A BHK-21 cell culture-adapted tick-borne encephalitis virus mutant is attenuated for neuroinvasiveness

Vaccine

Volumn 21, Issue 25-26, 2003, Pages 4043-4051

  Goto, Akiko ^a   Hayasaka, Daisuke ^b   Yoshii, Kentarou ^a   Mizutani, Tetsuya ^a   Kariwa, Hiroaki ^a   Takashima, Ikuo ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Attenuation; Cell adapted mutant virus; Tick borne encephalitis virus

Indexed keywords

ANTIVIRUS AGENT; CHONDROITIN 4 SULFATE; GLYCOSAMINOGLYCAN; HEPARIN; NEUTRALIZING ANTIBODY; PROTEIN E; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIVIRAL ACTIVITY; ARTICLE; BRAIN; CELL STRAIN BHK; CONTROLLED STUDY; GENETIC ANALYSIS; INOCULATION; MALE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; SPLEEN; TICK BORNE ENCEPHALITIS; TICK BORNE ENCEPHALITIS FLAVIVIRUS; VIREMIA; VIRUS ATTENUATION; VIRUS CLASSIFICATION; VIRUS DETECTION; VIRUS INHIBITION; VIRUS MUTANT; VIRUS TITRATION; VIRUS VIRULENCE;

EID: 0242317458     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(03)00269-X     Document Type: Article

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