Elevated mutagenesis and decreased DNA repair at a transgene are associated with proliferation but not apoptosis in p53-deficient cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 22, 2003, Pages 12853-12858

  Bielas, Jason H ^a   Heddle, John A ^a  

^a YORK UNIVERSITY   (Canada)

Author keywords

Carcinogenesis; Cell cycle; Lacl

Indexed keywords

BETA GALACTOSIDASE; PROTEIN P53;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CARCINOGENIC ACTIVITY; CELL CYCLE; CELL PROLIFERATION; CELL PROTECTION; DNA REPAIR; EMBRYO; FIBROBLAST; GENE FUNCTION; GENE MUTATION; GENE TARGETING; GENOME; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; TRANSGENE;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL CYCLE; CELL DIVISION; CROSSES, GENETIC; DNA PRIMERS; DNA REPAIR; ETHYLNITROSOUREA; FEMALE; FLOW CYTOMETRY; GENES, P53; GENOTYPE; HOMOZYGOTE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS; MUTAGENS; PREGNANCY; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MURINAE;

EID: 0242300089     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2235595100     Document Type: Article

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