Epilepsy: From consensus to daily practice

Acta Neurologica Scandinavica, Supplement

Volumn 108, Issue 180, 2003, Pages 5-15

  Ben Menachem, E ^a   Scheepers, B ^b   Stodieck, S ^c  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b Lrng and Disabilities Directorate   (United Kingdom)

^c Epilepsiezentrum Hamburg   (Germany)

Author keywords

Evidence based reviews; Monotherapy; Treatment recommendations; Valproate

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETHOSUXIMIDE; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PRIMIDONE; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; BENZODIAZEPINE; ZONISAMIDE;

CLINICAL TRIAL; COGNITIVE DEFECT; CONFERENCE PAPER; CONNECTIVE TISSUE DISEASE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ELECTROENCEPHALOGRAPHY; EPILEPSY; EVIDENCE BASED MEDICINE; FATIGUE; HUMAN; IMPOTENCE; PRACTICE GUIDELINE; TREATMENT OUTCOME; VAGUS NERVE STIMULATION; VISUAL FIELD DEFECT; CLINICAL PRACTICE; CLONIC SEIZURE; DISEASE EXACERBATION; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG RESPONSE; FOCAL EPILEPSY; GRAND MAL EPILEPSY; MEDICAL DECISION MAKING; MONOTHERAPY; MYOCLONUS EPILEPSY; OUTCOMES RESEARCH; SEIZURE; SYNDROME; UNITED KINGDOM; ADULT; DECISION MAKING; DRUG COMBINATION; PATIENT CARE PLANNING; REVIEW;

ADULT; ANTICONVULSANTS; DECISION MAKING; DRUG THERAPY, COMBINATION; EPILEPSY; EVIDENCE-BASED MEDICINE; HUMANS; PATIENT CARE PLANNING; PRACTICE GUIDELINES; VALPROIC ACID;

EID: 0242361677     PISSN: 00651427     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (36)

1. GOWERS WR. Epilepsy and other chronic convulsive diseases. Their causes, symptoms and treatment. New York: William Wood, 1885:255.
2. CHRISTE W, KRAMER G, VIGONIUS U et al. A double-blind controlled clinical trial: oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy. Epilepsy Res 1997;26:451-60.
3. CALLAGHAN N, KENNY RA, O'NEILL B, CROWLEY M, GOGGIN T. A prospective study between carbamazepine, phenytoin and sodium valproate as monotherapy in previously untreated and recently diagnosed patients with epilepsy. J Neurol Neurosurg Psychiatry 1985;45:639-44.
4. RICHENS A, DAVIDSON DL, CARTLIDGE NE, EASTER DJ. A multicentre comparative trial of sodium valproate and carbamazepine in adult onset epilepsy. Adult EPITEG Collaborative Group. J Neurol Neurosurg Psychiatry, 1994;57(6):682-7.
5. MATTSON RH, CRAMER JA, COLLINS JF. A comparison of valproate and carbamazepine for the treatment of complex partial seizures and secondarily generalised tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study, 264. N Engl J Med 1992; 32:765-71.
6. HELLER AJ, CHESTERMAN P, ELWES RD et al. Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial. J Neurol Neurosurg Psychiatry 1995;58:44-50.
7. BRODIE MJ, OVERSTALL PW, GIORGI L. Multicentre, double-blind, randomised comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy. The UK Lamotrigine Elderly Study Group. Epilepsy Res 1999;37:81-7.
8. BRODIE MJ, RICHENS A, YUEN AW. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. UK Lamotrigine/Carbamazepine Monotherapy Trial Group. Lancet 1995;345:476-9.
9. DAM M, EKBERG R, LOYNING Y, WALTIMO O, JAKOBSEN K. A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy. Epilepsy Res 1989;3:70-6.
10. DE SILVA M, MACARDLE B, MCGOWAN M et al. Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy. Lancet 1996;347:709-13.
11. VERITY CM, HOSKING G, EASTER DJ. A multicentre comparative trial of sodium valproate and carbamazepine in paediatric epilepsy. The Paediatric EPITEG Collaborative Group. Dev Med Child Neurol 1995;37:97-108.
12. THILOTHAMMAL N, BANU K, RATNAM RS. Comparison of phenobarbitone, phenytoin with sodium valproate: randomised, double-blind study. Indian Pediatr 1996;33: 549-55.
13. MATTSON RH, CRAMER JA, COLLINS JF et al. Comparison of carbamazepine, phenobarbital, phenytoin and primidone in partial and secondarily generalised tonic-clonic seizures. N Engl J Med 1985;313:145-51.
14. MARSON AG, WILLIAMSON PR, CLOUGH H, HUTTON JL, CHADWICK DW. Carbamazepine versus valproate monotherapy for epilepsy: a meta-analysis. Epilepsia 2002; 43:505-13.
15. CHADWICK DW, ANHUT H, GREINER MJ et al. A double-blind trial of gabapentin monotherapy for newly diagnosed partial seizures. International Gabapentin Monotherapy Study Group 945-77. Neurology 1998;51:1282-8.
16. CHADWICK D. Safety and efficacy of vigabatrin and carbamazepine in newly diagnosed epilepsy: a multicentre randomised double-blind study. Vigabatrin European Monotherapy Study Group. Lancet 1999;354:13-9.
17. KALVIAINEN R, AIKIA M, SAUKKONEN AM, MERVAALA E, RIEKKINEN PJ SR. Vigabatrin vs carbamazepine monotherapy in patients with newly diagnosed epilepsy. A randomised, controlled study. Arch Neurol 1995;52:989-96.
18. BRODIE MJ, CHADWICK DW, ANHUT H et al. Gabapentin versus lamotrigin monotherapy: a double-blind comparison in newly diagnosed epilepsy. Epilepsia 2002;43: 993-1000.
19. PRIVITERA MD, BRODIE MJ, MATTSON RH, CHADWICK DW, NETO W, WANG S. Topiramate, carbamazepine and valproate monotherapy: double-blind comparison in newly diagnosed epilepsy. Acta Neurol Scand 2003;107:165-75.
20. PERUCCA E. Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience. CNS Drugs 2002;16:695-714.
21. LUEF G, CHEMELLI A, BIRBAMER G, AICHNER F, BAUER G. Phenytoin overdosage and cerebellar atrophy in spileptic patients: clinical and MRI findings. Eur Neurol 1994;34:79-81.
22. CALLAGHAN N, O'HARE J, O'DRISCOLL D, O'NEILL B, DALY M. Comparative study of ethosuximide and sodium valproate in the treatment of typical absence seizure (petit mal). Dev Med Child Neurol 1982;24:830-6.
23. SATO S, WHITE BG, PENRY JK et al. Valproic acid versus ethosuximide in the treatment of absence seizures. Neurology 1982;32:157-63.
24. GORDON N. Review: juvenile myoclonic epilepsy. Child Care Health Dev 1994;20:71-6.
25. SUNDQVIST A, THOMSON T, LUNDKVIST B. Valproate as monotherapy for juvenile myoclonic epilepsy: dose-effect study. Ther Drug Monit 1998;20:149-57.
26. GENTON P, GELISSE P, THOMAS P, DRAVET C. Do carbamazepine and phenytoin aggravate juvenile myoclonic epilepsy? Neurology 2000;55:1106-9.
27. MCLEAN MJ. Gabapentin. Epilepsia 1995;36:S73-86.
28. Scottish Intercollegiate Guidelines Network (SIGN). http://www.sign.ac. uk/pdf/qrg21.pdf.
29. The Agency for Healthcare Research and Quality (AHRQ). http://www.ahcpr.gov.
30. MANFORD M, HART YM, SANDER JW, SHORVON SD. The National General Practice Study of Epilepsy. The syndromic classification of the International League Against Epilepsy applied to epilepsy in a general population. Arch Neurol 1992;49:801-8.
31. BERG AT, SHINNAR S, LEVY SR et al. How well can epilepsy syndromes be identified at diagnosis? A reassessment 2 years after initial diagnosis. Epilepsia 2000;41:1269-75.
32. YUEN AW, LAND G, WEATHERLEY BC, PECK AW. Effect of valproate on the pharmacokinetics of lamotrigine at steady state. Epilepsia 1992;33 (Suppl. 3):82.
33. BRODIE MJ, YUEN AW. Lamotrigine substitution study: evidence for synergism with sodium valproate? 105 Study Group. Epilepsy Res 1997;26:423-32.
34. KWAN P, BRODIE MJ. Early identification of refractory epilepsy. N Engl J Med 2000;342:314-9.
35. CZAPINSKI PTA. Intravenous valproic acid administration in status epilepticus. Neurik Neurochir Pol 1998;32:11-22 [in Polish].
36. REUNANEN M, DAM M, YUEN AW. A randomised open multicentre comparative trial of lamotrigine and carbamazepine as monotherapy in patients with newly diagnosed or recurrent epilepsy. Epilepsy Res 1996;23: 149-55.