:203-211
15. Ernfors P, Kucera J, Lee KF, Loring J, Jaenisch R (1995) Studies on the physiological role of brain-derived neurotrophic factor and neurotrophin-3 in knockout mice. Int J Dev Biol 39:799-807
16. Holmes A, Yang RJ, Murphy DL, Crawley JN (2002) Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology 27:914-923
17. Izumi J, Washizuka M, Hayashi-Kuwabara Y, Yoshinaga K, Tanaka Y, Ikeda Y, Kiuchi Y, Oguchi K (1997) Evidence for a depressive-like state induced by repeated saline injections in Fischer 344 rats. Pharmacol Biochem Behav 57:883-888
18. Kornstein SG, Schatzberg AF, Thase ME, Yonkers KA, McCullough JP, Keitner GI, Gelenberg AJ, Davis SM, Harrison WM, Keller MB (2000) Gender differences in treatment response to sertraline versus imipramine in chronic depression. Am J Psychiatry 157:1445-1452
19. Leshner AI, Remler H, Biegon A, Samuel D (1979) Desmethylimipramine (DMI) counteracts learned helplessness in rats. Psychopharmacology 66:207-208
20. 2-adrenergic receptor subtypes b and c. Science 273:803-805
21. Liu X, Gershenfeld HK (2001) Genetic differences in the tailsuspension test and its relationship to imipramine response among 11 inbred strains of mice. Biol Psychiatry 49:575-581
22. Lucki I, Dalvi A, Mayorga AJ (2001) Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice. Psychopharmacology 155:315-322
23. 2a-adrenergic receptor subtype. Science 273:801-803
24. Maier SF (1984) Learned helplessness and animal models of depression. Prog Neuropsychopharmacol Biol Psychiatry 8:435-446
25. Maier SF, Seligman ME (1976) Learned helplessness: theory and evidence. J Exp Psychol Gen 105:3-46
26. Mayorga AJ, Dalvi A, Page ME, Zimov-Levinson S, Hen R, Lucki I (2001) Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice. J Pharmacol Exp Ther 298:1101-1107
27. 1A receptor. Proc Natl Acad Sci USA 95:10734-10739
28. Petty F, Sherman AD (1979) Reversal of learned helplessness by imipramine. Commun Psychopharmacol 3:371-373
29. Picciotto MR, Zoli M, Léna C, Bessis A, Lallemand Y, Le Novère N, Vincent P, Merlo-Pich E, Brulet P, Changeux J-P (1995) Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 374:65-67
30. Porsolt RD, Bertin A, Jalfre M (1977) Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther 229:327-336
31. 4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell 90:991-1001
32. Schauwecker PE (2002) Complications associated with genetic background effects in models of experimental epilepsy. Prog Brain Res 135:139-148
33. Schramm NL, McDonald MP, Limbird LE (2001) The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety. J Neurosci 21:4875-4882
34. Shanks N, Anisman H (1988) Stressor-provoked behavioral changes in six strains of mice. Behav Neurosci 102:894-905
35. Shanks N, Anisman H (1989) Strain-specific effects of antidepressants on escape deficits induced by inescapable shock. Psychopharmacology 99:122-128
36. Shapiro BH, Agrawal AK, Pampori NA (1995) Gender differences in drug metabolism regulated by growth hormone. Int J Biochem Cell Biol 27:9-20
37. Sherman AD, Allers GL, Petty F, Henn FA (1979) A neuropharmacologically- relevant animal model of depression. Neuropharmacology 18:891-893
38. Sherman AD, Sacquitne JL, Petty F (1982) Specificity of the learned helplessness model of depression. Pharmacol Biochem Behav 16:449-454
39. Steru L, Chermat R, Thierry B, Simon P (1985) The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 85:367-370
40. Steru L, Chermat R, Thierry B, Mico JA, Lenegre A, Steru M, Simon P, Porsolt RD (1987) The automated tail suspension test: a computerized device which differentiates psychotropic drugs. Prog Neuropsychopharmacol Biol Psychiatry 11:659-671
41. Svenningsson P, Tzavara ET, Witkin JM, Fienberg AA, Nomikos GG, Greengard P (2002) Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac). Proc Natl Acad Sci USA 99:3182-3187
42. Tannenbaum B, Anisman H (2003) Impact of chronic intermittent challenges in stressor-susceptible and resilient strains of mice. Biol Psychiatry 53:292-303
43. 2c serotonin receptors. Nature 374:542-546
44. Telner JI, Singhal RL (1981) Effects of nortriptyline treatment on learned helplessness in the rat. Pharmacol Biochem Behav 14:823-826
45. Ulrich S, Northoff G, Wurthmann C, Partscht G, Pester U, Herscu H, Meyer FP (2001) Serum levels of amitriptyline and therapeutic effect in non-delusional moderately to severely depressed in-patients: a therapeutic window relationship. Pharmacopsychiatry 34:33-40
46. Vaidya VA, Duman RS (2001) Depresssion-emerging insights from neurobiology. Br Med Bull 57:61-79
47. Weissman MM, Klerman GL (1985) Gender and depression. Trends Neurosci 8:416-420
48. Wong ML, Licinio J (2001) Research and treatment approaches to depression. Nat Rev Neurosci 2:343-351
49. 1 receptor mutant mice. Cell 79:945-955
50. Yonkers KA, Brawman-Mintzer O (2002) The pharmacologic treatment of depression: is gender a critical factor? J Clin Psychiatry 63:610-615
51. Ziegler VE, Co BT, Taylor JR, Clayton PJ, Biggs JT (1976) Amitriptyline plasma levels and therapeutic response. Clin Pharmacol Ther 19:795-801